Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004497 | molecular_function | monooxygenase activity |
| A | 0005506 | molecular_function | iron ion binding |
| A | 0006629 | biological_process | lipid metabolic process |
| A | 0006694 | biological_process | steroid biosynthetic process |
| A | 0008202 | biological_process | steroid metabolic process |
| A | 0008398 | molecular_function | sterol 14-demethylase activity |
| A | 0016020 | cellular_component | membrane |
| A | 0016126 | biological_process | sterol biosynthetic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016705 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
| A | 0020037 | molecular_function | heme binding |
| A | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE HEM A 1450 |
| Chain | Residue |
| A | PHE90 |
| A | GLY414 |
| A | PHE415 |
| A | GLY416 |
| A | ALA417 |
| A | HIS420 |
| A | LYS421 |
| A | CYS422 |
| A | ILE423 |
| A | GLY424 |
| A | 25S1485 |
| A | TYR116 |
| A | LEU127 |
| A | ALA291 |
| A | THR295 |
| A | THR299 |
| A | PRO355 |
| A | VAL359 |
| A | ARG361 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE 25S A 1485 |
| Chain | Residue |
| A | PHE48 |
| A | MET106 |
| A | ALA291 |
| A | MET358 |
| A | MET360 |
| A | MET460 |
| A | VAL461 |
| A | HEM1450 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1478 |
| Chain | Residue |
| A | GLY111 |
| A | GLU112 |
| A | ARG230 |
| A | ARG233 |
| A | HIS279 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1479 |
| Chain | Residue |
| A | HIS306 |
| A | HIS309 |
| A | LYS311 |
| A | ASN312 |
| A | TRP400 |
| A | VAL452 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1480 |
| Chain | Residue |
| A | GLN140 |
| A | PRO144 |
| A | ASN331 |
| A | TYR332 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1481 |
| Chain | Residue |
| A | SER277 |
| A | SER277 |
| A | LEU278 |
| A | LEU278 |
| A | HOH2030 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1482 |
| Chain | Residue |
| A | ARG347 |
| A | PHE412 |
| A | GLN425 |
| A | HOH2054 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1483 |
| Chain | Residue |
| A | GLU406 |
| A | ASP409 |
| A | ALA417 |
| A | GLY418 |
| A | LYS421 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1484 |
| Chain | Residue |
| A | HIS84 |
| A | GLU85 |
| A | GLU85 |
| A | ARG88 |
| A | GLY370 |
Functional Information from PROSITE/UniProt
| site_id | PS00086 |
| Number of Residues | 10 |
| Details | CYTOCHROME_P450 Cytochrome P450 cysteine heme-iron ligand signature. FGaGVHKCIG |
| Chain | Residue | Details |
| A | PHE415-GLY424 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Binding site: {"description":"axial binding residue","evidences":[{"source":"UniProtKB","id":"P0A512","evidenceCode":"ECO:0000250"}]} |
