Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

4V46

Crystal structure of the BAFF-BAFF-R complex

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
A0	0005164	molecular_function	tumor necrosis factor receptor binding
A0	0006955	biological_process	immune response
A0	0016020	cellular_component	membrane
A1	0005164	molecular_function	tumor necrosis factor receptor binding
A1	0006955	biological_process	immune response
A1	0016020	cellular_component	membrane
A2	0005164	molecular_function	tumor necrosis factor receptor binding
A2	0006955	biological_process	immune response
A2	0016020	cellular_component	membrane
A3	0005164	molecular_function	tumor necrosis factor receptor binding
A3	0006955	biological_process	immune response
A3	0016020	cellular_component	membrane
A4	0005164	molecular_function	tumor necrosis factor receptor binding
A4	0006955	biological_process	immune response
A4	0016020	cellular_component	membrane
A5	0005164	molecular_function	tumor necrosis factor receptor binding
A5	0006955	biological_process	immune response
A5	0016020	cellular_component	membrane
A6	0005164	molecular_function	tumor necrosis factor receptor binding
A6	0006955	biological_process	immune response
A6	0016020	cellular_component	membrane
A7	0005164	molecular_function	tumor necrosis factor receptor binding
A7	0006955	biological_process	immune response
A7	0016020	cellular_component	membrane
A8	0005164	molecular_function	tumor necrosis factor receptor binding
A8	0006955	biological_process	immune response
A8	0016020	cellular_component	membrane
A9	0005164	molecular_function	tumor necrosis factor receptor binding
A9	0006955	biological_process	immune response
A9	0016020	cellular_component	membrane
Aa	0005164	molecular_function	tumor necrosis factor receptor binding
Aa	0006955	biological_process	immune response
Aa	0016020	cellular_component	membrane
AA	0005164	molecular_function	tumor necrosis factor receptor binding
AA	0006955	biological_process	immune response
AA	0016020	cellular_component	membrane
Ab	0005164	molecular_function	tumor necrosis factor receptor binding
Ab	0006955	biological_process	immune response
Ab	0016020	cellular_component	membrane
AB	0005164	molecular_function	tumor necrosis factor receptor binding
AB	0006955	biological_process	immune response
AB	0016020	cellular_component	membrane
Ac	0005164	molecular_function	tumor necrosis factor receptor binding
Ac	0006955	biological_process	immune response
Ac	0016020	cellular_component	membrane
AC	0005164	molecular_function	tumor necrosis factor receptor binding
AC	0006955	biological_process	immune response
AC	0016020	cellular_component	membrane
Ad	0005164	molecular_function	tumor necrosis factor receptor binding
Ad	0006955	biological_process	immune response
Ad	0016020	cellular_component	membrane
AD	0005164	molecular_function	tumor necrosis factor receptor binding
AD	0006955	biological_process	immune response
AD	0016020	cellular_component	membrane
Ae	0005164	molecular_function	tumor necrosis factor receptor binding
Ae	0006955	biological_process	immune response
Ae	0016020	cellular_component	membrane
AE	0005164	molecular_function	tumor necrosis factor receptor binding
AE	0006955	biological_process	immune response
AE	0016020	cellular_component	membrane
Af	0005164	molecular_function	tumor necrosis factor receptor binding
Af	0006955	biological_process	immune response
Af	0016020	cellular_component	membrane
AF	0005164	molecular_function	tumor necrosis factor receptor binding
AF	0006955	biological_process	immune response
AF	0016020	cellular_component	membrane
Ag	0005164	molecular_function	tumor necrosis factor receptor binding
Ag	0006955	biological_process	immune response
Ag	0016020	cellular_component	membrane
AG	0005164	molecular_function	tumor necrosis factor receptor binding
AG	0006955	biological_process	immune response
AG	0016020	cellular_component	membrane
Ah	0005164	molecular_function	tumor necrosis factor receptor binding
Ah	0006955	biological_process	immune response
Ah	0016020	cellular_component	membrane
AH	0005164	molecular_function	tumor necrosis factor receptor binding
AH	0006955	biological_process	immune response
AH	0016020	cellular_component	membrane
Ai	0005164	molecular_function	tumor necrosis factor receptor binding
Ai	0006955	biological_process	immune response
Ai	0016020	cellular_component	membrane
AI	0005164	molecular_function	tumor necrosis factor receptor binding
AI	0006955	biological_process	immune response
