Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

4V94

Molecular architecture of the eukaryotic chaperonin TRiC/CCT derived by a combination of chemical crosslinking and mass-spectrometry, XL-MS

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
a	0000166	molecular_function	nucleotide binding
a	0005515	molecular_function	protein binding
a	0005524	molecular_function	ATP binding
a	0005737	cellular_component	cytoplasm
a	0005832	cellular_component	chaperonin-containing T-complex
a	0005886	cellular_component	plasma membrane
a	0006457	biological_process	protein folding
a	0016887	molecular_function	ATP hydrolysis activity
a	0051082	molecular_function	unfolded protein binding
a	0140662	molecular_function	ATP-dependent protein folding chaperone
A	0000166	molecular_function	nucleotide binding
A	0005515	molecular_function	protein binding
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0005832	cellular_component	chaperonin-containing T-complex
A	0005886	cellular_component	plasma membrane
A	0006457	biological_process	protein folding
A	0016887	molecular_function	ATP hydrolysis activity
A	0051082	molecular_function	unfolded protein binding
A	0140662	molecular_function	ATP-dependent protein folding chaperone
b	0000166	molecular_function	nucleotide binding
b	0005515	molecular_function	protein binding
b	0005524	molecular_function	ATP binding
b	0005737	cellular_component	cytoplasm
b	0005829	cellular_component	cytosol
b	0005832	cellular_component	chaperonin-containing T-complex
b	0006457	biological_process	protein folding
b	0016887	molecular_function	ATP hydrolysis activity
b	0051082	molecular_function	unfolded protein binding
b	0140662	molecular_function	ATP-dependent protein folding chaperone
B	0000166	molecular_function	nucleotide binding
B	0005515	molecular_function	protein binding
B	0005524	molecular_function	ATP binding
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0005832	cellular_component	chaperonin-containing T-complex
B	0006457	biological_process	protein folding
B	0016887	molecular_function	ATP hydrolysis activity
B	0051082	molecular_function	unfolded protein binding
B	0140662	molecular_function	ATP-dependent protein folding chaperone
c	0005524	molecular_function	ATP binding
c	0006457	biological_process	protein folding
c	0016887	molecular_function	ATP hydrolysis activity
c	0051082	molecular_function	unfolded protein binding
c	0140662	molecular_function	ATP-dependent protein folding chaperone
C	0005524	molecular_function	ATP binding
C	0006457	biological_process	protein folding
C	0016887	molecular_function	ATP hydrolysis activity
C	0051082	molecular_function	unfolded protein binding
C	0140662	molecular_function	ATP-dependent protein folding chaperone
d	0000166	molecular_function	nucleotide binding
d	0005515	molecular_function	protein binding
d	0005524	molecular_function	ATP binding
d	0005737	cellular_component	cytoplasm
d	0005832	cellular_component	chaperonin-containing T-complex
d	0006457	biological_process	protein folding
d	0016887	molecular_function	ATP hydrolysis activity
d	0051082	molecular_function	unfolded protein binding
d	0140662	molecular_function	ATP-dependent protein folding chaperone
D	0000166	molecular_function	nucleotide binding
D	0005515	molecular_function	protein binding
D	0005524	molecular_function	ATP binding
D	0005737	cellular_component	cytoplasm
D	0005832	cellular_component	chaperonin-containing T-complex
D	0006457	biological_process	protein folding
D	0016887	molecular_function	ATP hydrolysis activity
D	0051082	molecular_function	unfolded protein binding
D	0140662	molecular_function	ATP-dependent protein folding chaperone
e	0000166	molecular_function	nucleotide binding
e	0005515	molecular_function	protein binding
e	0005524	molecular_function	ATP binding
e	0005737	cellular_component	cytoplasm
e	0005832	cellular_component	chaperonin-containing T-complex
e	0006457	biological_process	protein folding
e	0016887	molecular_function	ATP hydrolysis activity
e	0051082	molecular_function	unfolded protein binding
e	0140662	molecular_function	ATP-dependent protein folding chaperone
E	0000166	molecular_function	nucleotide binding
E	0005515	molecular_function	protein binding
E	0005524	molecular_function	ATP binding
E	0005737	cellular_component	cytoplasm
E	0005832	cellular_component	chaperonin-containing T-complex
E	0006457	biological_process	protein folding
E	0016887	molecular_function	ATP hydrolysis activity
E	0051082	molecular_function	unfolded protein binding
E	0140662	molecular_function	ATP-dependent protein folding chaperone
f	0000166	molecular_function	nucleotide binding
f	0005515	molecular_function	protein binding
f	0005524	molecular_function	ATP binding
f	0005737	cellular_component	cytoplasm
f	0005832	cellular_component	chaperonin-containing T-complex
f	0006457	biological_process	protein folding
f	0016887	molecular_function	ATP hydrolysis activity
f	0051082	molecular_function	unfolded protein binding
f	0140662	molecular_function	ATP-dependent protein folding chaperone
F	0000166	molecular_function	nucleotide binding
F	0005515	molecular_function	protein binding
F	0005524	molecular_function	ATP binding
F	0005737	cellular_component	cytoplasm
F	0005832	cellular_component	chaperonin-containing T-complex
F	0006457	biological_process	protein folding
F	0016887	molecular_function	ATP hydrolysis activity
F	0051082	molecular_function	unfolded protein binding
F	0140662	molecular_function	ATP-dependent protein folding chaperone
g	0000166	molecular_function	nucleotide binding
g	0005524	molecular_function	ATP binding
g	0005737	cellular_component	cytoplasm
g	0005832	cellular_component	chaperonin-containing T-complex
g	0006457	biological_process	protein folding
g	0016887	molecular_function	ATP hydrolysis activity
g	0051082	molecular_function	unfolded protein binding
g	0140662	molecular_function	ATP-dependent protein folding chaperone
G	0000166	molecular_function	nucleotide binding
G	0005524	molecular_function	ATP binding
G	0005737	cellular_component	cytoplasm
G	0005832	cellular_component	chaperonin-containing T-complex
G	0006457	biological_process	protein folding
G	0016887	molecular_function	ATP hydrolysis activity
G	0051082	molecular_function	unfolded protein binding
G	0140662	molecular_function	ATP-dependent protein folding chaperone
h	0000166	molecular_function	nucleotide binding
h	0005515	molecular_function	protein binding
h	0005524	molecular_function	ATP binding
h	0005737	cellular_component	cytoplasm
h	0005832	cellular_component	chaperonin-containing T-complex
h	0006457	biological_process	protein folding
h	0016887	molecular_function	ATP hydrolysis activity
h	0051082	molecular_function	unfolded protein binding
h	0140662	molecular_function	ATP-dependent protein folding chaperone
H	0000166	molecular_function	nucleotide binding
H	0005515	molecular_function	protein binding
H	0005524	molecular_function	ATP binding
H	0005737	cellular_component	cytoplasm
H	0005832	cellular_component	chaperonin-containing T-complex
H	0006457	biological_process	protein folding
H	0016887	molecular_function	ATP hydrolysis activity
