4UBE

CRYSTAL STRUCTURE OF M TUBERCULOSIS ADENOSINE KINASE COMPLEXED WITH 2-FLURO ADENOSINE

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004001	molecular_function	adenosine kinase activity
A	0005524	molecular_function	ATP binding
A	0006166	biological_process	purine ribonucleoside salvage
A	0016301	molecular_function	kinase activity
A	0016772	molecular_function	transferase activity, transferring phosphorus-containing groups
A	0044209	biological_process	AMP salvage

Functional Information from PDB Data

site_id	AC1
Number of Residues	16
Details	binding site for residue 2FA A 401

Chain	Residue
A	SER8
A	MET121
A	ALA146
A	ASN147
A	GLN172
A	GLN173
A	ASP257
A	HOH598
A	ASP12
A	SER36
A	GLY47
A	GLY48
A	VAL49
A	ASN52
A	PHE102
A	PHE116

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Functional Information from PROSITE/UniProt

site_id	PS00583
Number of Residues	25
Details	PFKB_KINASES_1 pfkB family of carbohydrate kinases signature 1. GGvAgNMAfaIgVLGgevalvgaaG

Chain	Residue	Details
A	GLY47-GLY71

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Proton acceptor => ECO:0000250|UniProtKB:P9WID5

Chain	Residue	Details
A	ASP257

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site_id	SWS_FT_FI2
Number of Residues	8
Details	BINDING: in other chain => ECO:0000305|Ref.3, ECO:0007744|PDB:4UBE

Chain	Residue	Details
A	SER8
A	ASP12
A	GLY48
A	ASN52
A	PHE102
A	PHE116
A	GLN172
A	ASP257

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site_id	SWS_FT_FI3
Number of Residues	1
Details	BINDING: BINDING => ECO:0000305|Ref.3, ECO:0007744|PDB:4UBE

Chain	Residue	Details
A	SER36

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site_id	SWS_FT_FI4
Number of Residues	3
Details	BINDING: BINDING => ECO:0000250|UniProtKB:P9WID5

Chain	Residue	Details
A	ASN195
A	THR223
A	GLY256

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