AI	0016020	cellular_component	membrane
Aj	0005164	molecular_function	tumor necrosis factor receptor binding
Aj	0006955	biological_process	immune response
Aj	0016020	cellular_component	membrane
AJ	0005164	molecular_function	tumor necrosis factor receptor binding
AJ	0006955	biological_process	immune response
AJ	0016020	cellular_component	membrane
Ak	0005164	molecular_function	tumor necrosis factor receptor binding
Ak	0006955	biological_process	immune response
Ak	0016020	cellular_component	membrane
AK	0005164	molecular_function	tumor necrosis factor receptor binding
AK	0006955	biological_process	immune response
AK	0016020	cellular_component	membrane
Al	0005164	molecular_function	tumor necrosis factor receptor binding
Al	0006955	biological_process	immune response
Al	0016020	cellular_component	membrane
AL	0005164	molecular_function	tumor necrosis factor receptor binding
AL	0006955	biological_process	immune response
AL	0016020	cellular_component	membrane
Am	0005164	molecular_function	tumor necrosis factor receptor binding
Am	0006955	biological_process	immune response
Am	0016020	cellular_component	membrane
AM	0005164	molecular_function	tumor necrosis factor receptor binding
AM	0006955	biological_process	immune response
AM	0016020	cellular_component	membrane
An	0005164	molecular_function	tumor necrosis factor receptor binding
An	0006955	biological_process	immune response
An	0016020	cellular_component	membrane
AN	0005164	molecular_function	tumor necrosis factor receptor binding
AN	0006955	biological_process	immune response
AN	0016020	cellular_component	membrane
Ao	0005164	molecular_function	tumor necrosis factor receptor binding
Ao	0006955	biological_process	immune response
Ao	0016020	cellular_component	membrane
AO	0005164	molecular_function	tumor necrosis factor receptor binding
AO	0006955	biological_process	immune response
AO	0016020	cellular_component	membrane
Ap	0005164	molecular_function	tumor necrosis factor receptor binding
Ap	0006955	biological_process	immune response
Ap	0016020	cellular_component	membrane
AP	0005164	molecular_function	tumor necrosis factor receptor binding
AP	0006955	biological_process	immune response
AP	0016020	cellular_component	membrane
Aq	0005164	molecular_function	tumor necrosis factor receptor binding
Aq	0006955	biological_process	immune response
Aq	0016020	cellular_component	membrane
AQ	0005164	molecular_function	tumor necrosis factor receptor binding
AQ	0006955	biological_process	immune response
AQ	0016020	cellular_component	membrane
Ar	0005164	molecular_function	tumor necrosis factor receptor binding
Ar	0006955	biological_process	immune response
Ar	0016020	cellular_component	membrane
AR	0005164	molecular_function	tumor necrosis factor receptor binding
AR	0006955	biological_process	immune response
AR	0016020	cellular_component	membrane
As	0005164	molecular_function	tumor necrosis factor receptor binding
As	0006955	biological_process	immune response
As	0016020	cellular_component	membrane
AS	0005164	molecular_function	tumor necrosis factor receptor binding
AS	0006955	biological_process	immune response
AS	0016020	cellular_component	membrane
At	0005164	molecular_function	tumor necrosis factor receptor binding
At	0006955	biological_process	immune response
At	0016020	cellular_component	membrane
AT	0005164	molecular_function	tumor necrosis factor receptor binding
AT	0006955	biological_process	immune response
AT	0016020	cellular_component	membrane
Au	0005164	molecular_function	tumor necrosis factor receptor binding
Au	0006955	biological_process	immune response
Au	0016020	cellular_component	membrane
AU	0005164	molecular_function	tumor necrosis factor receptor binding
AU	0006955	biological_process	immune response
AU	0016020	cellular_component	membrane
Av	0005164	molecular_function	tumor necrosis factor receptor binding
Av	0006955	biological_process	immune response
Av	0016020	cellular_component	membrane
AV	0005164	molecular_function	tumor necrosis factor receptor binding
AV	0006955	biological_process	immune response
AV	0016020	cellular_component	membrane
Aw	0005164	molecular_function	tumor necrosis factor receptor binding
Aw	0006955	biological_process	immune response
Aw	0016020	cellular_component	membrane
AW	0005164	molecular_function	tumor necrosis factor receptor binding
AW	0006955	biological_process	immune response
AW	0016020	cellular_component	membrane
Ax	0005164	molecular_function	tumor necrosis factor receptor binding
