4WW7
Crystal structure of binary complex Bud32-Cgi121 in complex with AMP
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0000282 | biological_process | cellular bud site selection |
| A | 0000408 | cellular_component | EKC/KEOPS complex |
| A | 0000722 | biological_process | telomere maintenance via recombination |
| A | 0000723 | biological_process | telomere maintenance |
| A | 0000781 | cellular_component | chromosome, telomeric region |
| A | 0002949 | biological_process | tRNA threonylcarbamoyladenosine modification |
| A | 0004672 | molecular_function | protein kinase activity |
| A | 0004674 | molecular_function | protein serine/threonine kinase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0005654 | cellular_component | nucleoplasm |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006468 | biological_process | protein phosphorylation |
| A | 0008033 | biological_process | tRNA processing |
| A | 0016301 | molecular_function | kinase activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0016887 | molecular_function | ATP hydrolysis activity |
| A | 0045944 | biological_process | positive regulation of transcription by RNA polymerase II |
| A | 0070525 | biological_process | tRNA threonylcarbamoyladenosine metabolic process |
| A | 0106310 | molecular_function | protein serine kinase activity |
| A | 1990145 | biological_process | maintenance of translational fidelity |
| B | 0000049 | molecular_function | tRNA binding |
| B | 0000408 | cellular_component | EKC/KEOPS complex |
| B | 0000722 | biological_process | telomere maintenance via recombination |
| B | 0000723 | biological_process | telomere maintenance |
| B | 0000781 | cellular_component | chromosome, telomeric region |
| B | 0002949 | biological_process | tRNA threonylcarbamoyladenosine modification |
| B | 0005515 | molecular_function | protein binding |
| B | 0005634 | cellular_component | nucleus |
| B | 0005654 | cellular_component | nucleoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0006310 | biological_process | DNA recombination |
| B | 0008033 | biological_process | tRNA processing |
| B | 0045944 | biological_process | positive regulation of transcription by RNA polymerase II |
| B | 1990145 | biological_process | maintenance of translational fidelity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 12 |
| Details | binding site for residue AMP A 301 |
| Chain | Residue |
| A | SER23 |
| A | HOH472 |
| A | HOH475 |
| A | HOH502 |
| A | VAL30 |
| A | ILE50 |
| A | LYS52 |
| A | GLU107 |
| A | LEU109 |
| A | ASP182 |
| A | HOH438 |
| A | HOH458 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue ACT A 302 |
| Chain | Residue |
| A | PHE125 |
| A | HIS129 |
| A | TRP176 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue ACT A 303 |
| Chain | Residue |
| A | LEU191 |
| A | VAL192 |
| A | GLU193 |
| A | ARG246 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue ACT A 304 |
| Chain | Residue |
| A | HIS46 |
| A | GLN47 |
| A | HOH484 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue ACT A 305 |
| Chain | Residue |
| A | LEU199 |
| A | GLU203 |
| A | ASN218 |
| A | MET222 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 306 |
| Chain | Residue |
| A | ARG143 |
| A | LYS216 |
| A | TRP220 |
| A | GLU223 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 A 307 |
| Chain | Residue |
| A | SER135 |
| A | ASP136 |
| A | ARG253 |
| A | ARG257 |
| A | HOH408 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 B 201 |
| Chain | Residue |
| B | LYS68 |
| B | ILE134 |
| B | GLU135 |
| B | ASN140 |
| B | HOH303 |
Functional Information from PROSITE/UniProt
| site_id | PS00109 |
| Number of Residues | 13 |
| Details | PROTEIN_KINASE_TYR Tyrosine protein kinases specific active-site signature. YCHgDLTSSNIVL |
| Chain | Residue | Details |
| A | TYR157-LEU169 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"},{"source":"PROSITE-ProRule","id":"PRU10028","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphoserine; by autocatalysis","evidences":[{"source":"PubMed","id":"12023889","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
