4UY5

Crystal structure of Histidine-specific methyltransferase EgtD from Mycobacterium smegmatis

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008168	molecular_function	methyltransferase activity
A	0008276	molecular_function	protein methyltransferase activity
A	0016740	molecular_function	transferase activity
A	0032259	biological_process	methylation
A	0052699	biological_process	ergothioneine biosynthetic process
A	0052704	biological_process	ergothioneine biosynthesis from histidine via gamma-glutamyl-hercynylcysteine sulfoxide
A	0052706	molecular_function	L-histidine N(alpha)-methyltransferase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE IMD A 1328

Chain	Residue
A	PHE47
A	TYR206
A	PHE216
A	GLU282
A	HOH2055

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site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ACT A 1329

Chain	Residue
A	HOH2040
A	TYR56
A	ASN166
A	TYR206
A	SER284

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	5
Details	Binding site: {"evidences":[{"source":"PubMed","id":"25251321","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25404173","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"4UY6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4UY7","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	3
Details	Binding site: {"evidences":[{"source":"PubMed","id":"25251321","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"25404173","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"25251321","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"25404173","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"4PIO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4PIP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4UY6","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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