Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004844 | molecular_function | uracil DNA N-glycosylase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006281 | biological_process | DNA repair |
| A | 0006284 | biological_process | base-excision repair |
| A | 0006974 | biological_process | DNA damage response |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0016799 | molecular_function | hydrolase activity, hydrolyzing N-glycosyl compounds |
| A | 0097510 | biological_process | base-excision repair, AP site formation via deaminated base removal |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 11 |
| Details | binding site for residue WBU A 301 |
| Chain | Residue |
| A | GLN67 |
| A | HOH746 |
| A | HOH760 |
| A | ASP68 |
| A | TYR70 |
| A | SER80 |
| A | PHE81 |
| A | ASN127 |
| A | HIS191 |
| A | CIT302 |
| A | EDO304 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | binding site for residue CIT A 302 |
| Chain | Residue |
| A | ASP58 |
| A | THR72 |
| A | PRO91 |
| A | ARG92 |
| A | SER93 |
| A | WBU301 |
| A | HOH422 |
| A | HOH431 |
| A | HOH461 |
| A | HOH485 |
| site_id | AC3 |
| Number of Residues | 15 |
| Details | binding site for residue CIT A 303 |
| Chain | Residue |
| A | GLN67 |
| A | GLY169 |
| A | ARG170 |
| A | LEU195 |
| A | EDO304 |
| A | HOH403 |
| A | HOH413 |
| A | HOH418 |
| A | HOH434 |
| A | HOH435 |
| A | HOH442 |
| A | HOH476 |
| A | HOH512 |
| A | HOH621 |
| A | HOH737 |
| site_id | AC4 |
| Number of Residues | 9 |
| Details | binding site for residue EDO A 304 |
| Chain | Residue |
| A | GLN67 |
| A | HIS191 |
| A | WBU301 |
| A | CIT303 |
| A | HOH403 |
| A | HOH490 |
| A | HOH639 |
| A | HOH737 |
| A | HOH760 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue DMS A 305 |
| Chain | Residue |
| A | ARG41 |
| A | GLY203 |
| A | SER204 |
| A | ARG205 |
| A | ARG209 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue DMS A 306 |
| Chain | Residue |
| A | ILE36 |
| A | ARG41 |
| A | TYR42 |
| A | GLU212 |
| A | HOH472 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | binding site for residue DMS A 307 |
| Chain | Residue |
| A | PRO89 |
| A | TRP90 |
| A | ALA95 |
| A | HOH629 |
| A | HOH630 |
| A | HOH683 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | binding site for residue DMS A 308 |
| Chain | Residue |
| A | THR54 |
| A | PHE55 |
| A | HOH501 |
| A | HOH715 |
| A | HOH761 |
| site_id | AC9 |
| Number of Residues | 1 |
| Details | binding site for residue IPA A 309 |
| site_id | AD1 |
| Number of Residues | 1 |
| Details | binding site for residue CL A 310 |
| site_id | AD2 |
| Number of Residues | 3 |
| Details | binding site for residue CL A 311 |
| Chain | Residue |
| A | ARG41 |
| A | ARG133 |
| A | HOH455 |
Functional Information from PROSITE/UniProt
| site_id | PS00130 |
| Number of Residues | 10 |
| Details | U_DNA_GLYCOSYLASE Uracil-DNA glycosylase signature. RVLIvGQDPY |
| Chain | Residue | Details |
| A | ARG61-TYR70 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"evidenceCode":"ECO:0000250"}]} |
