4X1U
The structure of AhpE from Mycobacterium tuberculosis revisited
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004601 | molecular_function | peroxidase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0008379 | molecular_function | thioredoxin peroxidase activity |
| A | 0016209 | molecular_function | antioxidant activity |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0034599 | biological_process | cellular response to oxidative stress |
| A | 0045454 | biological_process | cell redox homeostasis |
| A | 0051409 | biological_process | response to nitrosative stress |
| A | 0051920 | molecular_function | peroxiredoxin activity |
| A | 0098869 | biological_process | cellular oxidant detoxification |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0004601 | molecular_function | peroxidase activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0008379 | molecular_function | thioredoxin peroxidase activity |
| B | 0016209 | molecular_function | antioxidant activity |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0034599 | biological_process | cellular response to oxidative stress |
| B | 0045454 | biological_process | cell redox homeostasis |
| B | 0051409 | biological_process | response to nitrosative stress |
| B | 0051920 | molecular_function | peroxiredoxin activity |
| B | 0098869 | biological_process | cellular oxidant detoxification |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 201 |
| Chain | Residue |
| A | GLN18 |
| A | PRO74 |
| A | HOH380 |
| B | LEU39 |
| B | ALA111 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue GOL A 202 |
| Chain | Residue |
| A | VAL21 |
| A | THR22 |
| A | GLY25 |
| A | TYR26 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | binding site for residue GOL B 201 |
| Chain | Residue |
| B | ASP15 |
| B | GLN16 |
| B | ASN17 |
| B | GLN19 |
| B | THR87 |
| B | PRO89 |
| B | GLN134 |
| B | HOH301 |
| B | HOH311 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | binding site for residue GOL B 202 |
| Chain | Residue |
| B | ASN17 |
| B | GLN19 |
| B | ASN108 |
| B | ASN115 |
| B | HOH304 |
| B | HOH305 |
| B | HOH319 |
| B | HOH341 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue GOL B 203 |
| Chain | Residue |
| A | ALA130 |
| A | HOH336 |
| B | ALA6 |
| B | THR7 |
| B | HOH303 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Cysteine sulfenic acid (-SOH) intermediate","evidences":[{"source":"PubMed","id":"15701515","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19737009","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"1XVW","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
