4USW
Crystal structure of human soluble Adenylyl Cyclase with ATP
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NA A 1468 |
| Chain | Residue |
| A | ASP47 |
| A | ASP99 |
| A | ATP1471 |
| A | HOH2037 |
| A | HOH2073 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE ACT A 1469 |
| Chain | Residue |
| A | VAL335 |
| A | GOL1472 |
| A | HOH2069 |
| A | LYS95 |
| A | HIS164 |
| A | ASN333 |
| A | LYS334 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE ACT A 1470 |
| Chain | Residue |
| A | LYS95 |
| A | LEU166 |
| A | VAL167 |
| A | ARG176 |
| A | PHE336 |
| A | HOH2095 |
| A | HOH2201 |
| site_id | AC4 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE ATP A 1471 |
| Chain | Residue |
| A | ASP47 |
| A | ILE48 |
| A | SER49 |
| A | GLY50 |
| A | PHE51 |
| A | THR52 |
| A | ALA97 |
| A | GLY98 |
| A | ASP99 |
| A | LYS144 |
| A | PHE336 |
| A | PHE338 |
| A | LEU345 |
| A | THR405 |
| A | VAL406 |
| A | ASN412 |
| A | ARG416 |
| A | NA1468 |
| A | HOH2038 |
| A | HOH2040 |
| A | HOH2072 |
| A | HOH2073 |
| A | HOH2168 |
| site_id | AC5 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE GOL A 1472 |
| Chain | Residue |
| A | HIS19 |
| A | LYS95 |
| A | PHE165 |
| A | TYR268 |
| A | LYS334 |
| A | GLU403 |
| A | ACT1469 |
| A | HOH2009 |
| A | HOH2010 |
| A | HOH2069 |
| A | HOH2202 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00099 |
| Chain | Residue | Details |
| A | ASP47 | |
| A | ILE48 | |
| A | ASP99 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:24567411, ECO:0000269|PubMed:24616449, ECO:0007744|PDB:4CLL, ECO:0007744|PDB:4OYZ |
| Chain | Residue | Details |
| A | LYS95 | |
| A | VAL167 | |
| A | ARG176 | |
| A | MET337 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:25040695, ECO:0000305|PubMed:24567411, ECO:0000305|PubMed:24616449, ECO:0007744|PDB:4USW |
| Chain | Residue | Details |
| A | LYS144 | |
| A | VAL406 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000305|PubMed:24567411, ECO:0000305|PubMed:24616449, ECO:0000305|PubMed:25040695 |
| Chain | Residue | Details |
| A | ASN412 |