Ax	0006955	biological_process	immune response
Ax	0016020	cellular_component	membrane
AX	0005164	molecular_function	tumor necrosis factor receptor binding
AX	0006955	biological_process	immune response
AX	0016020	cellular_component	membrane
AY	0005164	molecular_function	tumor necrosis factor receptor binding
AY	0006955	biological_process	immune response
AY	0016020	cellular_component	membrane
AZ	0005164	molecular_function	tumor necrosis factor receptor binding
AZ	0006955	biological_process	immune response
AZ	0016020	cellular_component	membrane
B0	0033209	biological_process	tumor necrosis factor-mediated signaling pathway
B0	0038023	molecular_function	signaling receptor activity
B1	0033209	biological_process	tumor necrosis factor-mediated signaling pathway
B1	0038023	molecular_function	signaling receptor activity
B2	0033209	biological_process	tumor necrosis factor-mediated signaling pathway
B2	0038023	molecular_function	signaling receptor activity
B3	0033209	biological_process	tumor necrosis factor-mediated signaling pathway
B3	0038023	molecular_function	signaling receptor activity
B4	0033209	biological_process	tumor necrosis factor-mediated signaling pathway
B4	0038023	molecular_function	signaling receptor activity
B5	0033209	biological_process	tumor necrosis factor-mediated signaling pathway
B5	0038023	molecular_function	signaling receptor activity
B6	0033209	biological_process	tumor necrosis factor-mediated signaling pathway
B6	0038023	molecular_function	signaling receptor activity
B7	0033209	biological_process	tumor necrosis factor-mediated signaling pathway
B7	0038023	molecular_function	signaling receptor activity
B8	0033209	biological_process	tumor necrosis factor-mediated signaling pathway
B8	0038023	molecular_function	signaling receptor activity
B9	0033209	biological_process	tumor necrosis factor-mediated signaling pathway
B9	0038023	molecular_function	signaling receptor activity
Ba	0033209	biological_process	tumor necrosis factor-mediated signaling pathway
Ba	0038023	molecular_function	signaling receptor activity
BA	0033209	biological_process	tumor necrosis factor-mediated signaling pathway
BA	0038023	molecular_function	signaling receptor activity
Bb	0033209	biological_process	tumor necrosis factor-mediated signaling pathway
Bb	0038023	molecular_function	signaling receptor activity
BB	0033209	biological_process	tumor necrosis factor-mediated signaling pathway
BB	0038023	molecular_function	signaling receptor activity
Bc	0033209	biological_process	tumor necrosis factor-mediated signaling pathway
Bc	0038023	molecular_function	signaling receptor activity
BC	0033209	biological_process	tumor necrosis factor-mediated signaling pathway
BC	0038023	molecular_function	signaling receptor activity
Bd	0033209	biological_process	tumor necrosis factor-mediated signaling pathway
Bd	0038023	molecular_function	signaling receptor activity
BD	0033209	biological_process	tumor necrosis factor-mediated signaling pathway
BD	0038023	molecular_function	signaling receptor activity
Be	0033209	biological_process	tumor necrosis factor-mediated signaling pathway
Be	0038023	molecular_function	signaling receptor activity
BE	0033209	biological_process	tumor necrosis factor-mediated signaling pathway
BE	0038023	molecular_function	signaling receptor activity
Bf	0033209	biological_process	tumor necrosis factor-mediated signaling pathway
Bf	0038023	molecular_function	signaling receptor activity
BF	0033209	biological_process	tumor necrosis factor-mediated signaling pathway
BF	0038023	molecular_function	signaling receptor activity
Bg	0033209	biological_process	tumor necrosis factor-mediated signaling pathway
Bg	0038023	molecular_function	signaling receptor activity
BG	0033209	biological_process	tumor necrosis factor-mediated signaling pathway
BG	0038023	molecular_function	signaling receptor activity
Bh	0033209	biological_process	tumor necrosis factor-mediated signaling pathway
Bh	0038023	molecular_function	signaling receptor activity
BH	0033209	biological_process	tumor necrosis factor-mediated signaling pathway
BH	0038023	molecular_function	signaling receptor activity
Bi	0033209	biological_process	tumor necrosis factor-mediated signaling pathway
Bi	0038023	molecular_function	signaling receptor activity
BI	0033209	biological_process	tumor necrosis factor-mediated signaling pathway
BI	0038023	molecular_function	signaling receptor activity
