4WUD

N-terminal 43 kDa fragment of the E. coli DNA gyrase B subunit grown from no salt condition

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0003918	molecular_function	DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity
A	0005524	molecular_function	ATP binding
A	0006265	biological_process	DNA topological change

Functional Information from PDB Data

site_id	AC1
Number of Residues	29
Details	binding site for residue ANP A 401

Chain	Residue
A	TYR5
A	GLY101
A	GLY102
A	LYS103
A	TYR109
A	GLY114
A	LEU115
A	HIS116
A	GLY117
A	VAL118
A	GLY119
A	ILE10
A	VAL120
A	GLN335
A	LYS337
A	MG402
A	HOH535
A	HOH536
A	HOH537
A	HOH540
A	HOH544
A	HOH545
A	GLU42
A	ASN46
A	GLU50
A	ASP73
A	ILE78
A	ILE94
A	ALA100

---

site_id	AC2
Number of Residues	4
Details	binding site for residue MG A 402

Chain	Residue
A	ASN46
A	ANP401
A	HOH536
A	HOH537

---

site_id	AC3
Number of Residues	6
Details	binding site for residue NA A 403

Chain	Residue
A	LYS103
A	ASP105
A	HOH527
A	HOH528
A	HOH569
A	HOH609

---

site_id	AC4
Number of Residues	4
Details	binding site for residue CL A 404

Chain	Residue
A	ASP6
A	SER7
A	GLY81
A	ARG136

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Active site: {"description":"Proton acceptor (ATPase activity)","evidences":[{"source":"PubMed","id":"10734094","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"8248233","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"25202966","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25849408","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"10734094","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	9
Details	Binding site: {"evidences":[{"source":"PubMed","id":"10734094","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25202966","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25849408","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	7
Details	Binding site: {"evidences":[{"source":"PubMed","id":"25849408","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"10734094","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25849408","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	1
Details	Site: {"description":"Transition state stabilizer","evidences":[{"source":"PubMed","id":"9657678","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---