4X36

Crystal structure of the autolysin LytA from Streptococcus pneumoniae TIGR4

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005576	cellular_component	extracellular region
A	0008745	molecular_function	N-acetylmuramoyl-L-alanine amidase activity
A	0009253	biological_process	peptidoglycan catabolic process
A	0016787	molecular_function	hydrolase activity
A	0030420	biological_process	establishment of competence for transformation
A	0030435	biological_process	sporulation resulting in formation of a cellular spore
A	0071555	biological_process	cell wall organization

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	binding site for residue GOL A 401

Chain	Residue
A	ASN111
A	GLU115
A	TRP157
A	HOH515
A	HOH517
A	HOH534
A	HOH545

---

site_id	AC2
Number of Residues	3
Details	binding site for residue GOL A 402

Chain	Residue
A	TYR41
A	ASN30
A	GLU38

---

site_id	AC3
Number of Residues	8
Details	binding site for residue GOL A 403

Chain	Residue
A	GLN18
A	ASP68
A	GLY192
A	TYR194
A	HOH501
A	HOH516
A	HOH535
A	HOH541

---

site_id	AC4
Number of Residues	5
Details	binding site for residue GOL A 404

Chain	Residue
A	ARG9
A	THR10
A	ASP11
A	TRP43
A	HOH510

---

site_id	AC5
Number of Residues	3
Details	binding site for residue GOL A 405

Chain	Residue
A	GLY77
A	ASN79
A	GOL406

---

site_id	AC6
Number of Residues	3
Details	binding site for residue GOL A 406

Chain	Residue
A	GLU48
A	GOL405
A	HOH574

---

site_id	AC7
Number of Residues	4
Details	binding site for residue ZN A 407

Chain	Residue
A	HIS26
A	HIS133
A	ASP149
A	HOH563

---

site_id	AC8
Number of Residues	3
Details	binding site for residue CHT A 408

Chain	Residue
A	TRP220
A	TRP228
A	GLU275

---

site_id	AC9
Number of Residues	5
Details	binding site for residue CHT A 409

Chain	Residue
A	TRP248
A	TYR264
A	TYR269
A	HOH540
A	HOH551

---

site_id	AD1
Number of Residues	3
Details	binding site for residue CHT A 410

Chain	Residue
A	TRP261
A	TRP268
A	ASP312

---

site_id	AD2
Number of Residues	5
Details	binding site for residue CHT A 411

Chain	Residue
A	PHE199
A	TRP206
A	GLU254
A	HOH716
A	HOH720

---

site_id	AD3
Number of Residues	4
Details	binding site for residue CHT A 412

Chain	Residue
A	TRP186
A	TYR194
A	SER212
A	TYR214

---