Bj	0033209	biological_process	tumor necrosis factor-mediated signaling pathway
Bj	0038023	molecular_function	signaling receptor activity
BJ	0033209	biological_process	tumor necrosis factor-mediated signaling pathway
BJ	0038023	molecular_function	signaling receptor activity
Bk	0033209	biological_process	tumor necrosis factor-mediated signaling pathway
Bk	0038023	molecular_function	signaling receptor activity
BK	0033209	biological_process	tumor necrosis factor-mediated signaling pathway
BK	0038023	molecular_function	signaling receptor activity
Bl	0033209	biological_process	tumor necrosis factor-mediated signaling pathway
Bl	0038023	molecular_function	signaling receptor activity
BL	0033209	biological_process	tumor necrosis factor-mediated signaling pathway
BL	0038023	molecular_function	signaling receptor activity
Bm	0033209	biological_process	tumor necrosis factor-mediated signaling pathway
Bm	0038023	molecular_function	signaling receptor activity
BM	0033209	biological_process	tumor necrosis factor-mediated signaling pathway
BM	0038023	molecular_function	signaling receptor activity
Bn	0033209	biological_process	tumor necrosis factor-mediated signaling pathway
Bn	0038023	molecular_function	signaling receptor activity
BN	0033209	biological_process	tumor necrosis factor-mediated signaling pathway
BN	0038023	molecular_function	signaling receptor activity
Bo	0033209	biological_process	tumor necrosis factor-mediated signaling pathway
Bo	0038023	molecular_function	signaling receptor activity
BO	0033209	biological_process	tumor necrosis factor-mediated signaling pathway
BO	0038023	molecular_function	signaling receptor activity
Bp	0033209	biological_process	tumor necrosis factor-mediated signaling pathway
Bp	0038023	molecular_function	signaling receptor activity
BP	0033209	biological_process	tumor necrosis factor-mediated signaling pathway
BP	0038023	molecular_function	signaling receptor activity
Bq	0033209	biological_process	tumor necrosis factor-mediated signaling pathway
Bq	0038023	molecular_function	signaling receptor activity
BQ	0033209	biological_process	tumor necrosis factor-mediated signaling pathway
BQ	0038023	molecular_function	signaling receptor activity
Br	0033209	biological_process	tumor necrosis factor-mediated signaling pathway
Br	0038023	molecular_function	signaling receptor activity
BR	0033209	biological_process	tumor necrosis factor-mediated signaling pathway
BR	0038023	molecular_function	signaling receptor activity
Bs	0033209	biological_process	tumor necrosis factor-mediated signaling pathway
Bs	0038023	molecular_function	signaling receptor activity
BS	0033209	biological_process	tumor necrosis factor-mediated signaling pathway
BS	0038023	molecular_function	signaling receptor activity
Bt	0033209	biological_process	tumor necrosis factor-mediated signaling pathway
Bt	0038023	molecular_function	signaling receptor activity
BT	0033209	biological_process	tumor necrosis factor-mediated signaling pathway
BT	0038023	molecular_function	signaling receptor activity
Bu	0033209	biological_process	tumor necrosis factor-mediated signaling pathway
Bu	0038023	molecular_function	signaling receptor activity
BU	0033209	biological_process	tumor necrosis factor-mediated signaling pathway
BU	0038023	molecular_function	signaling receptor activity
Bv	0033209	biological_process	tumor necrosis factor-mediated signaling pathway
Bv	0038023	molecular_function	signaling receptor activity
BV	0033209	biological_process	tumor necrosis factor-mediated signaling pathway
BV	0038023	molecular_function	signaling receptor activity
Bw	0033209	biological_process	tumor necrosis factor-mediated signaling pathway
Bw	0038023	molecular_function	signaling receptor activity
BW	0033209	biological_process	tumor necrosis factor-mediated signaling pathway
BW	0038023	molecular_function	signaling receptor activity
Bx	0033209	biological_process	tumor necrosis factor-mediated signaling pathway
Bx	0038023	molecular_function	signaling receptor activity
BX	0033209	biological_process	tumor necrosis factor-mediated signaling pathway
BX	0038023	molecular_function	signaling receptor activity
BY	0033209	biological_process	tumor necrosis factor-mediated signaling pathway
BY	0038023	molecular_function	signaling receptor activity
BZ	0033209	biological_process	tumor necrosis factor-mediated signaling pathway
BZ	0038023	molecular_function	signaling receptor activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue MG AA 1001

