4UNN

Mtb TMK in complex with compound 8

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0000287	molecular_function	magnesium ion binding
A	0004798	molecular_function	dTMP kinase activity
A	0005524	molecular_function	ATP binding
A	0005525	molecular_function	GTP binding
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006227	biological_process	dUDP biosynthetic process
A	0006233	biological_process	dTDP biosynthetic process
A	0006235	biological_process	dTTP biosynthetic process
A	0009165	biological_process	nucleotide biosynthetic process
A	0016301	molecular_function	kinase activity
A	0016740	molecular_function	transferase activity
A	0042803	molecular_function	protein homodimerization activity
A	0046044	biological_process	TMP metabolic process
A	0046872	molecular_function	metal ion binding
B	0000166	molecular_function	nucleotide binding
B	0000287	molecular_function	magnesium ion binding
B	0004798	molecular_function	dTMP kinase activity
B	0005524	molecular_function	ATP binding
B	0005525	molecular_function	GTP binding
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006227	biological_process	dUDP biosynthetic process
B	0006233	biological_process	dTDP biosynthetic process
B	0006235	biological_process	dTTP biosynthetic process
B	0009165	biological_process	nucleotide biosynthetic process
B	0016301	molecular_function	kinase activity
B	0016740	molecular_function	transferase activity
B	0042803	molecular_function	protein homodimerization activity
B	0046044	biological_process	TMP metabolic process
B	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	13
Details	BINDING SITE FOR RESIDUE QZZ A 1210

Chain	Residue
A	ASP9
A	ASN100
A	TYR103
A	SER104
A	ARG107
A	PRO37
A	LEU52
A	VAL63
A	MET66
A	PHE70
A	ARG74
A	ARG95
A	SER99

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site_id	AC2
Number of Residues	11
Details	BINDING SITE FOR RESIDUE QZZ B 1210

Chain	Residue
B	ASP9
B	PRO37
B	LEU52
B	PHE70
B	ARG74
B	ARG95
B	SER99
B	ASN100
B	TYR103
B	SER104
B	ARG107

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Functional Information from PROSITE/UniProt

site_id	PS01331
Number of Residues	13
Details	THYMIDYLATE_KINASE Thymidylate kinase signature. ILDRYvaSNaAYS

Chain	Residue	Details
A	ILE92-SER104

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	28
Details	Binding site: {}

Chain

Residue

Details

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