4XEM
Crystal Structure of wild type human AlaRS catalytic domain
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 23 |
| Details | binding site for residue A5A A 501 |
| Chain | Residue |
| A | ALA44 |
| A | GLU213 |
| A | ILE214 |
| A | ASN216 |
| A | VAL218 |
| A | ASP239 |
| A | THR240 |
| A | GLY241 |
| A | GLY243 |
| A | ARG246 |
| A | EDO503 |
| A | ARG77 |
| A | HOH702 |
| A | HOH711 |
| A | HOH790 |
| A | HOH953 |
| A | TYR93 |
| A | HIS94 |
| A | HIS95 |
| A | PHE98 |
| A | MET100 |
| A | TRP176 |
| A | GLU189 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 502 |
| Chain | Residue |
| A | HIS336 |
| A | ALA341 |
| A | SER342 |
| A | ARG343 |
| A | LEU383 |
| A | HOH759 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 503 |
| Chain | Residue |
| A | GLU189 |
| A | A5A501 |
| A | HOH837 |
| A | HOH953 |
| A | HOH1087 |
| A | HOH1088 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 504 |
| Chain | Residue |
| A | MET171 |
| A | ARG224 |
| A | ASN317 |
| A | TYR322 |
| A | HOH602 |
| A | HOH629 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 505 |
| Chain | Residue |
| A | PHE267 |
| A | PRO278 |
| A | TYR279 |
| A | TYR295 |
| A | HOH620 |
| A | HOH681 |
| A | HOH908 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 506 |
| Chain | Residue |
| A | GLN12 |
| A | TYR25 |
| A | ARG277 |
| A | HOH607 |
| A | HOH623 |
| A | HOH666 |
| A | HOH684 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"27622773","evidenceCode":"ECO:0000269"},{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"DEC-2014","submissionDatabase":"PDB data bank","title":"Crystal structure of wild type human AlaRS catalytic domain.","authors":["Zhou H.","Yang X.L."]}},{"source":"PDB","id":"4XEM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4XEO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5KNN","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