Chain	Residue
AA	GLN234
AA	MG1002
AG	GLN234
AM	GLN234

site_id	AC2
Number of Residues	1
Details	binding site for residue MG AA 1002

Chain	Residue
AA	MG1001

site_id	AC3
Number of Residues	4
Details	binding site for residue MG AB 301

Chain	Residue
AB	GLN234
AH	GLN234
AN	GLN234
AN	MG301

site_id	AC4
Number of Residues	4
Details	binding site for residue MG AC 301

Chain	Residue
AC	GLN234
AI	GLN234
AO	GLN234
AO	MG301

site_id	AC5
Number of Residues	4
Details	binding site for residue MG AD 301

Chain	Residue
AD	GLN234
AJ	GLN234
AJ	MG301
AP	GLN234

site_id	AC6
Number of Residues	4
Details	binding site for residue MG AF 301

Chain	Residue
AF	GLN234
AL	GLN234
AR	GLN234
AR	MG301

site_id	AC7
Number of Residues	1
Details	binding site for residue MG AJ 301

Chain	Residue
AD	MG301

site_id	AC8
Number of Residues	1
Details	binding site for residue MG AN 301

Chain	Residue
AB	MG301

site_id	AC9
Number of Residues	1
Details	binding site for residue MG AO 301

Chain	Residue
AC	MG301

site_id	AD1
Number of Residues	4
Details	binding site for residue MG AQ 301

Chain	Residue
AE	GLN234
AK	GLN234
AQ	GLN234
AQ	MG302

site_id	AD2
Number of Residues	1
Details	binding site for residue MG AQ 302

Chain	Residue
AQ	MG301

site_id	AD3
Number of Residues	1
Details	binding site for residue MG AR 301

Chain	Residue
AF	MG301

site_id	AD4
Number of Residues	4
Details	binding site for residue MG A1 301

Chain	Residue
A1	GLN234
A7	GLN234
A7	MG301
AV	GLN234

site_id	AD5
Number of Residues	4
Details	binding site for residue MG A4 301

Chain	Residue
A4	GLN234
A4	MG302
AS	GLN234
AY	GLN234

site_id	AD6
Number of Residues	1
Details	binding site for residue MG A4 302

Chain	Residue
A4	MG301

site_id	AD7
Number of Residues	4
Details	binding site for residue MG A5 301

Chain	Residue
A5	GLN234
A5	MG302
AT	GLN234
AZ	GLN234

site_id	AD8
Number of Residues	1
Details	binding site for residue MG A5 302

Chain	Residue
A5	MG301

site_id	AD9
Number of Residues	4
Details	binding site for residue MG A6 301

Chain	Residue
A0	GLN234
A6	GLN234
A6	MG302
AU	GLN234

site_id	AE1
Number of Residues	1
Details	binding site for residue MG A6 302

Chain	Residue
A6	MG301

site_id	AE2
Number of Residues	1
Details	binding site for residue MG A7 301

Chain	Residue
A1	MG301

site_id	AE3
Number of Residues	4
Details	binding site for residue MG A8 301

Chain	Residue
A2	GLN234
A8	GLN234
A8	MG302
AW	GLN234

site_id	AE4
Number of Residues	1
Details	binding site for residue MG A8 302

Chain	Residue
A8	MG301

site_id	AE5
Number of Residues	4
Details	binding site for residue MG A9 301

Chain	Residue
A3	GLN234
A9	GLN234
A9	MG302
