4X2W

Crystal structure of the Murine Norovirus NS6 protease (inactive C139A mutant) with a C-terminal extension to include residues P1 prime - P2 prime of NS7

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004197	molecular_function	cysteine-type endopeptidase activity
A	0006508	biological_process	proteolysis
B	0004197	molecular_function	cysteine-type endopeptidase activity
B	0006508	biological_process	proteolysis

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	ACT_SITE: For 3CLpro activity => ECO:0000255|PROSITE-ProRule:PRU00870

Chain	Residue	Details
A	HIS30
A	ALA139
B	HIS30
B	ALA139

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site_id	SWS_FT_FI2
Number of Residues	2
Details	ACT_SITE: For 3CLpro activity => ECO:0000303|PubMed:26363064

Chain	Residue	Details
A	ASP54
B	ASP54

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