H	0051082	molecular_function	unfolded protein binding
H	0140662	molecular_function	ATP-dependent protein folding chaperone
i	0000166	molecular_function	nucleotide binding
i	0005515	molecular_function	protein binding
i	0005524	molecular_function	ATP binding
i	0005737	cellular_component	cytoplasm
i	0005832	cellular_component	chaperonin-containing T-complex
i	0005886	cellular_component	plasma membrane
i	0006457	biological_process	protein folding
i	0016887	molecular_function	ATP hydrolysis activity
i	0051082	molecular_function	unfolded protein binding
i	0140662	molecular_function	ATP-dependent protein folding chaperone
I	0000166	molecular_function	nucleotide binding
I	0005515	molecular_function	protein binding
I	0005524	molecular_function	ATP binding
I	0005737	cellular_component	cytoplasm
I	0005832	cellular_component	chaperonin-containing T-complex
I	0005886	cellular_component	plasma membrane
I	0006457	biological_process	protein folding
I	0016887	molecular_function	ATP hydrolysis activity
I	0051082	molecular_function	unfolded protein binding
I	0140662	molecular_function	ATP-dependent protein folding chaperone
j	0000166	molecular_function	nucleotide binding
j	0005515	molecular_function	protein binding
j	0005524	molecular_function	ATP binding
j	0005737	cellular_component	cytoplasm
j	0005829	cellular_component	cytosol
j	0005832	cellular_component	chaperonin-containing T-complex
j	0006457	biological_process	protein folding
j	0016887	molecular_function	ATP hydrolysis activity
j	0051082	molecular_function	unfolded protein binding
j	0140662	molecular_function	ATP-dependent protein folding chaperone
J	0000166	molecular_function	nucleotide binding
J	0005515	molecular_function	protein binding
J	0005524	molecular_function	ATP binding
J	0005737	cellular_component	cytoplasm
J	0005829	cellular_component	cytosol
J	0005832	cellular_component	chaperonin-containing T-complex
J	0006457	biological_process	protein folding
J	0016887	molecular_function	ATP hydrolysis activity
J	0051082	molecular_function	unfolded protein binding
J	0140662	molecular_function	ATP-dependent protein folding chaperone
k	0005524	molecular_function	ATP binding
k	0006457	biological_process	protein folding
k	0016887	molecular_function	ATP hydrolysis activity
k	0051082	molecular_function	unfolded protein binding
k	0140662	molecular_function	ATP-dependent protein folding chaperone
K	0005524	molecular_function	ATP binding
K	0006457	biological_process	protein folding
K	0016887	molecular_function	ATP hydrolysis activity
K	0051082	molecular_function	unfolded protein binding
K	0140662	molecular_function	ATP-dependent protein folding chaperone
l	0000166	molecular_function	nucleotide binding
l	0005515	molecular_function	protein binding
l	0005524	molecular_function	ATP binding
l	0005737	cellular_component	cytoplasm
l	0005832	cellular_component	chaperonin-containing T-complex
l	0006457	biological_process	protein folding
l	0016887	molecular_function	ATP hydrolysis activity
l	0051082	molecular_function	unfolded protein binding
l	0140662	molecular_function	ATP-dependent protein folding chaperone
L	0000166	molecular_function	nucleotide binding
L	0005515	molecular_function	protein binding
L	0005524	molecular_function	ATP binding
L	0005737	cellular_component	cytoplasm
L	0005832	cellular_component	chaperonin-containing T-complex
L	0006457	biological_process	protein folding
L	0016887	molecular_function	ATP hydrolysis activity
L	0051082	molecular_function	unfolded protein binding
L	0140662	molecular_function	ATP-dependent protein folding chaperone
m	0000166	molecular_function	nucleotide binding
m	0005515	molecular_function	protein binding
m	0005524	molecular_function	ATP binding
m	0005737	cellular_component	cytoplasm
m	0005832	cellular_component	chaperonin-containing T-complex
m	0006457	biological_process	protein folding
m	0016887	molecular_function	ATP hydrolysis activity
m	0051082	molecular_function	unfolded protein binding
m	0140662	molecular_function	ATP-dependent protein folding chaperone
M	0000166	molecular_function	nucleotide binding
M	0005515	molecular_function	protein binding
M	0005524	molecular_function	ATP binding
M	0005737	cellular_component	cytoplasm
M	0005832	cellular_component	chaperonin-containing T-complex
M	0006457	biological_process	protein folding
M	0016887	molecular_function	ATP hydrolysis activity
M	0051082	molecular_function	unfolded protein binding
M	0140662	molecular_function	ATP-dependent protein folding chaperone
n	0000166	molecular_function	nucleotide binding
n	0005515	molecular_function	protein binding
n	0005524	molecular_function	ATP binding
n	0005737	cellular_component	cytoplasm
n	0005832	cellular_component	chaperonin-containing T-complex
n	0006457	biological_process	protein folding
n	0016887	molecular_function	ATP hydrolysis activity
n	0051082	molecular_function	unfolded protein binding
n	0140662	molecular_function	ATP-dependent protein folding chaperone
N	0000166	molecular_function	nucleotide binding
N	0005515	molecular_function	protein binding
N	0005524	molecular_function	ATP binding
N	0005737	cellular_component	cytoplasm
N	0005832	cellular_component	chaperonin-containing T-complex
N	0006457	biological_process	protein folding
N	0016887	molecular_function	ATP hydrolysis activity
N	0051082	molecular_function	unfolded protein binding
N	0140662	molecular_function	ATP-dependent protein folding chaperone
o	0000166	molecular_function	nucleotide binding
o	0005524	molecular_function	ATP binding
o	0005737	cellular_component	cytoplasm
o	0005832	cellular_component	chaperonin-containing T-complex
o	0006457	biological_process	protein folding
o	0016887	molecular_function	ATP hydrolysis activity
o	0051082	molecular_function	unfolded protein binding
o	0140662	molecular_function	ATP-dependent protein folding chaperone
O	0000166	molecular_function	nucleotide binding
O	0005524	molecular_function	ATP binding
O	0005737	cellular_component	cytoplasm
O	0005832	cellular_component	chaperonin-containing T-complex
O	0006457	biological_process	protein folding
O	0016887	molecular_function	ATP hydrolysis activity
O	0051082	molecular_function	unfolded protein binding
O	0140662	molecular_function	ATP-dependent protein folding chaperone
p	0000166	molecular_function	nucleotide binding
p	0005515	molecular_function	protein binding
p	0005524	molecular_function	ATP binding
p	0005737	cellular_component	cytoplasm
p	0005832	cellular_component	chaperonin-containing T-complex
p	0006457	biological_process	protein folding
p	0016887	molecular_function	ATP hydrolysis activity
p	0051082	molecular_function	unfolded protein binding
p	0140662	molecular_function	ATP-dependent protein folding chaperone
P	0000166	molecular_function	nucleotide binding
P	0005515	molecular_function	protein binding
P	0005524	molecular_function	ATP binding
P	0005737	cellular_component	cytoplasm
P	0005832	cellular_component	chaperonin-containing T-complex
P	0006457	biological_process	protein folding
P	0016887	molecular_function	ATP hydrolysis activity
P	0051082	molecular_function	unfolded protein binding
P	0140662	molecular_function	ATP-dependent protein folding chaperone

