Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0003987 | molecular_function | acetate-CoA ligase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006629 | biological_process | lipid metabolic process |
| A | 0016874 | molecular_function | ligase activity |
| A | 0030729 | molecular_function | acetoacetate-CoA ligase activity |
| A | 0032024 | biological_process | positive regulation of insulin secretion |
| A | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 701 |
| Chain | Residue |
| A | ASP13 |
| A | ALA14 |
| A | GLN15 |
| A | ALA18 |
| A | HOH1171 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 702 |
| Chain | Residue |
| A | EDO703 |
| A | HOH1058 |
| A | HOH1093 |
| A | GLY40 |
| A | TYR41 |
| A | THR436 |
| A | LEU437 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 703 |
| Chain | Residue |
| A | ILE22 |
| A | THR23 |
| A | GLN26 |
| A | TYR41 |
| A | THR436 |
| A | EDO702 |
| A | HOH1022 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 704 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 705 |
| Chain | Residue |
| A | PRO438 |
| A | HIS440 |
| A | ARG515 |
| A | HOH1014 |
| A | HOH1254 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 706 |
| Chain | Residue |
| A | LEU396 |
| A | PHE401 |
| A | SER419 |
| A | VAL439 |
| A | HIS440 |
| A | GLU443 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 707 |
| Chain | Residue |
| A | ALA42 |
| A | PRO447 |
| A | GLY516 |
| A | HOH1015 |
| A | HOH1214 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 708 |
| Chain | Residue |
| A | HIS265 |
| A | PRO266 |
| A | TRP403 |
| A | ASP406 |
| A | GLU407 |
| A | HOH809 |
| A | HOH842 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 709 |
| Chain | Residue |
| A | PHE63 |
| A | HIS96 |
| A | LEU294 |
| A | LEU328 |
| A | HOH869 |
| A | HOH874 |
| site_id | AD1 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 710 |
| Chain | Residue |
| A | GLN130 |
| A | TRP246 |
| site_id | AD2 |
| Number of Residues | 9 |
| Details | binding site for residue EDO A 711 |
| Chain | Residue |
| A | ALA177 |
| A | PRO178 |
| A | ASP179 |
| A | TYR203 |
| A | TYR205 |
| A | SER314 |
| A | EDO712 |
| A | HOH960 |
| A | HOH966 |
| site_id | AD3 |
| Number of Residues | 9 |
| Details | binding site for residue EDO A 712 |
| Chain | Residue |
| A | TYR312 |
| A | THR313 |
| A | SER314 |
| A | TYR336 |
| A | ASP337 |
| A | GLY338 |
| A | EDO711 |
| A | HOH938 |
| A | HOH1119 |
| site_id | AD4 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 713 |
| Chain | Residue |
| A | ARG220 |
| A | VAL229 |
| A | GLY242 |
| A | HOH818 |
| site_id | AD5 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 714 |
| Chain | Residue |
| A | SER421 |
| A | PHE430 |
| A | ALA431 |
| A | ASP508 |
| A | HOH1268 |
| site_id | AD6 |
| Number of Residues | 8 |
| Details | binding site for residue EDO A 715 |
| Chain | Residue |
| A | VAL65 |
| A | ARG66 |
| A | LEU91 |
| A | ASN92 |
| A | GLU95 |
| A | HIS96 |
| A | ARG99 |
| A | HOH1080 |
| site_id | AD7 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 716 |
| Chain | Residue |
| A | ASP77 |
| A | GLY82 |
| A | ASP380 |
| A | CA723 |
| A | HOH803 |
| site_id | AD8 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 717 |
| Chain | Residue |
| A | PHE180 |
| A | ARG188 |
| A | TYR271 |
| A | SER272 |
| A | HOH1025 |
| site_id | AD9 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 718 |
| Chain | Residue |
| A | HOH844 |
| A | HOH895 |
| A | GLU218 |
| A | GLY330 |
| site_id | AE1 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 719 |
| Chain | Residue |
| A | ASP179 |
| A | TYR203 |
| A | TYR205 |
| site_id | AE2 |
| Number of Residues | 8 |
| Details | binding site for residue EDO A 720 |
| Chain | Residue |
| A | GLY102 |
| A | THR103 |
| A | PRO105 |
| A | PHE180 |
| A | GLY181 |
| A | ARG212 |
| A | THR215 |
| A | HOH897 |
| site_id | AE3 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 721 |
| Chain | Residue |
| A | ARG308 |
| A | ASP633 |
| A | PRO638 |
| A | HOH879 |
| site_id | AE4 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 722 |
| Chain | Residue |
| A | GLY341 |
| A | THR345 |
| A | TYR366 |
| A | ALA369 |
| site_id | AE5 |
| Number of Residues | 6 |
| Details | binding site for residue CA A 723 |
| Chain | Residue |
| A | ASP77 |
| A | THR79 |
| A | PRO81 |
| A | GLY82 |
| A | EDO716 |
| A | HOH1294 |
| site_id | AE6 |
| Number of Residues | 6 |
| Details | binding site for residue CA A 724 |
| Chain | Residue |
| A | GLU545 |
| A | LEU547 |
| A | ILE550 |
| A | HOH900 |
| A | HOH1287 |
| A | HOH1288 |
Functional Information from PROSITE/UniProt
| site_id | PS00455 |
| Number of Residues | 12 |
| Details | AMP_BINDING Putative AMP-binding domain signature. VLYSSGTTGlPK |
| Chain | Residue | Details |
| A | VAL269-LYS280 | |
