4V0O
Crystal structure of BBS1N in complex with ARL6DN, soaked with lead
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0003924 | molecular_function | GTPase activity |
| A | 0005525 | molecular_function | GTP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005856 | cellular_component | cytoskeleton |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0005930 | cellular_component | axoneme |
| A | 0006886 | biological_process | intracellular protein transport |
| A | 0016020 | cellular_component | membrane |
| A | 0016192 | biological_process | vesicle-mediated transport |
| A | 0030030 | biological_process | cell projection organization |
| A | 0042995 | cellular_component | cell projection |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0060170 | cellular_component | ciliary membrane |
| A | 0060271 | biological_process | cilium assembly |
| A | 0061512 | biological_process | protein localization to cilium |
| B | 0034464 | cellular_component | BBSome |
| B | 1905515 | biological_process | non-motile cilium assembly |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0003924 | molecular_function | GTPase activity |
| C | 0005525 | molecular_function | GTP binding |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0005856 | cellular_component | cytoskeleton |
| C | 0005886 | cellular_component | plasma membrane |
| C | 0005930 | cellular_component | axoneme |
| C | 0006886 | biological_process | intracellular protein transport |
| C | 0016020 | cellular_component | membrane |
| C | 0016192 | biological_process | vesicle-mediated transport |
| C | 0030030 | biological_process | cell projection organization |
| C | 0042995 | cellular_component | cell projection |
| C | 0046872 | molecular_function | metal ion binding |
| C | 0060170 | cellular_component | ciliary membrane |
| C | 0060271 | biological_process | cilium assembly |
| C | 0061512 | biological_process | protein localization to cilium |
| D | 0034464 | cellular_component | BBSome |
| D | 1905515 | biological_process | non-motile cilium assembly |
| E | 0000166 | molecular_function | nucleotide binding |
| E | 0003924 | molecular_function | GTPase activity |
| E | 0005525 | molecular_function | GTP binding |
| E | 0005737 | cellular_component | cytoplasm |
| E | 0005856 | cellular_component | cytoskeleton |
| E | 0005886 | cellular_component | plasma membrane |
| E | 0005930 | cellular_component | axoneme |
| E | 0006886 | biological_process | intracellular protein transport |
| E | 0016020 | cellular_component | membrane |
| E | 0016192 | biological_process | vesicle-mediated transport |
| E | 0030030 | biological_process | cell projection organization |
| E | 0042995 | cellular_component | cell projection |
| E | 0046872 | molecular_function | metal ion binding |
| E | 0060170 | cellular_component | ciliary membrane |
| E | 0060271 | biological_process | cilium assembly |
| E | 0061512 | biological_process | protein localization to cilium |
| F | 0034464 | cellular_component | BBSome |
| F | 1905515 | biological_process | non-motile cilium assembly |
| G | 0000166 | molecular_function | nucleotide binding |
| G | 0003924 | molecular_function | GTPase activity |
| G | 0005525 | molecular_function | GTP binding |
| G | 0005737 | cellular_component | cytoplasm |
| G | 0005856 | cellular_component | cytoskeleton |
| G | 0005886 | cellular_component | plasma membrane |
| G | 0005930 | cellular_component | axoneme |
| G | 0006886 | biological_process | intracellular protein transport |
| G | 0016020 | cellular_component | membrane |
| G | 0016192 | biological_process | vesicle-mediated transport |
| G | 0030030 | biological_process | cell projection organization |
| G | 0042995 | cellular_component | cell projection |
| G | 0046872 | molecular_function | metal ion binding |
| G | 0060170 | cellular_component | ciliary membrane |
| G | 0060271 | biological_process | cilium assembly |
| G | 0061512 | biological_process | protein localization to cilium |
| H | 0034464 | cellular_component | BBSome |
| H | 1905515 | biological_process | non-motile cilium assembly |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE GTP A 600 |
| Chain | Residue |
| A | ASP26 |
| A | GLY72 |
| A | ASN128 |
| A | LYS129 |
| A | ASP131 |