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue MG F 601

Chain	Residue
F	ASP89
F	THR160
F	LYS161
F	ADP602
F	BEF603

site_id	AC2
Number of Residues	16
Details	binding site for residue ADP F 602

Chain	Residue
F	ASP89
F	GLY90
F	THR91
F	THR92
F	THR93
F	THR160
F	ALA415
F	VAL491
F	LEU493
F	ILE506
F	MG601
F	BEF603
F	ASN36
F	LEU37
F	GLY38
F	PRO39

site_id	AC3
Number of Residues	9
Details	binding site for residue BEF F 603

Chain	Residue
F	ASP58
F	GLY59
F	ASP89
F	GLY90
F	THR91
F	THR92
F	LYS161
F	MG601
F	ADP602

site_id	AC4
Number of Residues	4
Details	binding site for residue MG H 601

Chain	Residue
H	ASP98
H	SER169
H	ADP602
H	BEF603

site_id	AC5
Number of Residues	16
Details	binding site for residue ADP H 602

Chain	Residue
H	MET46
H	GLY47
H	ASP98
H	GLY99
H	THR100
H	ASN101
H	LEU102
H	PRO165
H	SER169
H	GLY422
H	ALA423
H	ILE517
H	ASP519
H	LYS524
H	MG601
H	BEF603

site_id	AC6
Number of Residues	10
Details	binding site for residue BEF H 603

Chain	Residue
H	ASP67
H	GLY97
H	ASP98
H	GLY99
H	THR100
H	ASN101
H	LYS170
H	ASP403
H	MG601
H	ADP602

site_id	AC7
Number of Residues	4
Details	binding site for residue MG G 601

Chain	Residue
G	ASP96
G	LYS169
G	ADP602
G	BEF603

site_id	AC8
Number of Residues	19
Details	binding site for residue ADP G 602

Chain	Residue
G	THR43
G	LEU44
G	GLY45
G	PRO46
G	ASP96
G	GLY97
G	THR98
G	THR99
G	SER100
G	THR164
G	SER167
G	SER168
G	GLY412
G	GLY413
G	VAL481
G	GLU498
G	LYS503
G	MG601
G	BEF603

