4UE3

The Mechanism of Hydrogen Activation by NiFe-hydrogenases and the Importance of the active site Arginine

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
LLL	0005515	molecular_function	protein binding
LLL	0005886	cellular_component	plasma membrane
LLL	0006113	biological_process	fermentation
LLL	0008901	molecular_function	ferredoxin hydrogenase activity
LLL	0009055	molecular_function	electron transfer activity
LLL	0009061	biological_process	anaerobic respiration
LLL	0009267	biological_process	cellular response to starvation
LLL	0016020	cellular_component	membrane
LLL	0016151	molecular_function	nickel cation binding
LLL	0016491	molecular_function	oxidoreductase activity
LLL	0019645	biological_process	anaerobic electron transport chain
LLL	0030288	cellular_component	outer membrane-bounded periplasmic space
LLL	0033748	molecular_function	hydrogenase (acceptor) activity
LLL	0044569	cellular_component	[Ni-Fe] hydrogenase complex
LLL	0046872	molecular_function	metal ion binding
LLL	0098567	cellular_component	periplasmic side of plasma membrane
LLL	1902421	biological_process	hydrogen metabolic process
MMM	0005515	molecular_function	protein binding
MMM	0005886	cellular_component	plasma membrane
MMM	0006113	biological_process	fermentation
MMM	0008901	molecular_function	ferredoxin hydrogenase activity
MMM	0009055	molecular_function	electron transfer activity
MMM	0009061	biological_process	anaerobic respiration
MMM	0009267	biological_process	cellular response to starvation
MMM	0016020	cellular_component	membrane
MMM	0016151	molecular_function	nickel cation binding
MMM	0016491	molecular_function	oxidoreductase activity
MMM	0019645	biological_process	anaerobic electron transport chain
MMM	0030288	cellular_component	outer membrane-bounded periplasmic space
MMM	0033748	molecular_function	hydrogenase (acceptor) activity
MMM	0044569	cellular_component	[Ni-Fe] hydrogenase complex
MMM	0046872	molecular_function	metal ion binding
MMM	0098567	cellular_component	periplasmic side of plasma membrane
MMM	1902421	biological_process	hydrogen metabolic process
SSS	0008901	molecular_function	ferredoxin hydrogenase activity
SSS	0009375	cellular_component	ferredoxin hydrogenase complex
SSS	0051536	molecular_function	iron-sulfur cluster binding
TTT	0008901	molecular_function	ferredoxin hydrogenase activity
TTT	0009375	cellular_component	ferredoxin hydrogenase complex
TTT	0051536	molecular_function	iron-sulfur cluster binding

Functional Information from PROSITE/UniProt

site_id	PS00507
Number of Residues	26
Details	NI_HGENASE_L_1 Nickel-dependent hydrogenases large subunit signature 1. RGLEiilqgrdprdawafvERiCGVC

Chain	Residue	Details
LLL	ARG54-CSO79

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site_id	PS00508
Number of Residues	10
Details	NI_HGENASE_L_2 Nickel-dependent hydrogenases large subunit signature 2. FDPCLACst.H

Chain	Residue	Details
LLL	PHE573-HIS582

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	BINDING: BINDING => ECO:0000255

Chain	Residue	Details
LLL	CYS76
SSS	CYS249
SSS	CYS252
TTT	CYS17
TTT	CYS20
TTT	CYS115
TTT	CYS149
TTT	HIS187
TTT	CYS190
TTT	CYS215
TTT	CYS221
LLL	CSO79
TTT	CYS230
TTT	CYS249
TTT	CYS252
LLL	CYS576
LLL	CYS579
MMM	CYS76
MMM	CSO79
MMM	CYS576
MMM	CYS579
SSS	CYS230

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