4WTW
Crystal structure of the third FnIII domain of integrin beta4
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0007160 | biological_process | cell-matrix adhesion |
| A | 0007229 | biological_process | integrin-mediated signaling pathway |
| A | 0008305 | cellular_component | integrin complex |
| A | 0031581 | biological_process | hemidesmosome assembly |
| A | 0048870 | biological_process | cell motility |
| B | 0007160 | biological_process | cell-matrix adhesion |
| B | 0007229 | biological_process | integrin-mediated signaling pathway |
| B | 0008305 | cellular_component | integrin complex |
| B | 0031581 | biological_process | hemidesmosome assembly |
| B | 0048870 | biological_process | cell motility |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | binding site for residue SO4 A 1601 |
| Chain | Residue |
| A | GLY1500 |
| A | GLU1501 |
| A | HIS1503 |
| A | HOH1715 |
| A | HOH1764 |
| A | HOH1772 |
| A | HOH1778 |
| A | HOH1804 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 A 1602 |
| Chain | Residue |
| A | ARG1475 |
| A | SER1514 |
| A | SER1514 |
| A | HOH1703 |
| A | HOH1703 |
| A | ARG1475 |
| site_id | AC3 |
| Number of Residues | 12 |
| Details | binding site for residue 1PE A 1603 |
| Chain | Residue |
| A | GLN1495 |
| A | LEU1496 |
| A | LEU1497 |
| A | ASN1498 |
| A | GLY1499 |
| A | HOH1727 |
| B | GLN1495 |
| B | LEU1496 |
| B | LEU1497 |
| B | ASN1498 |
| B | GLY1499 |
| B | VAL1527 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 1601 |
| Chain | Residue |
| B | GLN1488 |
| B | TYR1490 |
| B | ASN1506 |
| B | ILE1507 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"16964243","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