site_id	AC9
Number of Residues	9
Details	binding site for residue BEF G 603

Chain	Residue
G	ASN64
G	ASP65
G	ASP96
G	THR98
G	THR99
G	LYS169
G	ASP395
G	MG601
G	ADP602

site_id	AD1
Number of Residues	4
Details	binding site for residue MG E 601

Chain	Residue
E	ASP117
E	SER187
E	ADP602
E	BEF603

site_id	AD2
Number of Residues	19
Details	binding site for residue ADP E 602

Chain	Residue
E	ASN85
E	ASP117
E	GLY118
E	THR119
E	THR120
E	GLY121
E	SER190
E	GLY442
E	GLY443
E	LEU483
E	VAL512
E	CYS514
E	VAL527
E	ASP529
E	MG601
E	BEF603
E	SER64
E	GLY66
E	PRO67

site_id	AD3
Number of Residues	9
Details	binding site for residue BEF E 603

Chain	Residue
E	ASN85
E	ASP86
E	ASP117
E	GLY118
E	THR119
E	THR120
E	LYS191
E	MG601
E	ADP602

site_id	AD4
Number of Residues	3
Details	binding site for residue MG B 601

Chain	Residue
B	ASP90
B	ADP602
B	BEF603

site_id	AD5
Number of Residues	23
Details	binding site for residue ADP B 602

Chain	Residue
B	THR36
B	LEU37
B	GLY38
B	PRO39
B	ASN58
B	ASP90
B	GLY91
B	THR92
B	THR93
B	SER94
B	THR159
B	SER162
B	SER163
B	GLY403
B	GLY404
B	GLU408
B	LEU444
B	LEU472
B	ILE487
B	GLU489
B	LYS494
B	MG601
B	BEF603

site_id	AD6
Number of Residues	9
Details	binding site for residue BEF B 603

Chain	Residue
B	THR36
B	ASN58
B	ASP59
B	ASP90
B	THR92
B	THR93
B	LYS164
B	MG601
B	ADP602

site_id	AD7
Number of Residues	4
Details	binding site for residue MG D 601

Chain	Residue
D	ASP91
D	LYS161
D	ADP602
D	BEF603

site_id	AD8
Number of Residues	20
Details	binding site for residue ADP D 602

Chain	Residue
D	SER38
D	LEU39
D	GLY40
D	PRO41
D	ASN59
D	ASP91
D	GLY92
D	THR93
D	THR94
D	SER95
D	THR156
D	SER160
D	GLY414
D	LEU454
D	ILE482
D	VAL484
D	ILE497
D	GLN499
D	MG601
D	BEF603

site_id	AD9
Number of Residues	9
Details	binding site for residue BEF D 603

Chain	Residue
D	ASN59
D	ASP60
D	ASP91
D	GLY92
D	THR93
D	THR94
D	LYS161
D	MG601
D	ADP602

site_id	AE1
Number of Residues	3
Details	binding site for residue MG A 601

Chain	Residue
A	ASP96
A	ADP602
A	BEF603

site_id	AE2
Number of Residues	18
Details	binding site for residue ADP A 602

Chain	Residue
A	SER43
A	LEU44
A	GLY45
A	ASP96
A	GLY97
A	THR98
A	THR99
A	SER100
A	THR162
A	SER165
A	SER166
A	GLY422
A	GLY423
A	LEU502
A	VAL517
A	GLU519
A	MG601
A	BEF603

site_id	AE3
Number of Residues	10
Details	binding site for residue BEF A 603

Chain	Residue
A	ASN64
A	ASP65
A	ASP96
A	GLY97
A	THR98
A	THR99
A	LYS167
A	ASP404
A	MG601
A	ADP602

site_id	AE4
Number of Residues	3
Details	binding site for residue MG C 1101

Chain	Residue
C	ASP91
C	ADP1102
C	BEF1103

site_id	AE5
Number of Residues	18
Details	binding site for residue ADP C 1102

Chain	Residue
C	CYS38
C	LEU39
C	GLY40
C	PRO41
C	ASP91
C	GLY92
C	THR93
C	THR94
C	THR95
C	THR161
C	GLY415
C	GLY416
C	ILE484
C	GLY486
C	ILE499
C	GLU501
C	MG1101
C	BEF1103

site_id	AE6
Number of Residues	9
Details	binding site for residue BEF C 1103

Chain	Residue
C	ASN59
C	ASP60
C	GLY61
C	ASP91
C	THR93
C	THR94
C	LYS162
C	MG1101
C	ADP1102

site_id	AE7
Number of Residues	4
Details	binding site for residue MG N 601

Chain	Residue
N	ASP89
N	THR160
N	ADP602
N	BEF603

site_id	AE8
Number of Residues	18
Details	binding site for residue ADP N 602

Chain	Residue
N	ASN36
N	LEU37
N	GLY38
N	ASP89
N	GLY90
N	THR91
N	THR92
N	THR93
N	THR160
N	ALA415
N	GLY416
N	LEU458
N	VAL491
N	LEU493
N	ILE506
N	ASP508
N	MG601
N	BEF603

