4X9S
CRYSTAL STRUCTURE OF HISAP FROM STREPTOMYCES SP. MG1
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000105 | biological_process | L-histidine biosynthetic process |
| A | 0000162 | biological_process | L-tryptophan biosynthetic process |
| A | 0003949 | molecular_function | 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity |
| A | 0004640 | molecular_function | phosphoribosylanthranilate isomerase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0008652 | biological_process | amino acid biosynthetic process |
| A | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| A | 0016853 | molecular_function | isomerase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | binding site for residue SO4 A 301 |
| Chain | Residue |
| A | ALA59 |
| A | GLY85 |
| A | ARG87 |
| A | GLY106 |
| A | THR107 |
| A | ARG141 |
| A | HOH465 |
| A | HOH476 |
| A | HOH616 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 A 302 |
| Chain | Residue |
| A | THR112 |
| A | PRO113 |
| A | GLU114 |
| A | TRP115 |
| A | HOH575 |
| site_id | AC3 |
| Number of Residues | 11 |
| Details | binding site for residue SO4 A 303 |
| Chain | Residue |
| A | ARG21 |
| A | ASP173 |
| A | GLY174 |
| A | GLY200 |
| A | GLY224 |
| A | LYS225 |
| A | HOH473 |
| A | HOH475 |
| A | HOH481 |
| A | HOH489 |
| A | HOH491 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 304 |
| Chain | Residue |
| A | ARG208 |
| A | LYS239 |
| A | VAL240 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | binding site for residue SO4 A 305 |
| Chain | Residue |
| A | ALA11 |
| A | ASP13 |
| A | ARG21 |
| A | HIS52 |
| A | VAL54 |
| A | HOH503 |
| A | HOH515 |
| A | HOH598 |
