Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0008800 | molecular_function | beta-lactamase activity |
A | 0016787 | molecular_function | hydrolase activity |
A | 0017001 | biological_process | antibiotic catabolic process |
A | 0030655 | biological_process | beta-lactam antibiotic catabolic process |
A | 0046677 | biological_process | response to antibiotic |
B | 0008800 | molecular_function | beta-lactamase activity |
B | 0016787 | molecular_function | hydrolase activity |
B | 0017001 | biological_process | antibiotic catabolic process |
B | 0030655 | biological_process | beta-lactam antibiotic catabolic process |
B | 0046677 | biological_process | response to antibiotic |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 17 |
Details | binding site for residue 3GK A 301 |
Chain | Residue |
A | ASN104 |
A | SER237 |
A | GLY238 |
A | ASP240 |
A | 3GK302 |
A | HOH3535 |
A | HOH3605 |
A | HOH3718 |
A | HOH3765 |
A | TYR105 |
A | SER130 |
A | ASN132 |
A | PRO167 |
A | ASN170 |
A | THR171 |
A | THR235 |
A | GLY236 |
site_id | AC2 |
Number of Residues | 15 |
Details | binding site for residue 3GK A 302 |
Chain | Residue |
A | ASN104 |
A | TYR105 |
A | SER237 |
A | SER274 |
A | ARG276 |
A | 3GK301 |
A | HOH3535 |
A | HOH3580 |
A | HOH3593 |
A | HOH3651 |
A | HOH3658 |
A | HOH3668 |
A | HOH3691 |
A | HOH3697 |
A | HOH3881 |
site_id | AC3 |
Number of Residues | 8 |
Details | binding site for residue PO4 A 303 |
Chain | Residue |
A | ARG153 |
A | GLU158 |
A | HOH3506 |
A | HOH3523 |
B | HIS197 |
B | ARG204 |
B | HOH515 |
B | HOH783 |
site_id | AC4 |
Number of Residues | 18 |
Details | binding site for residue 3GK B 301 |
Chain | Residue |
B | ASN104 |
B | TYR105 |
B | SER130 |
B | ASN132 |
B | PRO167 |
B | ASN170 |
B | THR171 |
B | THR235 |
B | GLY236 |
B | SER237 |
B | GLY238 |
B | ASP240 |
B | ARG256 |
B | 3GK302 |
B | HOH424 |
B | HOH518 |
B | HOH573 |
B | HOH612 |
site_id | AC5 |
Number of Residues | 13 |
Details | binding site for residue 3GK B 302 |
Chain | Residue |
B | ASN104 |
B | TYR105 |
B | SER237 |
B | ARG256 |
B | SER274 |
B | ARG276 |
B | 3GK301 |
B | HOH416 |
B | HOH424 |
B | HOH451 |
B | HOH488 |
B | HOH599 |
B | HOH693 |
site_id | AC6 |
Number of Residues | 9 |
Details | binding site for residue PO4 B 303 |
Chain | Residue |
A | PRO177 |
A | HOH3707 |
B | THR202 |
B | GLN203 |
B | HOH418 |
B | HOH426 |
B | HOH439 |
B | HOH651 |
B | HOH707 |
site_id | AC7 |
Number of Residues | 8 |
Details | binding site for residue PO4 B 304 |
Chain | Residue |
A | TYR241 |
A | HOH3566 |
A | HOH3638 |
A | HOH3695 |
B | ARG65 |
B | HOH443 |
B | HOH597 |
B | HOH631 |
Functional Information from PROSITE/UniProt
site_id | PS00146 |
Number of Residues | 16 |
Details | BETA_LACTAMASE_A Beta-lactamase class-A active site. FpMCSTsKvmaAAAVL |
Chain | Residue | Details |
A | PHE66-LEU81 | |