4WIG

Crystal structure of E47D mutant cytidine deaminase from Mycobacterium tuberculosis (MtCDA E47D)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0004126	molecular_function	cytidine deaminase activity
A	0005829	cellular_component	cytosol
A	0005886	cellular_component	plasma membrane
A	0008270	molecular_function	zinc ion binding
A	0009972	biological_process	cytidine deamination
A	0016787	molecular_function	hydrolase activity
A	0043100	biological_process	pyrimidine nucleobase salvage
A	0046109	biological_process	uridine biosynthetic process
A	0046872	molecular_function	metal ion binding
A	0055086	biological_process	nucleobase-containing small molecule metabolic process
A	0072527	biological_process	pyrimidine-containing compound metabolic process
A	1901135	biological_process	carbohydrate derivative metabolic process
B	0003824	molecular_function	catalytic activity
B	0004126	molecular_function	cytidine deaminase activity
B	0005829	cellular_component	cytosol
B	0005886	cellular_component	plasma membrane
B	0008270	molecular_function	zinc ion binding
B	0009972	biological_process	cytidine deamination
B	0016787	molecular_function	hydrolase activity
B	0043100	biological_process	pyrimidine nucleobase salvage
B	0046109	biological_process	uridine biosynthetic process
B	0046872	molecular_function	metal ion binding
B	0055086	biological_process	nucleobase-containing small molecule metabolic process
B	0072527	biological_process	pyrimidine-containing compound metabolic process
B	1901135	biological_process	carbohydrate derivative metabolic process

Functional Information from PDB Data

Functional Information from PROSITE/UniProt

site_id	PS00903
Number of Residues	41
Details	CYT_DCMP_DEAMINASES_1 Cytidine and deoxycytidylate deaminases zinc-binding region signature. CAEcaVVcalhstgggrllalacvdghgsvlm........PCgr......CrqvL

Chain	Residue	Details
A	CYS56-LEU96

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI3
Number of Residues	6
Details	BINDING: BINDING => ECO:0000269\|PubMed:20035876, ECO:0007744\|PDB:3IJF