site_id	AE9
Number of Residues	9
Details	binding site for residue BEF N 603

Chain	Residue
N	ASP58
N	GLY59
N	ASP89
N	GLY90
N	THR91
N	THR92
N	LYS161
N	MG601
N	ADP602

site_id	AF1
Number of Residues	3
Details	binding site for residue MG P 601

Chain	Residue
P	ASP98
P	ADP602
P	BEF603

site_id	AF2
Number of Residues	17
Details	binding site for residue ADP P 602

Chain	Residue
P	MET46
P	GLY47
P	ASN66
P	ASP98
P	GLY99
P	THR100
P	ASN101
P	LEU102
P	PRO165
P	SER169
P	GLY422
P	ALA423
P	ILE517
P	ASP519
P	LYS524
P	MG601
P	BEF603

site_id	AF3
Number of Residues	10
Details	binding site for residue BEF P 603

Chain	Residue
P	ALA68
P	GLY97
P	ASP98
P	GLY99
P	THR100
P	ASN101
P	LYS170
P	ASP403
P	MG601
P	ADP602

site_id	AF4
Number of Residues	3
Details	binding site for residue MG O 601

Chain	Residue
O	ASP96
O	ADP602
O	BEF603

site_id	AF5
Number of Residues	18
Details	binding site for residue ADP O 602

Chain	Residue
O	THR43
O	LEU44
O	GLY45
O	ASP96
O	GLY97
O	THR98
O	THR99
O	SER100
O	THR164
O	SER167
O	SER168
O	GLY413
O	GLY414
O	VAL481
O	GLU498
O	LYS503
O	MG601
O	BEF603

site_id	AF6
Number of Residues	10
Details	binding site for residue BEF O 603

Chain	Residue
O	ASN64
O	ASP65
O	GLY66
O	ASP96
O	THR98
O	THR99
O	LYS169
O	ASP395
O	MG601
O	ADP602

site_id	AF7
Number of Residues	3
Details	binding site for residue MG M 601

Chain	Residue
M	ASP117
M	ADP602
M	BEF603

site_id	AF8
Number of Residues	19
Details	binding site for residue ADP M 602

Chain	Residue
M	SER64
M	LEU65
M	GLY66
M	PRO67
M	ASN85
M	ASP117
M	GLY118
M	THR119
M	THR120
M	GLY121
M	SER190
M	GLY442
M	GLY443
M	VAL512
M	LEU515
M	VAL527
M	ASP529
M	MG601
M	BEF603

site_id	AF9
Number of Residues	10
Details	binding site for residue BEF M 603

Chain	Residue
M	ASN85
M	ASP86
M	ASP117
M	GLY118
M	THR119
M	THR120
M	LYS191
M	ASP425
M	MG601
M	ADP602

site_id	AG1
Number of Residues	3
Details	binding site for residue MG J 601

Chain	Residue
J	ASP90
J	ADP602
J	BEF603

site_id	AG2
Number of Residues	21
Details	binding site for residue ADP J 602

Chain	Residue
J	THR36
J	LEU37
J	GLY38
J	PRO39
J	ASP90
J	GLY91
J	THR92
J	THR93
J	SER94
J	THR159
J	SER162
J	SER163
J	GLY403
J	GLY404
J	GLY405
J	LEU444
J	LEU472
J	GLU489
J	LYS494
J	MG601
J	BEF603

site_id	AG3
Number of Residues	10
Details	binding site for residue BEF J 603

Chain	Residue
J	THR36
J	ASN58
J	ASP59
J	GLY60
J	ASP90
J	THR92
J	THR93
J	LYS164
J	MG601
J	ADP602

site_id	AG4
Number of Residues	5
Details	binding site for residue MG L 601

Chain	Residue
L	ASP91
L	SER157
L	LYS161
L	ADP602
L	BEF603

site_id	AG5
Number of Residues	20
Details	binding site for residue ADP L 602

Chain	Residue
L	SER38
L	LEU39
L	GLY40
L	PRO41
L	ASN59
L	ASP91
L	GLY92
L	THR93
L	THR94
L	SER95
L	THR156
L	SER160
L	GLY414
L	LEU454
L	ILE482
L	VAL484
L	ILE497
L	GLN499
L	MG601
L	BEF603

site_id	AG6
Number of Residues	11
Details	binding site for residue BEF L 603

Chain	Residue
L	ASN59
L	ASP60
L	GLY61
L	ASP91
L	GLY92
L	THR93
L	THR94
L	LYS161
L	ASP396
L	MG601
L	ADP602

site_id	AG7
Number of Residues	5
Details	binding site for residue MG I 601

Chain	Residue
I	ASP96
I	SER163
I	LYS167
I	ADP602
I	BEF603

site_id	AG8
Number of Residues	20
Details	binding site for residue ADP I 602

Chain	Residue
I	SER43
I	LEU44
I	GLY45
I	PRO46
I	ASP96
I	GLY97
I	THR98
I	THR99
I	SER100
I	THR162
I	SER165
I	SER166
I	GLY421
I	GLY422
I	LEU502
I	GLU512
I	GLU519
I	LYS524
I	MG601
I	BEF603

site_id	AG9
Number of Residues	9
Details	binding site for residue BEF I 603

Chain	Residue
I	ASN64
I	ASP65
I	ASP96
I	THR98
I	THR99
I	LYS167
I	ASP404
I	MG601
I	ADP602

