4WOQ

Crystal Structures of CdNal from Clostridium difficile in complex with ketobutyric

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0005975	biological_process	carbohydrate metabolic process
A	0008747	molecular_function	N-acetylneuraminate lyase activity
A	0016829	molecular_function	lyase activity
A	0019262	biological_process	N-acetylneuraminate catabolic process
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0005975	biological_process	carbohydrate metabolic process
B	0008747	molecular_function	N-acetylneuraminate lyase activity
B	0016829	molecular_function	lyase activity
B	0019262	biological_process	N-acetylneuraminate catabolic process
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0005975	biological_process	carbohydrate metabolic process
C	0008747	molecular_function	N-acetylneuraminate lyase activity
C	0016829	molecular_function	lyase activity
C	0019262	biological_process	N-acetylneuraminate catabolic process
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0005975	biological_process	carbohydrate metabolic process
D	0008747	molecular_function	N-acetylneuraminate lyase activity
D	0016829	molecular_function	lyase activity
D	0019262	biological_process	N-acetylneuraminate catabolic process
E	0005737	cellular_component	cytoplasm
E	0005829	cellular_component	cytosol
E	0005975	biological_process	carbohydrate metabolic process
E	0008747	molecular_function	N-acetylneuraminate lyase activity
E	0016829	molecular_function	lyase activity
E	0019262	biological_process	N-acetylneuraminate catabolic process
F	0005737	cellular_component	cytoplasm
F	0005829	cellular_component	cytosol
F	0005975	biological_process	carbohydrate metabolic process
F	0008747	molecular_function	N-acetylneuraminate lyase activity
F	0016829	molecular_function	lyase activity
F	0019262	biological_process	N-acetylneuraminate catabolic process
G	0005737	cellular_component	cytoplasm
G	0005829	cellular_component	cytosol
G	0005975	biological_process	carbohydrate metabolic process
G	0008747	molecular_function	N-acetylneuraminate lyase activity
G	0016829	molecular_function	lyase activity
G	0019262	biological_process	N-acetylneuraminate catabolic process
H	0005737	cellular_component	cytoplasm
H	0005829	cellular_component	cytosol
H	0005975	biological_process	carbohydrate metabolic process
H	0008747	molecular_function	N-acetylneuraminate lyase activity
H	0016829	molecular_function	lyase activity
H	0019262	biological_process	N-acetylneuraminate catabolic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue 2KT A 401

Chain	Residue
A	TYR182
A	HOH596
A	HOH624
D	THR254

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site_id	AC2
Number of Residues	3
Details	binding site for residue 2KT B 401

Chain	Residue
B	LEU159
B	TYR182
B	ARG186

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site_id	AC3
Number of Residues	2
Details	binding site for residue 2KT C 401

Chain	Residue
C	LEU159
C	TYR182

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site_id	AC4
Number of Residues	3
Details	binding site for residue 2KT D 401

Chain	Residue
D	TYR182
D	LEU183
D	HOH759

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site_id	AC5
Number of Residues	3
Details	binding site for residue 2KT E 401

Chain	Residue
E	SER158
E	LEU159
E	ASP160

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site_id	AC6
Number of Residues	4
Details	binding site for residue 2KT F 401

Chain	Residue
F	LEU159
F	ASP160
F	TYR182
F	HOH657

---

site_id	AC7
Number of Residues	3
Details	binding site for residue 2KT G 401

Chain	Residue
G	LEU159
G	TYR182
G	LEU183

---

site_id	AC8
Number of Residues	3
Details	binding site for residue 2KT H 401

Chain	Residue
H	LEU159
H	LEU183
H	HOH632

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Functional Information from PROSITE/UniProt

site_id	PS00665
Number of Residues	18
Details	DHDPS_1 Dihydrodipicolinate synthase signature 1. GLYvgGSTGENfmlstdE

Chain	Residue	Details
A	GLY52-GLU69

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site_id	PS00666
Number of Residues	31
Details	DHDPS_2 Dihydrodipicolinate synthase signature 2. YSIPflTgvdMsldqfgelfenek.IiGVKFT

Chain	Residue	Details
A	TYR147-THR177

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