4X8I

de novo crystal structure of the Pyrococcus Furiosus TET3 aminopeptidase

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004177	molecular_function	aminopeptidase activity
A	0006508	biological_process	proteolysis
A	0008237	molecular_function	metallopeptidase activity
A	0046872	molecular_function	metal ion binding
B	0004177	molecular_function	aminopeptidase activity
B	0006508	biological_process	proteolysis
B	0008237	molecular_function	metallopeptidase activity
B	0046872	molecular_function	metal ion binding
C	0004177	molecular_function	aminopeptidase activity
C	0006508	biological_process	proteolysis
C	0008237	molecular_function	metallopeptidase activity
C	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	binding site for residue ZN A 401

Chain	Residue
A	HIS63
A	ASP177
A	GLU207
A	ASP230
A	CO402
A	CL403
A	HOH577

---

site_id	AC2
Number of Residues	5
Details	binding site for residue CO A 402

Chain	Residue
A	HIS314
A	ZN401
A	CL403
A	ASP177
A	GLU208

---

site_id	AC3
Number of Residues	6
Details	binding site for residue CL A 403

Chain	Residue
A	GLU207
A	ASP230
A	GLY288
A	ZN401
A	CO402
A	HOH577

---

site_id	AC4
Number of Residues	1
Details	binding site for residue GD A 404

Chain	Residue
A	GLU299

---

site_id	AC5
Number of Residues	1
Details	binding site for residue GD A 405

Chain	Residue
A	GLU168

---

site_id	AC6
Number of Residues	1
Details	binding site for residue GD A 406

Chain	Residue
A	ASP132

---

site_id	AC7
Number of Residues	6
Details	binding site for residue ZN B 401

Chain	Residue
B	HIS63
B	ASP177
B	GLU207
B	ASP230
B	CO402
B	CL403

---

site_id	AC8
Number of Residues	6
Details	binding site for residue CO B 402

Chain	Residue
B	ASP177
B	GLU208
B	HIS314
B	ZN401
B	HOH555
B	HOH558

---

site_id	AC9
Number of Residues	5
Details	binding site for residue CL B 403

Chain	Residue
B	GLU207
B	ASP230
B	GLY288
B	ZN401
B	HOH558

---

site_id	AD1
Number of Residues	1
Details	binding site for residue GD B 404

Chain	Residue
B	GLU275

---

site_id	AD2
Number of Residues	1
Details	binding site for residue GD B 405

Chain	Residue
B	GLU194

---

site_id	AD3
Number of Residues	2
Details	binding site for residue GD B 406

Chain	Residue
B	HOH560
B	HOH561

---

site_id	AD4
Number of Residues	1
Details	binding site for residue GD B 407

Chain	Residue
B	ASP132

---

site_id	AD5
Number of Residues	6
Details	binding site for residue ZN C 401

Chain	Residue
C	HIS63
C	ASP177
C	GLU207
C	ASP230
C	CO402
C	CL403

---

site_id	AD6
Number of Residues	7
Details	binding site for residue CO C 402

Chain	Residue
C	ASP177
C	GLU208
C	HIS314
C	ZN401
C	CL403
C	HOH554
C	HOH556

---

site_id	AD7
Number of Residues	6
Details	binding site for residue CL C 403

Chain	Residue
C	GLU207
C	ASP230
C	GLY288
C	ZN401
C	CO402
C	HOH554

---

site_id	AD8
Number of Residues	2
Details	binding site for residue GD C 404

Chain	Residue
C	GLU275
C	DO3408

---

site_id	AD9
Number of Residues	1
Details	binding site for residue GD C 405

Chain	Residue
C	GLU148

---

site_id	AE1
Number of Residues	1
Details	binding site for residue GD C 406

Chain	Residue
C	GLU299

---

site_id	AE2
Number of Residues	1
Details	binding site for residue GD C 407

Chain	Residue
C	ASP132

---

site_id	AE3
Number of Residues	7
Details	binding site for residue DO3 C 408

Chain	Residue
B	LYS33
B	ASP34
B	ALA36
B	ASP37
C	GLU194
C	GLU275
C	GD404

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	ACT_SITE: Proton acceptor => ECO:0000250

Chain	Residue	Details
A	GLU207
B	GLU207
C	GLU207

---

site_id	SWS_FT_FI2
Number of Residues	15
Details	BINDING: BINDING => ECO:0000250

Chain	Residue	Details
A	HIS63
B	HIS314
C	HIS63
C	ASP177
C	GLU208
C	ASP230
C	HIS314
A	ASP177
A	GLU208
A	ASP230
A	HIS314
B	HIS63
B	ASP177
B	GLU208
B	ASP230

---