4UM4

STRUCTURE OF INORGANIC PYROPHOSPHATASE FROM ESCHERICHIA COLI IN COMPLEX WITH SULFATE

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000287	molecular_function	magnesium ion binding
A	0004427	molecular_function	inorganic diphosphate phosphatase activity
A	0005515	molecular_function	protein binding
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006796	biological_process	phosphate-containing compound metabolic process
A	0008270	molecular_function	zinc ion binding
A	0016020	cellular_component	membrane
A	0016787	molecular_function	hydrolase activity
A	0046872	molecular_function	metal ion binding
A	0050355	molecular_function	inorganic triphosphate phosphatase activity
B	0000287	molecular_function	magnesium ion binding
B	0004427	molecular_function	inorganic diphosphate phosphatase activity
B	0005515	molecular_function	protein binding
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006796	biological_process	phosphate-containing compound metabolic process
B	0008270	molecular_function	zinc ion binding
B	0016020	cellular_component	membrane
B	0016787	molecular_function	hydrolase activity
B	0046872	molecular_function	metal ion binding
B	0050355	molecular_function	inorganic triphosphate phosphatase activity
C	0000287	molecular_function	magnesium ion binding
C	0004427	molecular_function	inorganic diphosphate phosphatase activity
C	0005515	molecular_function	protein binding
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0006796	biological_process	phosphate-containing compound metabolic process
C	0008270	molecular_function	zinc ion binding
C	0016020	cellular_component	membrane
C	0016787	molecular_function	hydrolase activity
C	0046872	molecular_function	metal ion binding
C	0050355	molecular_function	inorganic triphosphate phosphatase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 C 1176

Chain	Residue
C	LYS29
C	TYR55
C	ASP70
C	ASP102
C	LYS104
C	TYR141

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site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 B 1176

Chain	Residue
B	ASP102
B	LYS104
B	LYS29
B	TYR55
B	ASP70

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site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 A 1176

Chain	Residue
A	LYS29
A	TYR51
A	TYR55
A	ASP102
A	LYS104
A	TYR141

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Functional Information from PROSITE/UniProt

site_id	PS00387
Number of Residues	7
Details	PPASE Inorganic pyrophosphatase signature. DGDPVDV

Chain	Residue	Details
A	ASP65-VAL71

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	21
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00209

Chain	Residue	Details
A	LYS29
B	TYR55
B	ASP65
B	ASP70
B	ASP102
B	TYR141
C	LYS29
C	ARG43
C	TYR55
C	ASP65
C	ASP70
A	ARG43
C	ASP102
C	TYR141
A	TYR55
A	ASP65
A	ASP70
A	ASP102
A	TYR141
B	LYS29
B	ARG43

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