4VUB

CCDB, A TOPOISOMERASE POISON FROM ESCHERICHIA COLI

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005515	molecular_function	protein binding
A	0006276	biological_process	plasmid maintenance
A	0006351	biological_process	DNA-templated transcription
A	0008657	molecular_function	DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) inhibitor activity
A	0045892	biological_process	negative regulation of DNA-templated transcription
A	2000104	biological_process	negative regulation of DNA-templated DNA replication

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL A 201

Chain	Residue
A	THR7
A	HIS55
A	HIS85
A	ARG86

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site_id	AC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL A 202

Chain	Residue
A	ARG15
A	SER38

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site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CL A 203

Chain	Residue
A	HOH220
A	HOH230
A	HOH230
A	VAL73
A	VAL73
A	HOH220

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