site_id	AH1
Number of Residues	3
Details	binding site for residue MG K 1101

Chain	Residue
K	ASP91
K	ADP1102
K	BEF1103

site_id	AH2
Number of Residues	19
Details	binding site for residue ADP K 1102

Chain	Residue
K	CYS38
K	LEU39
K	GLY40
K	PRO41
K	ASP91
K	GLY92
K	THR93
K	THR94
K	THR95
K	THR161
K	GLY416
K	GLY417
K	ILE484
K	GLY486
K	TYR497
K	ILE499
K	GLU501
K	MG1101
K	BEF1103

site_id	AH3
Number of Residues	9
Details	binding site for residue BEF K 1103

Chain	Residue
K	ASN59
K	ASP60
K	GLY61
K	ASP91
K	THR93
K	THR94
K	LYS162
K	MG1101
K	ADP1102

site_id	AH4
Number of Residues	5
Details	binding site for residue MG f 601

Chain	Residue
f	ASP89
f	THR160
f	LYS161
f	ADP602
f	BEF603

site_id	AH5
Number of Residues	19
Details	binding site for residue ADP f 602

Chain	Residue
f	ASN36
f	LEU37
f	GLY38
f	PRO39
f	ASP89
f	GLY90
f	THR91
f	THR92
f	THR93
f	THR160
f	GLY414
f	ALA415
f	LEU458
f	VAL491
f	LEU493
f	ILE506
f	ASP508
f	MG601
f	BEF603

site_id	AH6
Number of Residues	9
Details	binding site for residue BEF f 603

Chain	Residue
f	ASP58
f	GLY59
f	ASP89
f	THR91
f	THR92
f	LYS161
f	ASP397
f	MG601
f	ADP602

site_id	AH7
Number of Residues	4
Details	binding site for residue MG h 601

Chain	Residue
h	ASP98
h	SER169
h	ADP602
h	BEF603

site_id	AH8
Number of Residues	14
Details	binding site for residue ADP h 602

Chain	Residue
h	GLY47
h	ASN66
h	ASP98
h	GLY99
h	THR100
h	ASN101
h	LEU102
h	SER169
h	GLY422
h	ALA423
h	ILE517
h	ASP519
h	MG601
h	BEF603

site_id	AH9
Number of Residues	9
Details	binding site for residue BEF h 603

Chain	Residue
h	GLY97
h	ASP98
h	GLY99
h	THR100
h	ASN101
h	LYS170
h	ASP403
h	MG601
h	ADP602

site_id	AI1
Number of Residues	5
Details	binding site for residue MG g 601

Chain	Residue
g	ASP96
g	ALA165
g	LYS169
g	ADP602
g	BEF603

site_id	AI2
Number of Residues	17
Details	binding site for residue ADP g 602

Chain	Residue
g	THR43
g	LEU44
g	GLY45
g	ASP96
g	GLY97
g	THR98
g	THR99
g	SER100
g	THR164
g	SER167
g	SER168
g	GLY413
g	VAL481
g	GLU498
g	LYS503
g	MG601
g	BEF603

site_id	AI3
Number of Residues	10
Details	binding site for residue BEF g 603

Chain	Residue
g	ASN64
g	ASP65
g	GLY66
g	ASP96
g	THR98
g	THR99
g	LYS169
g	ASP395
g	MG601
g	ADP602

site_id	AI4
Number of Residues	4
Details	binding site for residue MG e 601

Chain	Residue
e	ASP117
e	SER187
e	ADP602
e	BEF603

site_id	AI5
Number of Residues	18
Details	binding site for residue ADP e 602

Chain	Residue
e	SER64
e	LEU65
e	GLY66
e	ASN85
e	ASP117
e	GLY118
e	THR119
e	THR120
e	GLY121
e	THR186
e	SER190
e	GLY442
e	GLY443
e	VAL512
e	VAL527
e	ASP529
e	MG601
e	BEF603

site_id	AI6
Number of Residues	9
Details	binding site for residue BEF e 603

Chain	Residue
e	ASN85
e	ASP86
e	ASP117
e	THR119
e	THR120
e	LYS191
e	ASP425
e	MG601
e	ADP602

site_id	AI7
Number of Residues	4
Details	binding site for residue MG b 601

Chain	Residue
b	ASP90
b	THR160
b	ADP602
b	BEF603

site_id	AI8
Number of Residues	21
Details	binding site for residue ADP b 602

Chain	Residue
b	THR36
b	LEU37
b	GLY38
b	PRO39
b	ASP90
b	GLY91
b	THR92
b	THR93
b	SER94
b	THR159
b	SER162
b	SER163
b	GLY403
b	GLY404
b	LEU444
b	LEU472
b	ILE487
b	GLU489
b	LYS494
b	MG601
b	BEF603

site_id	AI9
Number of Residues	10
Details	binding site for residue BEF b 603

Chain	Residue
b	THR36
b	ASN58
b	ASP59
b	ASP90
b	GLY91
b	THR92
b	THR93
b	LYS164
b	MG601
b	ADP602

