Functional Information from GO Data
| Chain | GOid | namespace | contents |
| H | 0004252 | molecular_function | serine-type endopeptidase activity |
| H | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | binding site for residue 3Z7 H 301 |
| Chain | Residue |
| H | ASP189 |
| H | TYR228 |
| H | SER190 |
| H | LYS192 |
| H | SER195 |
| H | SER214 |
| H | TRP215 |
| H | GLY219 |
| H | CYS220 |
| H | VAL227 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue CA H 302 |
| Chain | Residue |
| H | GLU70 |
| H | ASP72 |
| H | GLU75 |
| H | GLU80 |
| H | HOH401 |
| H | HOH447 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 H 303 |
| Chain | Residue |
| H | ARG83 |
| H | ARG84 |
| H | HIS109 |
| H | GLN110 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 H 304 |
| Chain | Residue |
| H | VAL35 |
| H | ASN37 |
| H | LYS60 |
| H | ILE60 |
| H | LYS60 |
| H | ASN60 |
| H | GOL309 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 H 305 |
| Chain | Residue |
| H | SER170 |
| H | ILE176 |
| H | HIS224 |
| H | PHE225 |
| H | VAL227 |
| H | HOH616 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 H 306 |
| Chain | Residue |
| H | ILE47 |
| H | ASN48 |
| H | GLN239 |
| H | HOH450 |
| H | HOH522 |
| H | HOH576 |
| L | HIS115 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | binding site for residue GOL H 307 |
| Chain | Residue |
| H | PHE59 |
| H | ASP60 |
| H | TRP61 |
| H | PRO96 |
| H | LEU251 |
| H | HOH472 |
| H | HOH546 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | binding site for residue GOL H 308 |
| Chain | Residue |
| H | CYS22 |
| H | GLU26 |
| H | CYS27 |
| H | LEU137 |
| L | ILE138 |
| site_id | AC9 |
| Number of Residues | 2 |
| Details | binding site for residue GOL H 309 |
| Chain | Residue |
| H | LEU41 |
| H | SO4304 |
Functional Information from PROSITE/UniProt
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. VSAAHC |
| Chain | Residue | Details |
| H | VAL53-CYS58 | |
| site_id | PS00135 |
| Number of Residues | 12 |
| Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. DSckGDSGGPHA |
| Chain | Residue | Details |
| H | ASP189-ALA200 | |
| site_id | PS01186 |
| Number of Residues | 16 |
| Details | EGF_2 EGF-like domain signature 2. CrCheGYslladgvsC |
| Chain | Residue | Details |
| L | CYS112-CYS127 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | ACT_SITE: Charge relay system => ECO:0000250 |
| Chain | Residue | Details |
| H | HIS57 | |
| H | ASP102 | |
| H | SER195 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000250 |
| Chain | Residue | Details |
| H | ASP189 | |
| Chain | Residue | Details |
| H | ASN175 | |
