4V0H
Human metallo beta lactamase domain containing protein 1 (hMBLAC1)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004521 | molecular_function | RNA endonuclease activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0008334 | biological_process | histone mRNA metabolic process |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0031124 | biological_process | mRNA 3'-end processing |
| A | 0046872 | molecular_function | metal ion binding |
| A | 1900087 | biological_process | positive regulation of G1/S transition of mitotic cell cycle |
| B | 0004521 | molecular_function | RNA endonuclease activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005634 | cellular_component | nucleus |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0008334 | biological_process | histone mRNA metabolic process |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0031124 | biological_process | mRNA 3'-end processing |
| B | 0046872 | molecular_function | metal ion binding |
| B | 1900087 | biological_process | positive regulation of G1/S transition of mitotic cell cycle |
| C | 0004521 | molecular_function | RNA endonuclease activity |
| C | 0005515 | molecular_function | protein binding |
| C | 0005634 | cellular_component | nucleus |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0005829 | cellular_component | cytosol |
| C | 0008334 | biological_process | histone mRNA metabolic process |
| C | 0016787 | molecular_function | hydrolase activity |
| C | 0031124 | biological_process | mRNA 3'-end processing |
| C | 0046872 | molecular_function | metal ion binding |
| C | 1900087 | biological_process | positive regulation of G1/S transition of mitotic cell cycle |
| D | 0004521 | molecular_function | RNA endonuclease activity |
| D | 0005515 | molecular_function | protein binding |
| D | 0005634 | cellular_component | nucleus |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0005829 | cellular_component | cytosol |
| D | 0008334 | biological_process | histone mRNA metabolic process |
| D | 0016787 | molecular_function | hydrolase activity |
| D | 0031124 | biological_process | mRNA 3'-end processing |
| D | 0046872 | molecular_function | metal ion binding |
| D | 1900087 | biological_process | positive regulation of G1/S transition of mitotic cell cycle |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE FE A 1242 |
| Chain | Residue |
| A | HIS117 |
| A | HIS119 |
| A | HIS172 |
| A | ASP195 |
| A | FE1243 |
| A | HOH2077 |
| A | HOH2078 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE FE B 1242 |
| Chain | Residue |
| B | HIS172 |
| B | ASP195 |
| B | FE1243 |
| B | HOH2083 |
| B | HOH2086 |
| B | HIS117 |
| B | HIS119 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE FE C 1242 |
| Chain | Residue |
| C | HIS117 |
| C | HIS119 |
| C | HIS172 |
| C | ASP195 |
| C | FE1243 |
| C | HOH2066 |
| C | HOH2067 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE FE D 1243 |
| Chain | Residue |
| D | HIS117 |
| D | HIS119 |
| D | HIS172 |
| D | ASP195 |
| D | FE1244 |
| D | HOH2066 |
| D | HOH2068 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE FE A 1243 |
| Chain | Residue |
| A | ASP121 |
| A | HIS122 |
| A | ASP195 |
| A | HIS234 |
| A | FE1242 |
| A | HOH2077 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE FE B 1243 |
| Chain | Residue |
| B | ASP121 |
| B | HIS122 |
| B | ASP195 |
| B | HIS234 |
| B | FE1242 |
| B | GOL1244 |
| B | HOH2083 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE FE C 1243 |
| Chain | Residue |
| C | ASP121 |
| C | HIS122 |
| C | ASP195 |
| C | HIS234 |
| C | FE1242 |
| C | GOL1244 |
| C | HOH2066 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE FE D 1244 |
| Chain | Residue |
| D | ASP121 |
| D | HIS122 |
| D | ASP195 |
| D | HIS234 |
| D | FE1243 |
| D | HOH2066 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL D 1245 |
| Chain | Residue |
| C | ASP139 |
| D | ALA43 |
| D | ASP121 |
| D | HOH2066 |
| D | HOH2068 |
| site_id | BC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL B 1244 |
| Chain | Residue |
| A | ASP139 |
| B | HIS119 |
| B | ASP121 |
| B | FE1243 |
| B | HOH2086 |
| site_id | BC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL C 1244 |
| Chain | Residue |
| C | ASP121 |
| C | FE1243 |
| C | HOH2066 |
| C | HOH2067 |
| D | ASP139 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 28 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"30507380","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"4V0H","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
