4X4P

Crystal structure of the A.fulgidus CCA-adding enzyme in complex with a G70A arginyl-tRNA minihelix ending in CCAC

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000049	molecular_function	tRNA binding
A	0000287	molecular_function	magnesium ion binding
A	0001680	biological_process	tRNA 3'-terminal CCA addition
A	0003723	molecular_function	RNA binding
A	0004810	molecular_function	CCA tRNA nucleotidyltransferase activity
A	0005524	molecular_function	ATP binding
A	0008033	biological_process	tRNA processing
A	0016779	molecular_function	nucleotidyltransferase activity
A	0031123	biological_process	RNA 3'-end processing
A	0042245	biological_process	RNA repair
A	0046872	molecular_function	metal ion binding
A	0106354	biological_process	tRNA surveillance
A	0160016	molecular_function	CCACCA tRNA nucleotidyltransferase activity
C	0000049	molecular_function	tRNA binding
C	0000287	molecular_function	magnesium ion binding
C	0001680	biological_process	tRNA 3'-terminal CCA addition
C	0003723	molecular_function	RNA binding
C	0004810	molecular_function	CCA tRNA nucleotidyltransferase activity
C	0005524	molecular_function	ATP binding
C	0008033	biological_process	tRNA processing
C	0016779	molecular_function	nucleotidyltransferase activity
C	0031123	biological_process	RNA 3'-end processing
C	0042245	biological_process	RNA repair
C	0046872	molecular_function	metal ion binding
C	0106354	biological_process	tRNA surveillance
C	0160016	molecular_function	CCACCA tRNA nucleotidyltransferase activity
E	0000049	molecular_function	tRNA binding
E	0000287	molecular_function	magnesium ion binding
E	0001680	biological_process	tRNA 3'-terminal CCA addition
E	0003723	molecular_function	RNA binding
E	0004810	molecular_function	CCA tRNA nucleotidyltransferase activity
E	0005524	molecular_function	ATP binding
E	0008033	biological_process	tRNA processing
E	0016779	molecular_function	nucleotidyltransferase activity
E	0031123	biological_process	RNA 3'-end processing
E	0042245	biological_process	RNA repair
E	0046872	molecular_function	metal ion binding
E	0106354	biological_process	tRNA surveillance
E	0160016	molecular_function	CCACCA tRNA nucleotidyltransferase activity
G	0000049	molecular_function	tRNA binding
G	0000287	molecular_function	magnesium ion binding
G	0001680	biological_process	tRNA 3'-terminal CCA addition
G	0003723	molecular_function	RNA binding
G	0004810	molecular_function	CCA tRNA nucleotidyltransferase activity
G	0005524	molecular_function	ATP binding
G	0008033	biological_process	tRNA processing
G	0016779	molecular_function	nucleotidyltransferase activity
G	0031123	biological_process	RNA 3'-end processing
G	0042245	biological_process	RNA repair
G	0046872	molecular_function	metal ion binding
G	0106354	biological_process	tRNA surveillance
G	0160016	molecular_function	CCACCA tRNA nucleotidyltransferase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue SO4 A 501

Chain	Residue
A	SER47
A	LEU54
A	SER57
A	TYR161
B	C36

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site_id	AC2
Number of Residues	2
Details	binding site for residue SO4 A 502

Chain	Residue
A	SER231
A	LEU232

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site_id	AC3
Number of Residues	2
Details	binding site for residue SO4 A 503

Chain	Residue
A	ARG299
A	LYS303

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site_id	AC4
Number of Residues	3
Details	binding site for residue SO4 A 504

Chain	Residue
A	GLN348
A	ARG373
C	ARG197

---

site_id	AC5
Number of Residues	5
Details	binding site for residue SO4 A 505

Chain	Residue
A	ARG50
A	THR130
A	HIS133
A	TYR173
B	C36

---

site_id	AC6
Number of Residues	6
Details	binding site for residue SO4 C 501

Chain	Residue
C	SER47
C	TRP53
C	LEU54
C	SER57
C	LYS152
C	TYR161

---

site_id	AC7
Number of Residues	6
Details	binding site for residue SO4 E 501

Chain	Residue
E	SER47
E	TRP53
E	LEU54
E	SER57
E	LYS152
E	TYR161

---

site_id	AC8
Number of Residues	2
Details	binding site for residue SO4 E 502

Chain	Residue
E	GLN348
E	ARG373

---

site_id	AC9
Number of Residues	6
Details	binding site for residue SO4 G 501

Chain	Residue
G	SER47
G	TRP53
G	LEU54
G	SER57
G	LYS152
G	TYR161

---

site_id	AD1
Number of Residues	3
Details	binding site for residue SO4 G 502

Chain	Residue
E	ARG197
G	GLN348
G	ARG373

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	BINDING: BINDING => ECO:0000269|PubMed:14592988, ECO:0000269|PubMed:14636575, ECO:0000269|PubMed:25640237, ECO:0007744|PDB:1R89, ECO:0007744|PDB:1UEU, ECO:0007744|PDB:4X4O, ECO:0007744|PDB:4X4Q, ECO:0007744|PDB:4X4S

Chain	Residue	Details
A	SER47
C	SER47
E	SER47
G	SER47

---

site_id	SWS_FT_FI2
Number of Residues	16
Details	BINDING: BINDING => ECO:0000269|PubMed:14592988, ECO:0000269|PubMed:14636575, ECO:0000269|PubMed:25640237, ECO:0007744|PDB:1R89, ECO:0007744|PDB:1UEU, ECO:0007744|PDB:4X4Q, ECO:0007744|PDB:4X4S

Chain	Residue	Details
A	ARG50
E	HIS133
E	LYS152
E	TYR161
G	ARG50
G	HIS133
G	LYS152
G	TYR161
A	HIS133
A	LYS152
A	TYR161
C	ARG50
C	HIS133
C	LYS152
C	TYR161
E	ARG50

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	BINDING: BINDING => ECO:0000269|PubMed:14592988, ECO:0007744|PDB:1UEV

Chain	Residue	Details
A	GLU59
C	GLU59
E	GLU59
G	GLU59

---

site_id	SWS_FT_FI4
Number of Residues	8
Details	BINDING: BINDING => ECO:0000269|PubMed:14592988, ECO:0007744|PDB:1R89, ECO:0007744|PDB:1UEV

Chain	Residue	Details
A	ASP61
A	ASP110
C	ASP61
C	ASP110
E	ASP61
E	ASP110
G	ASP61
G	ASP110

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