4X4S
Crystal structure of the A.fulgidus CCA-adding enzyme in complex with a G70A arginyl-tRNA minihelix ending in CCACC and CTP
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000049 | molecular_function | tRNA binding |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0001680 | biological_process | tRNA 3'-terminal CCA addition |
| A | 0003723 | molecular_function | RNA binding |
| A | 0004810 | molecular_function | CCA tRNA nucleotidyltransferase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0008033 | biological_process | tRNA processing |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016779 | molecular_function | nucleotidyltransferase activity |
| A | 0031123 | biological_process | RNA 3'-end processing |
| A | 0042245 | biological_process | RNA repair |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0106354 | biological_process | tRNA surveillance |
| A | 0160016 | molecular_function | CCACCA tRNA nucleotidyltransferase activity |
| C | 0000049 | molecular_function | tRNA binding |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0000287 | molecular_function | magnesium ion binding |
| C | 0001680 | biological_process | tRNA 3'-terminal CCA addition |
| C | 0003723 | molecular_function | RNA binding |
| C | 0004810 | molecular_function | CCA tRNA nucleotidyltransferase activity |
| C | 0005524 | molecular_function | ATP binding |
| C | 0008033 | biological_process | tRNA processing |
| C | 0016740 | molecular_function | transferase activity |
| C | 0016779 | molecular_function | nucleotidyltransferase activity |
| C | 0031123 | biological_process | RNA 3'-end processing |
| C | 0042245 | biological_process | RNA repair |
| C | 0046872 | molecular_function | metal ion binding |
| C | 0106354 | biological_process | tRNA surveillance |
| C | 0160016 | molecular_function | CCACCA tRNA nucleotidyltransferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 11 |
| Details | binding site for residue CTP A 501 |
| Chain | Residue |
| A | SER47 |
| B | C36 |
| B | C37 |
| A | ARG50 |
| A | THR130 |
| A | HIS133 |
| A | TYR161 |
| A | ALA163 |
| A | ARG224 |
| A | MG502 |
| B | A35 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue MG A 502 |
| Chain | Residue |
| A | SER47 |
| A | GLU59 |
| A | ASP61 |
| A | CTP501 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | binding site for residue GOL A 503 |
| Chain | Residue |
| A | ARG209 |
| A | GLU222 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue TAR A 504 |
| Chain | Residue |
| A | HIS240 |
| A | ARG243 |
| C | GLU352 |
| C | VAL355 |
| C | LYS356 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue PEG A 505 |
| Chain | Residue |
| A | PHE349 |
| A | GLU352 |
| A | VAL355 |
| C | HIS240 |
| C | ARG243 |
| C | GLU247 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | binding site for residue GOL A 506 |
| Chain | Residue |
| A | ARG317 |
| A | SER318 |
| C | GLU370 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 507 |
| Chain | Residue |
| A | ARG284 |
| A | LYS285 |
| A | ASN403 |
| A | SER407 |
| A | GLU410 |
| site_id | AC8 |
| Number of Residues | 12 |
| Details | binding site for residue CTP C 501 |
| Chain | Residue |
| C | SER47 |
| C | ARG50 |
| C | HIS133 |
| C | TYR161 |
| C | ALA163 |
| C | SER171 |
| C | TYR173 |
| C | ARG224 |
| C | MG502 |
| D | A35 |
| D | C36 |
| D | C37 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | binding site for residue MG C 502 |
| Chain | Residue |
| C | SER47 |
| C | GLU59 |
| C | ASP61 |
| C | CTP501 |
| site_id | AD1 |
| Number of Residues | 2 |
| Details | binding site for residue GOL C 503 |
| Chain | Residue |
| C | GLU311 |
| C | ARG344 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"14592988","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"14636575","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25640237","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1R89","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1UEU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4X4O","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4X4Q","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4X4S","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"14592988","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"14636575","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25640237","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1R89","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1UEU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4X4Q","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4X4S","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"14592988","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1UEV","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"14592988","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1R89","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1UEV","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
