Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004497 | molecular_function | monooxygenase activity |
A | 0005506 | molecular_function | iron ion binding |
A | 0006707 | biological_process | cholesterol catabolic process |
A | 0008203 | biological_process | cholesterol metabolic process |
A | 0016042 | biological_process | lipid catabolic process |
A | 0016705 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
A | 0020037 | molecular_function | heme binding |
A | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 22 |
Details | binding site for residue HEM A 501 |
Chain | Residue |
A | GLU56 |
A | THR238 |
A | THR241 |
A | VAL280 |
A | ARG285 |
A | ALA335 |
A | PHE336 |
A | GLY337 |
A | PHE338 |
A | HIS341 |
A | CYS343 |
A | MET78 |
A | GLY345 |
A | HOH770 |
A | HOH777 |
A | ILE79 |
A | HIS86 |
A | ARG90 |
A | PHE97 |
A | GLY233 |
A | GLY234 |
A | THR237 |
Functional Information from PROSITE/UniProt
site_id | PS00086 |
Number of Residues | 10 |
Details | CYTOCHROME_P450 Cytochrome P450 cysteine heme-iron ligand signature. FGfGTHFCLG |
Chain | Residue | Details |
A | PHE336-GLY345 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | CYS343 | |