4UYE
BROMODOMAIN OF HUMAN BRPF1 WITH N-1,3-dimethyl-2-oxo-6-(piperidin-1- yl)-2,3-dihydro-1H-1,3-benzodiazol-5-yl-2-methoxybenzamide
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 1738 |
| Chain | Residue |
| A | ASN698 |
| A | SER702 |
| A | HOH2079 |
| B | ARG722 |
| B | GLU723 |
| site_id | AC2 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE 9F9 A 1739 |
| Chain | Residue |
| A | VAL657 |
| A | PRO658 |
| A | GLU661 |
| A | ASN708 |
| A | PHE714 |
| A | GLN735 |
| A | HOH2048 |
| A | HOH2131 |
| A | ILE635 |
| A | ASN651 |
| A | ILE652 |
| A | GLU655 |
| site_id | AC3 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE 9F9 B 1738 |
| Chain | Residue |
| B | LYS639 |
| B | ASN651 |
| B | ILE652 |
| B | GLU655 |
| B | VAL657 |
| B | PRO658 |
| B | GLU661 |
| B | ASN708 |
| B | PHE714 |
| B | HOH2046 |
| B | HOH2107 |
Functional Information from PROSITE/UniProt
| site_id | PS00633 |
| Number of Residues | 58 |
| Details | BROMODOMAIN_1 Bromodomain signature. GniFsepvPlsevp..DYLdhIkkpMdfftMkqnleayr..Ylnfddfeedfnl.IvsNClkY |
| Chain | Residue | Details |
| A | GLY650-TYR707 |