site_id	AJ1
Number of Residues	5
Details	binding site for residue MG d 601

Chain	Residue
d	ASP91
d	SER157
d	LYS161
d	ADP602
d	BEF603

site_id	AJ2
Number of Residues	18
Details	binding site for residue ADP d 602

Chain	Residue
d	SER38
d	LEU39
d	GLY40
d	PRO41
d	ASN59
d	ASP91
d	GLY92
d	THR93
d	THR94
d	SER95
d	SER160
d	GLY414
d	ILE482
d	VAL484
d	ILE497
d	GLN499
d	MG601
d	BEF603

site_id	AJ3
Number of Residues	10
Details	binding site for residue BEF d 603

Chain	Residue
d	ASN59
d	ASP60
d	ASP91
d	GLY92
d	THR93
d	THR94
d	LYS161
d	ASP396
d	MG601
d	ADP602

site_id	AJ4
Number of Residues	3
Details	binding site for residue MG a 601

Chain	Residue
a	ASP96
a	ADP602
a	BEF603

site_id	AJ5
Number of Residues	18
Details	binding site for residue ADP a 602

Chain	Residue
a	SER43
a	LEU44
a	GLY45
a	ASP96
a	GLY97
a	THR98
a	THR99
a	SER100
a	THR162
a	SER165
a	SER166
a	GLY422
a	LEU462
a	LEU502
a	GLU512
a	VAL517
a	MG601
a	BEF603

site_id	AJ6
Number of Residues	11
Details	binding site for residue BEF a 603

Chain	Residue
a	ASN64
a	ASP65
a	GLY66
a	ASP96
a	GLY97
a	THR98
a	THR99
a	LYS167
a	ASP404
a	MG601
a	ADP602

site_id	AJ7
Number of Residues	3
Details	binding site for residue MG c 1101

Chain	Residue
c	ASP91
c	ADP1102
c	BEF1103

site_id	AJ8
Number of Residues	17
Details	binding site for residue ADP c 1102

Chain	Residue
c	CYS38
c	LEU39
c	GLY40
c	PRO41
c	ASP91
c	GLY92
c	THR93
c	THR94
c	THR95
c	THR161
c	GLY416
c	ILE484
c	GLY486
c	TYR497
c	GLU501
c	MG1101
c	BEF1103

site_id	AJ9
Number of Residues	10
Details	binding site for residue BEF c 1103

Chain	Residue
c	ASN59
c	ASP60
c	GLY61
c	ASP91
c	THR93
c	THR94
c	LYS162
c	ASP398
c	MG1101
c	ADP1102

site_id	AK1
Number of Residues	5
Details	binding site for residue MG n 601

Chain	Residue
n	ASP89
n	THR160
n	LYS161
n	ADP602
n	BEF603

site_id	AK2
Number of Residues	17
Details	binding site for residue ADP n 602

Chain	Residue
n	ASN36
n	LEU37
n	GLY38
n	PRO39
n	ASP89
n	GLY90
n	THR91
n	THR92
n	THR93
n	THR160
n	GLY414
n	ALA415
n	VAL491
n	LEU493
n	ASP508
n	MG601
n	BEF603

site_id	AK3
Number of Residues	10
Details	binding site for residue BEF n 603

Chain	Residue
n	ASP58
n	GLY59
n	ASP89
n	GLY90
n	THR91
n	THR92
n	LYS161
n	ASP397
n	MG601
n	ADP602

site_id	AK4
Number of Residues	3
Details	binding site for residue MG p 601

Chain	Residue
p	ASP98
p	ADP602
p	BEF603

site_id	AK5
Number of Residues	17
Details	binding site for residue ADP p 602

Chain	Residue
p	MET46
p	GLY47
p	PRO48
p	ASP98
p	GLY99
p	THR100
p	ASN101
p	LEU102
p	PRO165
p	SER169
p	GLY422
p	ALA423
p	ILE517
p	ASP519
p	LYS524
p	MG601
p	BEF603

site_id	AK6
Number of Residues	11
Details	binding site for residue BEF p 603

Chain	Residue
p	ASP67
p	ALA68
p	GLY97
p	ASP98
p	GLY99
p	THR100
p	ASN101
p	LYS170
p	ASP403
p	MG601
p	ADP602

site_id	AK7
Number of Residues	4
Details	binding site for residue MG o 601

Chain	Residue
o	ASP96
o	LYS169
o	ADP602
o	BEF603

site_id	AK8
Number of Residues	18
Details	binding site for residue ADP o 602

Chain	Residue
o	THR43
o	LEU44
o	GLY45
o	ASP96
o	GLY97
o	THR98
o	THR99
o	SER100
o	THR164
o	SER167
o	SER168
o	GLY413
o	VAL481
o	VAL496
o	GLU498
o	LYS503
o	MG601
o	BEF603

site_id	AK9
Number of Residues	11
Details	binding site for residue BEF o 603

Chain	Residue
o	ASN64
o	ASP65
o	GLY66
o	GLY95
o	ASP96
o	THR98
o	THR99
o	LYS169
o	ASP395
o	MG601
o	ADP602

site_id	AL1
Number of Residues	5
Details	binding site for residue MG m 601

Chain	Residue
m	ASP117
m	SER187
m	LYS191
m	ADP602
m	BEF603

site_id	AL2
Number of Residues	18
Details	binding site for residue ADP m 602

Chain	Residue
m	SER64
m	LEU65
m	GLY66
m	ASN85
m	ASP117
m	GLY118
m	THR119
m	THR120
m	GLY121
m	SER190
m	GLY442
m	GLY443
m	LEU483
m	VAL512
m	VAL527
m	ASP529
m	MG601
m	BEF603