AX	GLN234

site_id	AE6
Number of Residues	2
Details	binding site for residue MG A9 302

Chain	Residue
A9	ASN235
A9	MG301

site_id	AE7
Number of Residues	4
Details	binding site for residue MG Aa 301

Chain	Residue
Aa	GLN234
Ag	GLN234
Am	GLN234
Am	MG301

site_id	AE8
Number of Residues	4
Details	binding site for residue MG Ac 301

Chain	Residue
Ac	GLN234
Ac	MG302
Ai	GLN234
Ao	GLN234

site_id	AE9
Number of Residues	1
Details	binding site for residue MG Ac 302

Chain	Residue
Ac	MG301

site_id	AF1
Number of Residues	4
Details	binding site for residue MG Ad 301

Chain	Residue
Ad	GLN234
Aj	GLN234
Ap	GLN234
Ap	MG301

site_id	AF2
Number of Residues	4
Details	binding site for residue MG Af 301

Chain	Residue
Af	GLN234
Al	GLN234
Ar	GLN234
Ar	MG301

site_id	AF3
Number of Residues	4
Details	binding site for residue MG Ah 301

Chain	Residue
Ab	GLN234
Ah	GLN234
An	GLN234
An	MG301

site_id	AF4
Number of Residues	4
Details	binding site for residue MG Ak 301

Chain	Residue
Ae	GLN234
Ak	GLN234
Aq	GLN234
Aq	MG301

site_id	AF5
Number of Residues	1
Details	binding site for residue MG Am 301

Chain	Residue
Aa	MG301

site_id	AF6
Number of Residues	2
Details	binding site for residue MG An 301

Chain	Residue
Ah	MG301
An	ASN235

site_id	AF7
Number of Residues	1
Details	binding site for residue MG Ap 301

Chain	Residue
Ad	MG301

site_id	AF8
Number of Residues	1
Details	binding site for residue MG Aq 301

Chain	Residue
Ak	MG301

site_id	AF9
Number of Residues	2
Details	binding site for residue MG Ar 301

Chain	Residue
Af	MG301
Ar	ASN235

site_id	AG1
Number of Residues	4
Details	binding site for residue MG As 301

Chain	Residue
As	GLN234
Au	GLN234
Av	GLN234
Av	MG301

site_id	AG2
Number of Residues	1
Details	binding site for residue MG Av 301

Chain	Residue
As	MG301

site_id	AG3
Number of Residues	4
Details	binding site for residue MG Aw 301

Chain	Residue
Aw	GLN234
Aw	MG302
Ax	GLN234
At	GLN234

site_id	AG4
Number of Residues	1
Details	binding site for residue MG Aw 302

Chain	Residue
Aw	MG301

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8340
Details	Domain: {"description":"THD","evidences":[{"source":"PROSITE-ProRule","id":"PRU01387","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	60
Details	Glycosylation: {"description":"N-linked (GlcNAc...) (high mannose) asparagine"}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	1020
Details	Repeat: {"description":"TNFR-Cys; truncated"}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	300
Details	Region: {"description":"Essential for TNFSF13B/TALL1/BAFF/BLyS binding"}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)