| A | ASN161 |
| A | GLY162 |
| A | LEU163 |
| A | MG601 |
| A | ASN27 |
| A | SER28 |
| A | GLY29 |
| A | LYS30 |
| A | THR31 |
| A | THR32 |
| A | THR50 |
| A | SER71 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG A 601 |
| Chain | Residue |
| A | LYS30 |
| A | THR31 |
| A | THR50 |
| A | GTP600 |
| site_id | AC3 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE GTP C 600 |
| Chain | Residue |
| C | ASN27 |
| C | SER28 |
| C | GLY29 |
| C | LYS30 |
| C | THR31 |
| C | THR32 |
| C | THR50 |
| C | SER71 |
| C | GLY72 |
| C | ASN128 |
| C | LYS129 |
| C | ASP131 |
| C | LEU132 |
| C | ASN161 |
| C | GLY162 |
| C | LEU163 |
| C | MG601 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG C 601 |
| Chain | Residue |
| C | THR31 |
| C | THR50 |
| C | ASP69 |
| C | MET70 |
| C | GTP600 |
| site_id | AC5 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE GTP E 600 |
| Chain | Residue |
| E | ASN27 |
| E | SER28 |
| E | GLY29 |
| E | LYS30 |
| E | THR31 |
| E | THR32 |
| E | THR50 |
| E | SER71 |
| E | GLY72 |
| E | ASN128 |
| E | LYS129 |
| E | ASP131 |
| E | LEU132 |
| E | ASN161 |
| E | GLY162 |
| E | LEU163 |
| E | MG601 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG E 601 |
| Chain | Residue |
| E | LYS30 |
| E | THR31 |
| E | THR50 |
| E | ASP69 |
| E | MET70 |
| E | GTP600 |
| site_id | AC7 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE GTP G 600 |
| Chain | Residue |
| G | ASN27 |
| G | SER28 |
| G | GLY29 |
| G | LYS30 |
| G | THR31 |
| G | THR32 |
| G | THR50 |
| G | MET70 |
| G | SER71 |
| G | GLY72 |
| G | ASN128 |
| G | LYS129 |
| G | ASP131 |
| G | ASN161 |
| G | GLY162 |
| G | MG601 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE MG G 601 |
| Chain | Residue |
| G | THR31 |
| G | THR50 |
| G | GTP600 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PB H 1426 |
| Chain | Residue |
| H | CYS57 |
| H | ALA74 |
| H | PRO98 |
| site_id | BC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PB B 1426 |
| Chain | Residue |
| B | CYS57 |
| B | ALA74 |
| B | PRO98 |
| site_id | BC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PB F 1426 |
| Chain | Residue |
| F | CYS57 |
| F | ALA74 |
| F | PRO98 |
| site_id | BC3 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE PB A 1182 |
| Chain | Residue |
| A | GLU57 |
| site_id | BC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PB H 1427 |
| Chain | Residue |
| H | GLU304 |
| H | CYS321 |
| H | VAL325 |
| H | HIS327 |
| site_id | BC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PB B 1427 |
| Chain | Residue |
| B | HIS59 |
| B | ILE101 |
| B | CYS102 |
| site_id | BC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE PB H 1428 |
| Chain | Residue |
| H | ILE101 |
| H | CYS102 |
| site_id | BC7 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE PB H 1429 |
| Chain | Residue |
| H | CYS61 |
| H | SER103 |
| site_id | BC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PB B 1428 |
| Chain | Residue |
| B | GLU304 |
| B | CYS321 |
| B | VAL325 |
| B | HIS327 |
| site_id | BC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PB F 1427 |
| Chain | Residue |
| F | GLU304 |
| F | CYS321 |
| F | VAL325 |
| F | HIS327 |
| site_id | CC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PB D 1426 |
| Chain | Residue |
| D | GLU304 |
| D | CYS321 |
| D | ASN323 |
| D | VAL325 |
| D | HIS327 |
| site_id | CC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PB D 1427 |
| Chain | Residue |
| D | CYS57 |
| D | ALA74 |
| D | PRO98 |
| site_id | CC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE PB B 1429 |
| Chain | Residue |
| B | CYS61 |
| B | SER103 |
| site_id | CC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PB F 1428 |
| Chain | Residue |
| F | HIS59 |
| F | ILE101 |
| F | CYS102 |
| site_id | CC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE PB D 1428 |
| Chain | Residue |
| D | ILE101 |
| D | CYS102 |
| site_id | CC6 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE PB E 1181 |
| Chain | Residue |
| E | ASP173 |
| site_id | CC7 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE PB A 1181 |
| Chain | Residue |
| A | ASP173 |
| site_id | CC8 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE PB G 1181 |
| Chain | Residue |
| G | ASP173 |
