4WHB

Crystal structure of phenylurea hydrolase B

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016787	molecular_function	hydrolase activity
A	0016810	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
A	0046872	molecular_function	metal ion binding
B	0016787	molecular_function	hydrolase activity
B	0016810	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
B	0046872	molecular_function	metal ion binding
C	0016787	molecular_function	hydrolase activity
C	0016810	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
C	0046872	molecular_function	metal ion binding
D	0016787	molecular_function	hydrolase activity
D	0016810	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
D	0046872	molecular_function	metal ion binding
E	0016787	molecular_function	hydrolase activity
E	0016810	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
E	0046872	molecular_function	metal ion binding
F	0016787	molecular_function	hydrolase activity
F	0016810	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
F	0046872	molecular_function	metal ion binding
G	0016787	molecular_function	hydrolase activity
G	0016810	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
G	0046872	molecular_function	metal ion binding
H	0016787	molecular_function	hydrolase activity
H	0016810	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
H	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue ZN A 501

Chain	Residue
A	HIS67
A	HIS273
A	ASP344
A	HOH601
A	HOH603

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site_id	AC2
Number of Residues	8
Details	binding site for Di-peptide MET A 73 and ALA A 76

Chain	Residue
A	MET75
A	GLY77
A	GLY79
A	TYR83
A	ASP70
A	ALA71
A	TRP72
A	PHE74

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site_id	AC3
Number of Residues	12
Details	binding site for Di-peptide ILE A 272 and ASN A 342

Chain	Residue
A	GLY64
A	ASN65
A	LYS206
A	THR252
A	LEU271
A	HIS273
A	GLY298
A	GLN300
A	LEU340
A	LEU341
A	THR343
A	TRP375

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site_id	AC4
Number of Residues	15
Details	binding site for Di-peptide LEU F 278 and TYR F 325

Chain	Residue
F	PHE224
F	SER227
F	VAL255
F	ASN275
F	TYR276
F	THR277
F	GLY279
F	GLN280
F	GLU323
F	PRO324
F	ALA326
F	THR327
F	ASN328
F	GLU329
H	LEU184

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