site_id	AL3
Number of Residues	10
Details	binding site for residue BEF m 603

Chain	Residue
m	ASN85
m	ASP86
m	ASP117
m	GLY118
m	THR119
m	THR120
m	LYS191
m	ASP425
m	MG601
m	ADP602

site_id	AL4
Number of Residues	4
Details	binding site for residue MG j 601

Chain	Residue
j	ASP90
j	THR160
j	ADP602
j	BEF603

site_id	AL5
Number of Residues	23
Details	binding site for residue ADP j 602

Chain	Residue
j	THR36
j	LEU37
j	GLY38
j	PRO39
j	ASP90
j	GLY91
j	THR92
j	THR93
j	SER94
j	THR159
j	SER162
j	SER163
j	GLY403
j	GLY404
j	GLY405
j	GLU408
j	LEU444
j	LEU472
j	ILE487
j	GLU489
j	LYS494
j	MG601
j	BEF603

site_id	AL6
Number of Residues	9
Details	binding site for residue BEF j 603

Chain	Residue
j	THR36
j	ASN58
j	ASP59
j	ASP90
j	THR92
j	THR93
j	LYS164
j	MG601
j	ADP602

site_id	AL7
Number of Residues	3
Details	binding site for residue MG l 601

Chain	Residue
l	ASP91
l	ADP602
l	BEF603

site_id	AL8
Number of Residues	20
Details	binding site for residue ADP l 602

Chain	Residue
l	SER38
l	LEU39
l	GLY40
l	PRO41
l	ASN59
l	ASP91
l	GLY92
l	THR93
l	THR94
l	SER95
l	THR156
l	SER160
l	GLY414
l	LEU454
l	ILE482
l	VAL484
l	ILE497
l	GLN499
l	MG601
l	BEF603

site_id	AL9
Number of Residues	9
Details	binding site for residue BEF l 603

Chain	Residue
l	ASN59
l	ASP60
l	ASP91
l	GLY92
l	THR93
l	THR94
l	LYS161
l	MG601
l	ADP602

site_id	AM1
Number of Residues	4
Details	binding site for residue MG i 601

Chain	Residue
i	ASP96
i	SER163
i	ADP602
i	BEF603

site_id	AM2
Number of Residues	19
Details	binding site for residue ADP i 602

Chain	Residue
i	SER43
i	LEU44
i	GLY45
i	ASP96
i	GLY97
i	THR98
i	THR99
i	SER100
i	THR162
i	SER165
i	SER166
i	GLY422
i	GLY423
i	LEU502
i	VAL517
i	GLU519
i	LYS524
i	MG601
i	BEF603

site_id	AM3
Number of Residues	11
Details	binding site for residue BEF i 603

Chain	Residue
i	ASN64
i	ASP65
i	GLY66
i	ASP96
i	GLY97
i	THR98
i	THR99
i	LYS167
i	ASP404
i	MG601
i	ADP602

site_id	AM4
Number of Residues	5
Details	binding site for residue MG k 1101

Chain	Residue
k	ADP1102
k	BEF1103
k	ASP91
k	SER158
k	THR161

site_id	AM5
Number of Residues	16
Details	binding site for residue ADP k 1102

Chain	Residue
k	CYS38
k	LEU39
k	GLY40
k	ASP91
k	GLY92
k	THR93
k	THR94
k	THR95
k	THR161
k	GLY416
k	ILE484
k	GLY486
k	ILE499
k	GLU501
k	MG1101
k	BEF1103

site_id	AM6
Number of Residues	10
Details	binding site for residue BEF k 1103

Chain	Residue
k	ASN59
k	ASP60
k	GLY61
k	ASP91
k	THR93
k	THR94
k	LYS162
k	ASP398
k	MG1101
k	ADP1102

Functional Information from PROSITE/UniProt

site_id	PS00107
Number of Residues	34
Details	PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. VGDGTTSVTIlAgelmkeakpfleegisshLIMK

Chain	Residue	Details
o	VAL94-LYS127

site_id	PS00750
Number of Residues	13
Details	TCP1_1 Chaperonins TCP-1 signature 1. KTsLGPrGldKIL

Chain	Residue	Details
m	LYS62-LEU74
k	ARG36-LEU48
F	GLU34-LEU46
l	ARG36-ILE48
j	LYS34-LEU46
H	LEU43-ILE55
i	LYS41-LEU53

site_id	PS00751
Number of Residues	17
Details	TCP1_2 Chaperonins TCP-1 signature 2. LTNDGHAILreIdVaHP

Chain	Residue	Details
k	LEU57-PRO73
F	LEU55-PRO71
o	ILE62-PRO78
l	ILE57-PRO73
j	VAL56-PRO72
H	ILE64-PRO80
i	VAL62-PRO78

site_id	PS00995
Number of Residues	9
Details	TCP1_3 Chaperonins TCP-1 signature 3. QDdeIGDGT

Chain	Residue	Details
m	GLN111-THR119
k	GLN85-THR93
F	GLN83-THR91
o	GLN90-THR98
l	GLN85-THR93
j	GLN84-THR92
H	GLN92-THR100
i	GLN90-THR98

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	Modified residue: {"description":"N-acetylserine","evidences":[{"source":"PubMed","id":"22814378","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	4
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18407956","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	8
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"19779198","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	8
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"PubMed","id":"12872131","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)