4XDD
Apo [FeFe]-Hydrogenase CpI
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005506 | molecular_function | iron ion binding |
| A | 0008901 | molecular_function | ferredoxin hydrogenase activity |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0051536 | molecular_function | iron-sulfur cluster binding |
| A | 0051539 | molecular_function | 4 iron, 4 sulfur cluster binding |
| B | 0005506 | molecular_function | iron ion binding |
| B | 0008901 | molecular_function | ferredoxin hydrogenase activity |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0051536 | molecular_function | iron-sulfur cluster binding |
| B | 0051539 | molecular_function | 4 iron, 4 sulfur cluster binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | binding site for residue SF4 A 601 |
| Chain | Residue |
| A | CYS300 |
| A | PRO301 |
| A | CYS355 |
| A | ALA498 |
| A | CYS499 |
| A | CYS503 |
| A | GLY506 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | binding site for residue SF4 A 602 |
| Chain | Residue |
| A | MET166 |
| A | CYS190 |
| A | LEU191 |
| A | LEU192 |
| A | CYS193 |
| A | GLY194 |
| A | CYS196 |
| A | CYS157 |
| A | THR163 |
| site_id | AC3 |
| Number of Residues | 10 |
| Details | binding site for residue SF4 A 603 |
| Chain | Residue |
| A | CYS147 |
| A | LEU148 |
| A | LEU149 |
| A | CYS150 |
| A | GLY151 |
| A | CYS153 |
| A | CYS200 |
| A | VAL202 |
| A | ALA204 |
| A | LEU205 |
| site_id | AC4 |
| Number of Residues | 9 |
| Details | binding site for residue SF4 A 604 |
| Chain | Residue |
| A | HIS94 |
| A | GLU95 |
| A | LYS97 |
| A | CYS98 |
| A | CYS101 |
| A | CYS107 |
| A | LYS146 |
| A | VAL202 |
| A | ALA203 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 605 |
| Chain | Residue |
| A | LEU218 |
| A | HOH887 |
| A | HOH905 |
| A | HOH749 |
| A | HOH1071 |
| A | HOH758 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | binding site for residue FES A 606 |
| Chain | Residue |
| A | LEU33 |
| A | CYS34 |
| A | PHE35 |
| A | CYS46 |
| A | GLU47 |
| A | CYS49 |
| A | CYS62 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 607 |
| Chain | Residue |
| A | ASN40 |
| A | ASP42 |
| A | HOH871 |
| A | HOH1085 |
| A | HOH1095 |
| A | HOH1111 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue CL A 608 |
| Chain | Residue |
| A | ALA230 |
| A | PRO231 |
| A | SER232 |
| A | CYS503 |
| site_id | AC9 |
| Number of Residues | 9 |
| Details | binding site for residue GOL A 609 |
| Chain | Residue |
| A | LYS223 |
| A | LYS333 |
| A | LYS345 |
| A | VAL347 |
| A | LEU372 |
| A | ARG373 |
| A | ASP376 |
| A | HOH704 |
| A | HOH873 |
| site_id | AD1 |
| Number of Residues | 5 |
| Details | binding site for residue CL A 610 |
| Chain | Residue |
| A | ASP404 |
| A | PRO405 |
| A | ALA406 |
| A | HOH1281 |
| A | HOH1333 |
| site_id | AD2 |
| Number of Residues | 7 |
| Details | binding site for residue SF4 B 601 |
| Chain | Residue |
| B | CYS300 |
| B | PRO301 |
| B | CYS355 |
| B | ALA498 |
| B | CYS499 |
| B | CYS503 |
| B | GLY506 |
| site_id | AD3 |
| Number of Residues | 9 |
| Details | binding site for residue SF4 B 602 |
| Chain | Residue |
| B | CYS157 |
| B | THR163 |
| B | MET166 |
| B | CYS190 |
| B | LEU191 |
| B | LEU192 |
| B | CYS193 |
| B | GLY194 |
| B | CYS196 |
| site_id | AD4 |
| Number of Residues | 9 |
| Details | binding site for residue SF4 B 603 |
| Chain | Residue |
| B | CYS147 |
| B | LEU148 |
| B | LEU149 |
| B | CYS150 |
| B | GLY151 |
| B | CYS153 |
| B | CYS200 |
| B | VAL202 |
| B | LEU205 |
| site_id | AD5 |
| Number of Residues | 9 |
| Details | binding site for residue SF4 B 604 |
| Chain | Residue |
| B | LYS97 |
| B | CYS98 |
| B | CYS101 |
| B | CYS107 |
| B | LYS146 |
| B | VAL202 |
| B | ALA203 |
| B | HIS94 |
| B | GLU95 |
| site_id | AD6 |
| Number of Residues | 9 |
| Details | binding site for residue FES B 605 |
| Chain | Residue |
| B | LEU33 |
| B | CYS34 |
| B | PHE35 |
| B | ASN40 |
| B | LYS45 |
| B | CYS46 |
| B | GLU47 |
| B | CYS49 |
| B | CYS62 |
| site_id | AD7 |
| Number of Residues | 4 |
| Details | binding site for residue CL B 606 |
| Chain | Residue |
| B | ALA230 |
| B | PRO231 |
| B | SER232 |
| B | CYS503 |
| site_id | AD8 |
| Number of Residues | 5 |
| Details | binding site for residue CL B 607 |
| Chain | Residue |
| B | ASP404 |
| B | PRO405 |
| B | ALA406 |
| B | HOH1278 |
| B | HOH1312 |
| site_id | AD9 |
| Number of Residues | 6 |
| Details | binding site for residue MG B 608 |
| Chain | Residue |
| B | LEU218 |
| B | HOH711 |
| B | HOH879 |
| B | HOH954 |
| B | HOH994 |
| B | HOH735 |
| site_id | AE1 |
| Number of Residues | 6 |
| Details | binding site for residue MG B 609 |
| Chain | Residue |
| B | ASN40 |
| B | ASP42 |
| B | HOH899 |
| B | HOH1052 |
| B | HOH1081 |
| B | HOH1097 |
| site_id | AE2 |
| Number of Residues | 10 |
| Details | binding site for residue GOL B 610 |
| Chain | Residue |
| B | LYS223 |
| B | LYS333 |
| B | LYS345 |
| B | VAL347 |
| B | PHE348 |
| B | LEU372 |
| B | ARG373 |
| B | ASP376 |
| B | HOH855 |
| B | HOH869 |
| site_id | AE3 |
| Number of Residues | 3 |
| Details | binding site for residue GOL B 611 |
| Chain | Residue |
| B | GLN366 |
| B | PHE570 |
| B | LYS571 |
Functional Information from PROSITE/UniProt
| site_id | PS00198 |
| Number of Residues | 12 |
| Details | 4FE4S_FER_1 4Fe-4S ferredoxin-type iron-sulfur binding region signature. ClLCGrCVnACG |
| Chain | Residue | Details |
| A | CYS147-GLY158 | |
| A | CYS190-PRO201 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 154 |
| Details | Domain: {"description":"2Fe-2S ferredoxin-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU00465","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 78 |
| Details | Domain: {"description":"4Fe-4S His(Cys)3-ligated-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU01184","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 58 |
| Details | Domain: {"description":"4Fe-4S ferredoxin-type 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00711","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 58 |
| Details | Domain: {"description":"4Fe-4S ferredoxin-type 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00711","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 30 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"10529166","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9836629","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU01184","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"10529166","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU01184","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"10529166","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9836629","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"10529166","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
