4WJZ

Crystal structure of beta-ketoacyl-acyl carrier protein reductase (FabG)(G141A) from Vibrio cholerae

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004316	molecular_function	3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity
A	0006629	biological_process	lipid metabolic process
A	0006631	biological_process	fatty acid metabolic process
A	0006633	biological_process	fatty acid biosynthetic process
A	0016491	molecular_function	oxidoreductase activity
A	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
A	0030497	biological_process	fatty acid elongation
A	0050661	molecular_function	NADP binding
A	0051287	molecular_function	NAD binding
B	0004316	molecular_function	3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity
B	0006629	biological_process	lipid metabolic process
B	0006631	biological_process	fatty acid metabolic process
B	0006633	biological_process	fatty acid biosynthetic process
B	0016491	molecular_function	oxidoreductase activity
B	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
B	0030497	biological_process	fatty acid elongation
B	0050661	molecular_function	NADP binding
B	0051287	molecular_function	NAD binding
C	0004316	molecular_function	3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity
C	0006629	biological_process	lipid metabolic process
C	0006631	biological_process	fatty acid metabolic process
C	0006633	biological_process	fatty acid biosynthetic process
C	0016491	molecular_function	oxidoreductase activity
C	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
C	0030497	biological_process	fatty acid elongation
C	0050661	molecular_function	NADP binding
C	0051287	molecular_function	NAD binding
D	0004316	molecular_function	3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity
D	0006629	biological_process	lipid metabolic process
D	0006631	biological_process	fatty acid metabolic process
D	0006633	biological_process	fatty acid biosynthetic process
D	0016491	molecular_function	oxidoreductase activity
D	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
D	0030497	biological_process	fatty acid elongation
D	0050661	molecular_function	NADP binding
D	0051287	molecular_function	NAD binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	binding site for residue PO4 A 301

Chain	Residue
A	ALA0
A	MET1
A	SER2
A	ARG32
B	SER2
B	ARG32

---

site_id	AC2
Number of Residues	8
Details	binding site for residue PO4 D 301

Chain	Residue
C	ARG32
D	MET1
D	SER2
D	PHE4
D	ARG32
C	ALA0
C	MET1
C	SER2

---

Functional Information from PROSITE/UniProt

site_id	PS00061
Number of Residues	29
Details	ADH_SHORT Short-chain dehydrogenases/reductases family signature. SvvgtmgnagQanYAAAKAGViGFTkSMA

Chain	Residue	Details
A	SER142-ALA170

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	ACT_SITE: Proton acceptor => ECO:0000255|PROSITE-ProRule:PRU10001

Chain	Residue	Details
A	TYR155
B	TYR155
C	TYR155
D	TYR155

---

site_id	SWS_FT_FI2
Number of Residues	28
Details	BINDING: BINDING => ECO:0000250

Chain	Residue	Details
A	GLY16
B	ASN63
B	ASN90
B	SER142
B	TYR155
B	ILE188
C	GLY16
C	THR41
C	ASN63
C	ASN90
C	SER142
A	THR41
C	TYR155
C	ILE188
D	GLY16
D	THR41
D	ASN63
D	ASN90
D	SER142
D	TYR155
D	ILE188
A	ASN63
A	ASN90
A	SER142
A	TYR155
A	ILE188
B	GLY16
B	THR41

---