4X9S

CRYSTAL STRUCTURE OF HISAP FROM STREPTOMYCES SP. MG1

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000105	biological_process	L-histidine biosynthetic process
A	0000162	biological_process	L-tryptophan biosynthetic process
A	0003949	molecular_function	1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity
A	0004640	molecular_function	phosphoribosylanthranilate isomerase activity
A	0005737	cellular_component	cytoplasm

Functional Information from PDB Data

site_id	AC1
Number of Residues	9
Details	binding site for residue SO4 A 301

Chain	Residue
A	ALA59
A	GLY85
A	ARG87
A	GLY106
A	THR107
A	ARG141
A	HOH465
A	HOH476
A	HOH616

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site_id	AC2
Number of Residues	5
Details	binding site for residue SO4 A 302

Chain	Residue
A	THR112
A	PRO113
A	GLU114
A	TRP115
A	HOH575

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site_id	AC3
Number of Residues	11
Details	binding site for residue SO4 A 303

Chain	Residue
A	ARG21
A	ASP173
A	GLY174
A	GLY200
A	GLY224
A	LYS225
A	HOH473
A	HOH475
A	HOH481
A	HOH489
A	HOH491

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site_id	AC4
Number of Residues	3
Details	binding site for residue SO4 A 304

Chain	Residue
A	ARG208
A	LYS239
A	VAL240

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site_id	AC5
Number of Residues	8
Details	binding site for residue SO4 A 305

Chain	Residue
A	ALA11
A	ASP13
A	ARG21
A	HIS52
A	VAL54
A	HOH503
A	HOH515
A	HOH598

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