4UNF
Crystal structure of Deinococcus radiodurans Endonuclease III-1
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000703 | molecular_function | oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0003906 | molecular_function | DNA-(apurinic or apyrimidinic site) endonuclease activity |
| A | 0004519 | molecular_function | endonuclease activity |
| A | 0006281 | biological_process | DNA repair |
| A | 0006284 | biological_process | base-excision repair |
| A | 0006285 | biological_process | base-excision repair, AP site formation |
| A | 0006289 | biological_process | nucleotide-excision repair |
| A | 0006974 | biological_process | DNA damage response |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0051536 | molecular_function | iron-sulfur cluster binding |
| A | 0051539 | molecular_function | 4 iron, 4 sulfur cluster binding |
| A | 0140097 | molecular_function | catalytic activity, acting on DNA |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SF4 A 1248 |
| Chain | Residue |
| A | CYS217 |
| A | CYS224 |
| A | CYS227 |
| A | CYS233 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG A 1249 |
| Chain | Residue |
| A | HOH2067 |
| A | ILE115 |
| A | LYS116 |
| A | ALA118 |
| A | GLY120 |
| A | GLY121 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG A 1250 |
| Chain | Residue |
| A | THR140 |
| A | LEU142 |
| A | VAL145 |
| A | HOH2074 |
| A | HOH2077 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ACT A 1251 |
| Chain | Residue |
| A | ASN15 |
| A | ARG18 |
| A | ARG232 |
| A | CYS233 |
| A | ASP234 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ACT A 1252 |
| Chain | Residue |
| A | HOH2092 |
| A | HOH2094 |
| A | HOH2126 |
Functional Information from PROSITE/UniProt
| site_id | PS00764 |
| Number of Residues | 17 |
| Details | ENDONUCLEASE_III_1 Endonuclease III iron-sulfur binding region signature. CtwtRPKCgkCilrerC |
| Chain | Residue | Details |
| A | CYS217-CYS233 |
