Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004672 | molecular_function | protein kinase activity |
| A | 0004713 | molecular_function | protein tyrosine kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006468 | biological_process | protein phosphorylation |
| B | 0004672 | molecular_function | protein kinase activity |
| B | 0004713 | molecular_function | protein tyrosine kinase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0006468 | biological_process | protein phosphorylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE G9B A 2099 |
| Chain | Residue |
| A | LEU828 |
| A | ASP912 |
| A | ARG953 |
| A | ASP967 |
| A | ALA853 |
| A | MET902 |
| A | GLU903 |
| A | TYR904 |
| A | LEU905 |
| A | PRO906 |
| A | GLY908 |
| A | CYS909 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE G9B B 2099 |
| Chain | Residue |
| B | ALA853 |
| B | MET902 |
| B | GLU903 |
| B | TYR904 |
| B | LEU905 |
| B | PRO906 |
| B | GLY908 |
| B | CYS909 |
| B | ASP912 |
| B | ASP967 |
| site_id | AC3 |
| Number of Residues | 10 |
| Details | Binding site for residues PTR A 980 and PTR A 981 |
| Chain | Residue |
| A | ARG870 |
| A | LYS972 |
| A | LEU973 |
| A | PRO975 |
| A | LYS978 |
| A | ASP979 |
| A | VAL982 |
| A | VAL983 |
| A | ILE1003 |
| A | PHE1004 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | Binding site for residues PTR B 980 and PTR B 981 |
| Chain | Residue |
| B | LYS972 |
| B | LEU973 |
| B | PRO975 |
| B | LYS978 |
| B | ASP979 |
| B | VAL982 |
| B | ILE1003 |
| B | PHE1004 |
Functional Information from PROSITE/UniProt
| site_id | PS00107 |
| Number of Residues | 28 |
| Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGKGNFGSVElCrydplgdntgal......VAVK |
| Chain | Residue | Details |
| A | LEU828-LYS855 | |
| B | LEU828-LYS855 | |
| site_id | PS00109 |
| Number of Residues | 13 |
| Details | PROTEIN_KINASE_TYR Tyrosine protein kinases specific active-site signature. CVHrDLAARNILV |
| Chain | Residue | Details |
| A | CYS945-VAL957 | |
| B | CYS945-VAL957 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"},{"source":"PROSITE-ProRule","id":"PRU10028","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 18 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"18250158","evidenceCode":"ECO:0000269"}]} |
