4X0O

Beta-ketoacyl-(acyl carrier protein) synthase III-2 (FabH2) from Vibrio cholerae soaked with Acetyl-CoA

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004315	molecular_function	3-oxoacyl-[acyl-carrier-protein] synthase activity
A	0005737	cellular_component	cytoplasm
A	0006633	biological_process	fatty acid biosynthetic process
A	0016746	molecular_function	acyltransferase activity
A	0030497	biological_process	fatty acid elongation
A	0033818	molecular_function	beta-ketoacyl-acyl-carrier-protein synthase III activity
B	0004315	molecular_function	3-oxoacyl-[acyl-carrier-protein] synthase activity
B	0005737	cellular_component	cytoplasm
B	0006633	biological_process	fatty acid biosynthetic process
B	0016746	molecular_function	acyltransferase activity
B	0030497	biological_process	fatty acid elongation
B	0033818	molecular_function	beta-ketoacyl-acyl-carrier-protein synthase III activity
C	0004315	molecular_function	3-oxoacyl-[acyl-carrier-protein] synthase activity
C	0005737	cellular_component	cytoplasm
C	0006633	biological_process	fatty acid biosynthetic process
C	0016746	molecular_function	acyltransferase activity
C	0030497	biological_process	fatty acid elongation
C	0033818	molecular_function	beta-ketoacyl-acyl-carrier-protein synthase III activity
D	0004315	molecular_function	3-oxoacyl-[acyl-carrier-protein] synthase activity
D	0005737	cellular_component	cytoplasm
D	0006633	biological_process	fatty acid biosynthetic process
D	0016746	molecular_function	acyltransferase activity
D	0030497	biological_process	fatty acid elongation
D	0033818	molecular_function	beta-ketoacyl-acyl-carrier-protein synthase III activity
E	0004315	molecular_function	3-oxoacyl-[acyl-carrier-protein] synthase activity
E	0005737	cellular_component	cytoplasm
E	0006633	biological_process	fatty acid biosynthetic process
E	0016746	molecular_function	acyltransferase activity
E	0030497	biological_process	fatty acid elongation
E	0033818	molecular_function	beta-ketoacyl-acyl-carrier-protein synthase III activity
F	0004315	molecular_function	3-oxoacyl-[acyl-carrier-protein] synthase activity
F	0005737	cellular_component	cytoplasm
F	0006633	biological_process	fatty acid biosynthetic process
F	0016746	molecular_function	acyltransferase activity
F	0030497	biological_process	fatty acid elongation
F	0033818	molecular_function	beta-ketoacyl-acyl-carrier-protein synthase III activity
G	0004315	molecular_function	3-oxoacyl-[acyl-carrier-protein] synthase activity
G	0005737	cellular_component	cytoplasm
G	0006633	biological_process	fatty acid biosynthetic process
G	0016746	molecular_function	acyltransferase activity
G	0030497	biological_process	fatty acid elongation
G	0033818	molecular_function	beta-ketoacyl-acyl-carrier-protein synthase III activity
H	0004315	molecular_function	3-oxoacyl-[acyl-carrier-protein] synthase activity
H	0005737	cellular_component	cytoplasm
H	0006633	biological_process	fatty acid biosynthetic process
H	0016746	molecular_function	acyltransferase activity
H	0030497	biological_process	fatty acid elongation
H	0033818	molecular_function	beta-ketoacyl-acyl-carrier-protein synthase III activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue COA A 400

Chain	Residue
A	THR31
A	SER32
A	TRP35
A	ARG152

---

site_id	AC2
Number of Residues	5
Details	binding site for residue NA A 401

Chain	Residue
A	GLU244
A	ASP246
A	ASP305
A	HOH506
A	HOH568

---

site_id	AC3
Number of Residues	4
Details	binding site for residue COA B 400

Chain	Residue
B	ASP30
B	THR31
B	TRP35
B	ARG152

---

site_id	AC4
Number of Residues	4
Details	binding site for residue NA B 401

Chain	Residue
B	GLU244
B	ASP246
B	ASP305
B	HOH569

---

site_id	AC5
Number of Residues	6
Details	binding site for residue NA C 401

Chain	Residue
C	GLU244
C	ASP246
C	ASP305
C	HOH526
C	HOH545
C	HOH597

---

site_id	AC6
Number of Residues	3
Details	binding site for residue COA D 400

Chain	Residue
D	THR31
D	TRP35
D	ARG152

---

site_id	AC7
Number of Residues	5
Details	binding site for residue NA D 401

Chain	Residue
D	GLU244
D	ASP246
D	ASP305
D	HOH538
D	HOH564

---

site_id	AC8
Number of Residues	4
Details	binding site for residue COA E 400

Chain	Residue
E	THR31
E	TRP35
E	ARG152
E	VAL156

---

site_id	AC9
Number of Residues	10
Details	binding site for residue COA F 401

Chain	Residue
C	HIS343
C	ASP347
C	HOH573
F	ASP30
F	THR31
F	TRP35
F	ARG39
F	ARG152
F	ASP153
F	HOH567

---

site_id	AD1
Number of Residues	4
Details	binding site for residue NA F 402

Chain	Residue
F	GLU244
F	ASP246
F	ASP305
F	HOH595

---

site_id	AD2
Number of Residues	8
Details	binding site for residue COA G 401

Chain	Residue
B	HIS343
B	ASP347
G	THR31
G	TRP35
G	ARG39
G	ARG152
G	ASP153
G	HOH509

---

site_id	AD3
Number of Residues	5
Details	binding site for residue NA G 402

Chain	Residue
G	GLU244
G	ASP246
G	ASP305
G	HOH560
G	HOH584

---

site_id	AD4
Number of Residues	2
Details	binding site for residue MLI G 403

Chain	Residue
G	ARG94
G	HOH554

---

site_id	AD5
Number of Residues	14
Details	binding site for residue COA H 401

Chain	Residue
H	THR31
H	TRP35
H	ARG39
H	ARG152
H	ASP153
H	PHE214
H	GLY216
H	ILE219
H	PHE220
H	ALA253
H	ASN254
H	ARG256
H	ASN281
H	PHE311

---

site_id	AD6
Number of Residues	3
Details	binding site for residue NA H 402

Chain	Residue
H	GLU244
H	ASP246
H	ASP305

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	32
Details	Region: {"description":"ACP-binding","evidences":[{"source":"HAMAP-Rule","id":"MF_01815","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	24
Details	Active site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01815","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---