Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 36 |
| Details | BINDING SITE FOR RESIDUE NAD A 1249 |
| Chain | Residue |
| A | GLY12 |
| A | ASP62 |
| A | THR63 |
| A | ASN89 |
| A | ALA90 |
| A | GLY91 |
| A | ILE113 |
| A | ILE140 |
| A | SER141 |
| A | TYR155 |
| A | LYS159 |
| A | GLY14 |
| A | PRO185 |
| A | ALA186 |
| A | ILE188 |
| A | THR190 |
| A | ACT1250 |
| A | HOH2020 |
| A | HOH2026 |
| A | HOH2092 |
| A | HOH2133 |
| A | HOH2155 |
| A | ASN15 |
| A | HOH2181 |
| A | HOH2201 |
| A | HOH2266 |
| A | HOH2267 |
| A | HOH2268 |
| A | HOH2269 |
| A | HOH2270 |
| A | GLY16 |
| A | ILE17 |
| A | ASP36 |
| A | ILE37 |
| A | TRP41 |
| A | ALA61 |
| site_id | AC2 |
| Number of Residues | 35 |
| Details | BINDING SITE FOR RESIDUE NAD B 1249 |
| Chain | Residue |
| B | GLY12 |
| B | GLY14 |
| B | ASN15 |
| B | GLY16 |
| B | ILE17 |
| B | ASP36 |
| B | ILE37 |
| B | TRP41 |
| B | ALA61 |
| B | ASP62 |
| B | THR63 |
| B | ASN89 |
| B | ALA90 |
| B | GLY91 |
| B | ILE113 |
| B | ILE140 |
| B | SER141 |
| B | TYR155 |
| B | LYS159 |
| B | PRO185 |
| B | ALA186 |
| B | PHE187 |
| B | ILE188 |
| B | THR190 |
| B | ACT1250 |
| B | HOH2018 |
| B | HOH2022 |
| B | HOH2086 |
| B | HOH2113 |
| B | HOH2133 |
| B | HOH2172 |
| B | HOH2206 |
| B | HOH2207 |
| B | HOH2208 |
| B | HOH2209 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ACT A 1250 |
| Chain | Residue |
| A | SER142 |
| A | TYR155 |
| A | NAD1249 |
| A | HOH2182 |
| A | HOH2266 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ACT B 1250 |
| Chain | Residue |
| B | SER142 |
| B | TYR155 |
| B | NAD1249 |
| B | HOH2206 |
| B | HOH2210 |
| site_id | AC5 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE 1PS B 1251 |
| Chain | Residue |
| A | GLY174 |
| A | SER175 |
| A | GLY177 |
| A | LEU198 |
| A | ARG202 |
| A | HOH2240 |
| B | LEU210 |
| B | ARG211 |
| B | ARG212 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE 1PS A 1251 |
| Chain | Residue |
| A | ILE92 |
| A | SER93 |
| A | GLY94 |
| A | ARG109 |
| A | HOH2271 |
| A | HOH2272 |
| site_id | AC7 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE 1PS A 1252 |
| Chain | Residue |
| A | GLN106 |
| A | HOH2139 |
| A | HOH2149 |
| B | THR103 |
| B | ASP104 |
| B | ALA105 |
| B | HOH2124 |
| A | GLU95 |
| A | GLU101 |
| A | THR103 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE BCT B 1252 |
| Chain | Residue |
| B | ILE92 |
| B | GLY94 |
| B | ARG109 |
| B | HOH2212 |
| B | HOH2213 |
| B | HOH2214 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE BCT B 1253 |
| Chain | Residue |
| B | ARG179 |
| B | SER228 |
| B | ASP229 |
| B | HOH2008 |
| B | HOH2146 |
| site_id | BC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG A 1257 |
| Chain | Residue |
| A | HOH2060 |
| A | HOH2061 |
| A | HOH2062 |
| A | HOH2069 |
| A | HOH2275 |
| A | HOH2276 |
| site_id | BC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ACT A 1253 |
| Chain | Residue |
| A | ARG179 |
| A | SER228 |
| A | ASP229 |
| A | HOH2012 |
| A | HOH2168 |
| site_id | BC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE MG B 1254 |
| Chain | Residue |
| B | ARG248 |
| B | ARG248 |
| B | HOH2200 |
| B | HOH2200 |
| B | HOH2201 |
| B | HOH2201 |
| B | HOH2205 |
| B | HOH2205 |
| site_id | BC4 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE MG A 1254 |
| Chain | Residue |
| A | ARG248 |
| A | ARG248 |
| A | HOH2259 |
| A | HOH2259 |
| A | HOH2261 |
| A | HOH2261 |
| A | HOH2265 |
| A | HOH2265 |
| site_id | BC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG A 1255 |
| Chain | Residue |
| A | GLU131 |
| A | HOH2112 |
| A | HOH2164 |
| A | HOH2165 |
| A | HOH2166 |
| A | HOH2273 |
| site_id | BC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG A 1256 |
| Chain | Residue |
| A | SER237 |
| A | TYR238 |
| A | HOH2245 |
| A | HOH2246 |
| A | HOH2248 |
| A | HOH2274 |
Functional Information from PROSITE/UniProt
| site_id | PS00061 |
| Number of Residues | 29 |
| Details | ADH_SHORT Short-chain dehydrogenases/reductases family signature. SiagqigiegItpYTAAKHGVvGLTkTVA |
| Chain | Residue | Details |
| A | SER142-ALA170 | |
