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4X8Y

Crystal structure of human PGRMC1 cytochrome b5-like domain

Functional Information from PDB Data
site_idAC1
Number of Residues14
Detailsbinding site for residue HEM A 500
ChainResidue
ALYS105
BGLY67
BSER68
BPRO69
BGLU70
BHOH610
APHE106
ATYR107
ATYR113
AGLY124
ACYS129
ATRP156
ALYS163
ATYR164

site_idAC2
Number of Residues13
Detailsbinding site for residue HEM B 500
ChainResidue
BPHE106
BTYR107
BTYR113
BGLY124
BLEU125
BPHE128
BCYS129
BLEU130
BTRP156
BLYS163
BTYR164
BHOH603
BHOH621

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsBINDING: axial binding residue => ECO:0000269|PubMed:26988023, ECO:0007744|PDB:4X8Y
ChainResidueDetails
ATYR113
BTYR113

site_idSWS_FT_FI2
Number of Residues2
DetailsMOD_RES: Phosphothreonine => ECO:0007744|PubMed:24275569
ChainResidueDetails
ATHR74
BTHR74

site_idSWS_FT_FI3
Number of Residues2
DetailsMOD_RES: Phosphoserine => ECO:0000269|Ref.7, ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569
ChainResidueDetails
ASER181
BSER181

226707

PDB entries from 2024-10-30

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