4W61

Crystal structure of beta-ketoacyl thiolase B (BktB) from Ralstonia eutropha

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003985	molecular_function	acetyl-CoA C-acetyltransferase activity
A	0016746	molecular_function	acyltransferase activity
A	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
B	0003985	molecular_function	acetyl-CoA C-acetyltransferase activity
B	0016746	molecular_function	acyltransferase activity
B	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
C	0003985	molecular_function	acetyl-CoA C-acetyltransferase activity
C	0016746	molecular_function	acyltransferase activity
C	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
D	0003985	molecular_function	acetyl-CoA C-acetyltransferase activity
D	0016746	molecular_function	acyltransferase activity
D	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
E	0003985	molecular_function	acetyl-CoA C-acetyltransferase activity
E	0016746	molecular_function	acyltransferase activity
E	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
F	0003985	molecular_function	acetyl-CoA C-acetyltransferase activity
F	0016746	molecular_function	acyltransferase activity
F	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
G	0003985	molecular_function	acetyl-CoA C-acetyltransferase activity
G	0016746	molecular_function	acyltransferase activity
G	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
H	0003985	molecular_function	acetyl-CoA C-acetyltransferase activity
H	0016746	molecular_function	acyltransferase activity
H	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
I	0003985	molecular_function	acetyl-CoA C-acetyltransferase activity
I	0016746	molecular_function	acyltransferase activity
I	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
J	0003985	molecular_function	acetyl-CoA C-acetyltransferase activity
J	0016746	molecular_function	acyltransferase activity
J	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
K	0003985	molecular_function	acetyl-CoA C-acetyltransferase activity
K	0016746	molecular_function	acyltransferase activity
K	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
L	0003985	molecular_function	acetyl-CoA C-acetyltransferase activity
L	0016746	molecular_function	acyltransferase activity
L	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
M	0003985	molecular_function	acetyl-CoA C-acetyltransferase activity
M	0016746	molecular_function	acyltransferase activity
M	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
N	0003985	molecular_function	acetyl-CoA C-acetyltransferase activity
N	0016746	molecular_function	acyltransferase activity
N	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
O	0003985	molecular_function	acetyl-CoA C-acetyltransferase activity
O	0016746	molecular_function	acyltransferase activity
O	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
P	0003985	molecular_function	acetyl-CoA C-acetyltransferase activity
P	0016746	molecular_function	acyltransferase activity
P	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups

Functional Information from PROSITE/UniProt

site_id	PS00098
Number of Residues	19
Details	THIOLASE_1 Thiolases acyl-enzyme intermediate signature. VNRlCGSGLqAIvsaaqtI

Chain	Residue	Details
A	VAL86-ILE104

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site_id	PS00099
Number of Residues	14
Details	THIOLASE_3 Thiolases active site. ALVTMCIGgGqGiA

Chain	Residue	Details
A	ALA375-ALA388

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	16
Details	ACT_SITE: Acyl-thioester intermediate => ECO:0000250

Chain	Residue	Details
A	CYS90
J	CYS90
K	CYS90
L	CYS90
M	CYS90
N	CYS90
O	CYS90
P	CYS90
B	CYS90
C	CYS90
D	CYS90
E	CYS90
F	CYS90
G	CYS90
H	CYS90
I	CYS90

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site_id	SWS_FT_FI2
Number of Residues	32
Details	ACT_SITE: Proton acceptor => ECO:0000255|PROSITE-ProRule:PRU10020

Chain	Residue	Details
A	HIS350
E	CYS380
F	HIS350
F	CYS380
G	HIS350
G	CYS380
H	HIS350
H	CYS380
I	HIS350
I	CYS380
J	HIS350
A	CYS380
J	CYS380
K	HIS350
K	CYS380
L	HIS350
L	CYS380
M	HIS350
M	CYS380
N	HIS350
N	CYS380
O	HIS350
B	HIS350
O	CYS380
P	HIS350
P	CYS380
B	CYS380
C	HIS350
C	CYS380
D	HIS350
D	CYS380
E	HIS350

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