Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004517 | molecular_function | nitric-oxide synthase activity |
| A | 0006809 | biological_process | nitric oxide biosynthetic process |
| B | 0004517 | molecular_function | nitric-oxide synthase activity |
| B | 0006809 | biological_process | nitric oxide biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE HEM A 750 |
| Chain | Residue |
| A | TRP414 |
| A | TYR711 |
| A | H4B760 |
| A | EXI800 |
| A | HOH2169 |
| A | HOH2170 |
| A | HOH2171 |
| A | HOH2172 |
| A | CYS420 |
| A | PHE589 |
| A | SER590 |
| A | TRP592 |
| A | MET594 |
| A | GLU597 |
| A | TRP683 |
| A | PHE709 |
| site_id | AC2 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE H4B A 760 |
| Chain | Residue |
| A | SER339 |
| A | ARG601 |
| A | VAL682 |
| A | TRP683 |
| A | HEM750 |
| A | EXI800 |
| A | HOH2045 |
| A | HOH2131 |
| A | HOH2160 |
| B | TRP681 |
| B | PHE696 |
| B | HIS697 |
| B | GLN698 |
| B | GLU699 |
| site_id | AC3 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE EXI A 800 |
| Chain | Residue |
| A | GLN483 |
| A | ARG486 |
| A | TYR567 |
| A | PRO570 |
| A | TRP592 |
| A | TYR593 |
| A | GLU597 |
| A | ARG601 |
| A | ARG608 |
| A | HEM750 |
| A | H4B760 |
| A | HOH2128 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 900 |
| Chain | Residue |
| A | CYS331 |
| A | CYS336 |
| B | CYS331 |
| B | CYS336 |
| site_id | AC5 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE HEM B 750 |
| Chain | Residue |
| B | TRP414 |
| B | CYS420 |
| B | SER462 |
| B | PHE589 |
| B | SER590 |
| B | TRP592 |
| B | GLU597 |
| B | TRP683 |
| B | TYR711 |
| B | H4B760 |
| B | EXI800 |
| B | HOH2122 |
| B | HOH2123 |
| B | HOH2124 |
| site_id | AC6 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE H4B B 760 |
| Chain | Residue |
| A | TRP681 |
| A | PHE696 |
| A | HIS697 |
| A | GLN698 |
| A | GLU699 |
| A | HOH2163 |
| B | SER339 |
| B | MET341 |
| B | ARG601 |
| B | VAL682 |
| B | TRP683 |
| B | HEM750 |
| B | EXI800 |
| B | HOH2031 |
| B | HOH2099 |
| B | HOH2115 |
| site_id | AC7 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL B 780 |
| site_id | AC8 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE EXI B 800 |
| Chain | Residue |
| B | GLN483 |
| B | ARG486 |
| B | TYR567 |
| B | PRO570 |
| B | VAL572 |
| B | PHE589 |
| B | TRP592 |
| B | TYR593 |
| B | GLU597 |
| B | ARG608 |
| B | HEM750 |
| B | H4B760 |
Functional Information from PROSITE/UniProt
| site_id | PS60001 |
| Number of Residues | 8 |
| Details | NOS Nitric oxide synthase (NOS) signature. RCVGRIqW |
| Chain | Residue | Details |
| A | ARG419-TRP426 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 18 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"25286850","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4D1N","evidenceCode":"ECO:0007744"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Binding site: {"description":"axial binding residue","evidences":[{"source":"PubMed","id":"25286850","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4D1N","evidenceCode":"ECO:0007744"}]} |
