4UCU

Fragment bound to H.influenza NAD dependent DNA ligase

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003911	molecular_function	DNA ligase (NAD+) activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	8
Details	BINDING SITE FOR RESIDUE 8HC A 1319

Chain	Residue
A	LEU80
A	LEU82
A	GLU114
A	TYR226
A	LYS291
A	TRP310
A	HOH2059
A	HOH2120

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site_id	AC2
Number of Residues	10
Details	BINDING SITE FOR RESIDUE IWH A 1320

Chain	Residue
A	TYR22
A	HIS23
A	ASN27
A	VAL30
A	PRO31
A	ASP32
A	TYR35
A	HOH2021
A	HOH2029
A	TYR18

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Functional Information from PROSITE/UniProt

site_id	PS01055
Number of Residues	30
Details	DNA_LIGASE_N1 NAD-dependent DNA ligase signature 1. KLDGLAvsilYvnGeLtqaaTRGDGttGED

Chain	Residue	Details
A	LYS116-ASP145

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Active site: {"description":"N6-AMP-lysine intermediate","evidences":[{"source":"HAMAP-Rule","id":"MF_01588","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	10
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01588","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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