Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005515 | molecular_function | protein binding |
| A | 0015643 | molecular_function | toxic substance binding |
| A | 0030153 | biological_process | bacteriocin immunity |
| B | 0003723 | molecular_function | RNA binding |
| B | 0016788 | molecular_function | hydrolase activity, acting on ester bonds |
| B | 0043022 | molecular_function | ribosome binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CA A 1086 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CA B 1097 |
| Chain | Residue |
| B | ASP55 |
| B | HIS58 |
| B | GLU60 |
| B | GLU62 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA B 1098 |
| Chain | Residue |
| B | ARG40 |
| B | ARG42 |
| B | GLU53 |
| B | PRO29 |
| B | LYS30 |
| B | THR31 |
| site_id | AC4 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL A 1087 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 94 |
| Details | Region: {"description":"Cytotoxic RNase (C) domain","evidences":[{"source":"PubMed","id":"11741540","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 34 |
| Details | Region: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 21 |
| Details | Region: {"description":"Binding of immunity protein"} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton donor","evidences":[{"source":"PubMed","id":"11741540","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"20852642","evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PubMed","id":"11741540","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"20852642","evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | Active site: {"evidences":[{"source":"PubMed","id":"11741540","evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | Site: {"description":"Stabilizes positive charge on His-513","evidences":[{"source":"PubMed","id":"20852642","evidenceCode":"ECO:0000305"}]} |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 4 |
| Details | M-CSA 530 |
| Chain | Residue | Details |
| B | ASP55 | electrostatic stabiliser, increase acidity |
| B | HIS58 | promote heterolysis, proton acceptor, proton donor |
| B | GLU62 | increase nucleophilicity, promote heterolysis, proton acceptor, proton donor |
| B | ARG90 | electrostatic stabiliser |
