4XC5
CRYSTAL STRUCTURE OF THE T1L REOVIRUS ATTACHMENT PROTEIN SIGMA1
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003700 | molecular_function | DNA-binding transcription factor activity |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
| A | 0007155 | biological_process | cell adhesion |
| A | 0019058 | biological_process | viral life cycle |
| A | 0019062 | biological_process | virion attachment to host cell |
| B | 0003700 | molecular_function | DNA-binding transcription factor activity |
| B | 0006355 | biological_process | regulation of DNA-templated transcription |
| B | 0007155 | biological_process | cell adhesion |
| B | 0019058 | biological_process | viral life cycle |
| B | 0019062 | biological_process | virion attachment to host cell |
| C | 0003700 | molecular_function | DNA-binding transcription factor activity |
| C | 0006355 | biological_process | regulation of DNA-templated transcription |
| C | 0007155 | biological_process | cell adhesion |
| C | 0019058 | biological_process | viral life cycle |
| C | 0019062 | biological_process | virion attachment to host cell |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 2 |
| Details | binding site for residue CL A 501 |
| Chain | Residue |
| A | GLY398 |
| B | ASN321 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 502 |
| Chain | Residue |
| A | ASN375 |
| A | ASN375 |
| A | SER376 |
| A | SER376 |
| A | THR454 |
| A | THR454 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue ACT A 503 |
| Chain | Residue |
| B | VAL326 |
| B | ALA327 |
| B | GLY331 |
| A | ASP363 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 504 |
| Chain | Residue |
| A | VAL354 |
| A | THR355 |
| A | SER370 |
| A | GLN371 |
| A | MET372 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | binding site for residue GOL A 505 |
| Chain | Residue |
| A | ASP426 |
| C | THR449 |
| C | TYR450 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | binding site for residue CL B 501 |
| Chain | Residue |
| B | GLY398 |
| C | ASN321 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | binding site for residue MG B 502 |
| Chain | Residue |
| B | ASN375 |
| B | ASN375 |
| B | SER376 |
| B | SER376 |
| B | THR454 |
| B | THR454 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue ACT B 503 |
| Chain | Residue |
| B | ASP363 |
| C | VAL326 |
| C | ALA327 |
| C | GLY331 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | binding site for residue GOL B 504 |
| Chain | Residue |
| B | VAL354 |
| B | THR355 |
| B | SER370 |
| B | GLN371 |
| B | MET372 |
| B | HOH606 |
| site_id | AD1 |
| Number of Residues | 5 |
| Details | binding site for residue GOL B 505 |
| Chain | Residue |
| B | THR449 |
| B | TYR450 |
| C | ARG424 |
| C | ILE425 |
| C | ASP426 |
| site_id | AD2 |
| Number of Residues | 3 |
| Details | binding site for residue GOL B 506 |
| Chain | Residue |
| A | THR449 |
| A | TYR450 |
| B | ASP426 |
| site_id | AD3 |
| Number of Residues | 2 |
| Details | binding site for residue CL C 501 |
| Chain | Residue |
| A | ASN321 |
| C | GLY398 |
| site_id | AD4 |
| Number of Residues | 6 |
| Details | binding site for residue MG C 502 |
| Chain | Residue |
| C | ASN375 |
| C | ASN375 |
| C | SER376 |
| C | SER376 |
| C | THR454 |
| C | THR454 |
| site_id | AD5 |
| Number of Residues | 3 |
| Details | binding site for residue ACT C 503 |
| Chain | Residue |
| A | ALA327 |
| A | GLY331 |
| C | ASP363 |
| site_id | AD6 |
| Number of Residues | 6 |
| Details | binding site for residue GOL C 504 |
| Chain | Residue |
| A | ALA320 |
| A | ASN321 |
| C | VAL388 |
| C | GLN396 |
| C | THR397 |
| C | HOH604 |
| site_id | AD7 |
| Number of Residues | 5 |
| Details | binding site for residue GOL C 505 |
| Chain | Residue |
| C | VAL354 |
| C | THR355 |
| C | SER370 |
| C | GLN371 |
| C | MET372 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 51 |
| Details | Region: {"description":"Binding to GM2 ganglioside","evidences":[{"source":"PubMed","id":"23236285","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine; by host","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
