4UBE
CRYSTAL STRUCTURE OF M TUBERCULOSIS ADENOSINE KINASE COMPLEXED WITH 2-FLURO ADENOSINE
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004001 | molecular_function | adenosine kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006166 | biological_process | purine ribonucleoside salvage |
| A | 0016301 | molecular_function | kinase activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016772 | molecular_function | transferase activity, transferring phosphorus-containing groups |
| A | 0044209 | biological_process | AMP salvage |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 16 |
| Details | binding site for residue 2FA A 401 |
| Chain | Residue |
| A | SER8 |
| A | MET121 |
| A | ALA146 |
| A | ASN147 |
| A | GLN172 |
| A | GLN173 |
| A | ASP257 |
| A | HOH598 |
| A | ASP12 |
| A | SER36 |
| A | GLY47 |
| A | GLY48 |
| A | VAL49 |
| A | ASN52 |
| A | PHE102 |
| A | PHE116 |
Functional Information from PROSITE/UniProt
| site_id | PS00583 |
| Number of Residues | 25 |
| Details | PFKB_KINASES_1 pfkB family of carbohydrate kinases signature 1. GGvAgNMAfaIgVLGgevalvgaaG |
| Chain | Residue | Details |
| A | GLY47-GLY71 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"UniProtKB","id":"P9WID5","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | Binding site: {"description":"in other chain","evidences":[{"source":"Reference","evidenceCode":"ECO:0000305","citation":{"citationType":"submission","publicationDate":"AUG-2014","submissionDatabase":"PDB data bank","title":"Crystal structure of M.tuberculosis adenosine kinase complexed with 2-fluoro-adenosine.","authors":["Reddy M.C.M.","Palaninathan S.K.","Shetty N.D.","Owen J.L.","Watson M.D.","Sacchettini J.C."]}},{"source":"PDB","id":"4UBE","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"Reference","evidenceCode":"ECO:0000305","citation":{"citationType":"submission","publicationDate":"AUG-2014","submissionDatabase":"PDB data bank","title":"Crystal structure of M.tuberculosis adenosine kinase complexed with 2-fluoro-adenosine.","authors":["Reddy M.C.M.","Palaninathan S.K.","Shetty N.D.","Owen J.L.","Watson M.D.","Sacchettini J.C."]}},{"source":"PDB","id":"4UBE","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 7 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"P9WID5","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
