4UIW
BROMODOMAIN OF HUMAN BRD9 WITH N-(1,1-dioxo-1-thian-4-yl)-5-ethyl-4- oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c-pyridine-2- carboximidamide
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE EDO A 1123 |
| Chain | Residue |
| A | GLN37 |
| A | ALA46 |
| A | PHE47 |
| A | GLY68 |
| A | PHE118 |
| A | HOH2037 |
| A | HOH2039 |
| A | HOH2136 |
| A | HOH2223 |
| site_id | AC2 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE H1B A 1124 |
| Chain | Residue |
| A | PHE44 |
| A | PHE45 |
| A | VAL49 |
| A | ILE53 |
| A | TYR99 |
| A | ASN100 |
| A | ARG101 |
| A | THR104 |
| A | TYR106 |
| A | LYS111 |
| A | HOH2112 |
| A | HOH2206 |
| A | HOH2224 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Region: {"description":"Histone H4K5ac H4K8ac and histone H4K5bu H4K8bu binding","evidences":[{"source":"PubMed","id":"26365797","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Site: {"description":"Histone H4K5ac H4K8ac and histone H4K5bu H4K8bu binding","evidences":[{"source":"PubMed","id":"26365797","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
