4WSJ
Crystal structure of a bacterial fucodiase in complex with 1-((1R,2R,3R,4R,5R,6R)-2,3,4-trihydroxy-5-methyl-7-azabicyclo[4.1.0]heptan-7-yl)ethan-1-one
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004560 | molecular_function | alpha-L-fucosidase activity |
| A | 0005764 | cellular_component | lysosome |
| A | 0005975 | biological_process | carbohydrate metabolic process |
| A | 0006004 | biological_process | fucose metabolic process |
| A | 0016139 | biological_process | glycoside catabolic process |
| A | 0016787 | molecular_function | hydrolase activity |
| B | 0004560 | molecular_function | alpha-L-fucosidase activity |
| B | 0005764 | cellular_component | lysosome |
| B | 0005975 | biological_process | carbohydrate metabolic process |
| B | 0006004 | biological_process | fucose metabolic process |
| B | 0016139 | biological_process | glycoside catabolic process |
| B | 0016787 | molecular_function | hydrolase activity |
| C | 0004560 | molecular_function | alpha-L-fucosidase activity |
| C | 0005764 | cellular_component | lysosome |
| C | 0005975 | biological_process | carbohydrate metabolic process |
| C | 0006004 | biological_process | fucose metabolic process |
| C | 0016139 | biological_process | glycoside catabolic process |
| C | 0016787 | molecular_function | hydrolase activity |
| D | 0004560 | molecular_function | alpha-L-fucosidase activity |
| D | 0005764 | cellular_component | lysosome |
| D | 0005975 | biological_process | carbohydrate metabolic process |
| D | 0006004 | biological_process | fucose metabolic process |
| D | 0016139 | biological_process | glycoside catabolic process |
| D | 0016787 | molecular_function | hydrolase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 A 501 |
| Chain | Residue |
| A | ARG262 |
| A | ARG271 |
| A | HIS272 |
| A | HOH734 |
| A | HOH645 |
| A | HOH902 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 A 502 |
| Chain | Residue |
| A | LYS196 |
| A | HOH696 |
| site_id | AC3 |
| Number of Residues | 11 |
| Details | binding site for residue 3U3 A 503 |
| Chain | Residue |
| A | GLU87 |
| A | TRP88 |
| A | HIS135 |
| A | HIS136 |
| A | TYR178 |
| A | ASP229 |
| A | ARG262 |
| A | HOH734 |
| A | HOH932 |
| A | HOH660 |
| A | HIS66 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 B 501 |
| Chain | Residue |
| B | LYS90 |
| B | PRO96 |
| B | ALA97 |
| B | HOH619 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 B 502 |
| Chain | Residue |
| B | ARG262 |
| B | ARG271 |
| B | HIS272 |
| B | HOH654 |
| B | HOH749 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 C 501 |
| Chain | Residue |
| C | ARG262 |
| C | ARG271 |
| C | HIS272 |
| C | HOH795 |
| C | HOH749 |
| site_id | AC7 |
| Number of Residues | 17 |
| Details | binding site for Di-peptide 3U3 B 503 and ASP B 229 |
| Chain | Residue |
| B | HIS66 |
| B | GLU87 |
| B | TRP88 |
| B | HIS135 |
| B | HIS136 |
| B | TYR178 |
| B | PHE179 |
| B | SER180 |
| B | VAL181 |
| B | PHE228 |
| B | GLY230 |
| B | THR231 |
| B | TRP232 |
| B | ARG262 |
| B | HOH654 |
| B | HOH634 |
| B | HOH967 |
| site_id | AC8 |
| Number of Residues | 17 |
| Details | binding site for Di-peptide 3U3 C 502 and ASP C 229 |
| Chain | Residue |
| C | HIS66 |
| C | GLU87 |
| C | TRP88 |
| C | HIS135 |
| C | HIS136 |
| C | TYR178 |
| C | PHE179 |
| C | SER180 |
| C | VAL181 |
| C | PHE228 |
| C | GLY230 |
| C | THR231 |
| C | TRP232 |
| C | ARG262 |
| C | TRP316 |
| C | HOH795 |
| C | HOH615 |
| site_id | AC9 |
| Number of Residues | 16 |
| Details | binding site for Di-peptide 3U3 D 501 and ASP D 229 |
| Chain | Residue |
| D | HIS66 |
| D | GLU87 |
| D | TRP88 |
| D | HIS135 |
| D | HIS136 |
| D | TYR178 |
| D | PHE179 |
| D | SER180 |
| D | VAL181 |
| D | PHE228 |
| D | GLY230 |
| D | THR231 |
| D | TRP232 |
| D | ARG262 |
| D | HOH631 |
| D | HOH659 |
