Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

4U8O

Structure of Aspergillus fumigatus UDP-Galactopyranose mutase mutant N207A complexed with UDP

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0008767	molecular_function	UDP-galactopyranose mutase activity
A	0016853	molecular_function	isomerase activity
A	0071555	biological_process	cell wall organization
B	0000166	molecular_function	nucleotide binding
B	0008767	molecular_function	UDP-galactopyranose mutase activity
B	0016853	molecular_function	isomerase activity
B	0071555	biological_process	cell wall organization
C	0000166	molecular_function	nucleotide binding
C	0008767	molecular_function	UDP-galactopyranose mutase activity
C	0016853	molecular_function	isomerase activity
C	0071555	biological_process	cell wall organization
D	0000166	molecular_function	nucleotide binding
D	0008767	molecular_function	UDP-galactopyranose mutase activity
D	0016853	molecular_function	isomerase activity
D	0071555	biological_process	cell wall organization

Functional Information from PDB Data

site_id	AC1
Number of Residues	31
Details	binding site for residue FDA A 601

Chain	Residue
A	GLY14
A	VAL60
A	GLY62
A	HIS63
A	VAL64
A	GLY240
A	VAL242
A	MET269
A	GLU373
A	GLY418
A	GLY446
A	GLY16
A	ARG447
A	GLY456
A	ASN457
A	GLN458
A	SER461
A	HOH711
A	HOH723
A	HOH747
A	HOH756
A	HOH780
A	PRO17
A	HOH806
A	HOH828
A	THR18
A	ASP38
A	SER39
A	GLY45
A	LEU46
A	ALA47

site_id	AC2
Number of Residues	17
Details	binding site for residue UDP A 602

Chain	Residue
A	VAL95
A	TYR104
A	PHE106
A	GLN107
A	PHE158
A	MET159
A	TYR162
A	ASN163
A	TRP167
A	ARG182
A	VAL183
A	TYR317
A	ARG327
A	TYR419
A	TYR453
A	HOH740
A	HOH800

site_id	AC3
Number of Residues	4
Details	binding site for residue SO4 A 603

Chain	Residue
A	PRO307
A	GLU308
A	ARG309
A	HOH839

site_id	AC4
Number of Residues	2
Details	binding site for residue SO4 A 604

Chain	Residue
A	TYR87
A	THR88

site_id	AC5
Number of Residues	4
Details	binding site for residue SO4 A 605

Chain	Residue
A	VAL147
A	THR152
A	ARG160
A	HOH825

site_id	AC6
Number of Residues	2
Details	binding site for residue SO4 A 606

Chain	Residue
A	LYS70
A	ARG496

site_id	AC7
Number of Residues	2
Details	binding site for residue SO4 A 607

Chain	Residue
A	ARG306
A	ASP312

site_id	AC8
Number of Residues	3
Details	binding site for residue SO4 A 608

Chain	Residue
A	ASN40
A	ASP50
A	ARG413

site_id	AC9
Number of Residues	7
Details	binding site for residue UDP A 609

Chain	Residue
A	LYS288
A	LEU290
A	PHE291
A	TYR292
A	SER377
A	SER378
A	HOH781

site_id	AD1
Number of Residues	4
Details	binding site for residue EDO A 610

Chain	Residue
A	TRP443
A	ASN471
C	GLU494
C	HOH730

site_id	AD2
Number of Residues	3
Details	binding site for residue EDO A 611

Chain	Residue
A	ARG303
A	ASP405
A	GLU406

site_id	AD3
Number of Residues	29
Details	binding site for residue FDA B 601

Chain	Residue
B	GLY456
B	ASN457
B	GLN458
B	SER461
B	EDO612
B	HOH729
B	HOH738
B	HOH837
B	HOH865
B	GLY14
B	GLY16
B	PRO17
B	THR18
B	ASP38
B	SER39
B	GLY45
B	LEU46
B	ALA47
B	VAL60
B	GLY62
B	HIS63
B	VAL64
B	GLY240
B	VAL242
B	MET269
B	GLU373
B	GLY418
B	GLY446
B	ARG447

site_id	AD4
Number of Residues	15
Details	binding site for residue UDP B 602

Chain	Residue
B	VAL95
B	TYR104
B	PRO105
B	PHE106
B	GLN107
B	PHE158
B	ASN163
B	TRP167
B	ARG182
B	VAL183
B	TYR317
B	ARG327
B	TYR419
B	TYR453
B	EDO612

site_id	AD5
Number of Residues	5
Details	binding site for residue SO4 B 603

Chain	Residue
B	PRO307
B	GLU308
B	ARG309
B	LYS402
B	HOH871

site_id	AD6
Number of Residues	3
Details	binding site for residue SO4 B 604

Chain	Residue
B	TYR87
B	THR88
B	HOH857

site_id	AD7
Number of Residues	2
Details	binding site for residue SO4 B 605

Chain	Residue
B	ARG306
B	ASP312

site_id	AD8
Number of Residues	2
Details	binding site for residue SO4 B 606

Chain	Residue
B	LYS70
B	ARG496

site_id	AD9
Number of Residues	3
Details	binding site for residue SO4 B 607

Chain	Residue
B	ASN40
B	ASP50
B	ARG413

site_id	AE1
Number of Residues	2
Details	binding site for residue SO4 B 608

Chain	Residue
B	LYS82
B	GLU83

site_id	AE2
Number of Residues	6
Details	binding site for residue UDP B 609

Chain	Residue
B	LYS288
B	LEU290
B	PHE291
B	TYR292
B	SER377
B	SER378

site_id	AE3
Number of Residues	5
Details	binding site for residue EDO B 610

Chain	Residue
B	ASN322
B	CYS323
B	PRO324
B	ASP390
B	HOH702

site_id	AE4
Number of Residues	5
Details	binding site for residue EDO B 611

Chain	Residue
B	TRP443
B	ASN471
B	HOH830
D	GLU494
D	HOH709

site_id	AE5
Number of Residues	6
Details	binding site for residue EDO B 612

Chain	Residue
B	GLY62
B	TRP315
B	ARG327
B	FDA601
B	UDP602
B	HOH740

site_id	AE6
Number of Residues	30
Details	binding site for residue FDA C 601

Chain	Residue
C	GLY14
C	GLY16
C	PRO17
C	THR18
C	ASP38
C	SER39
C	GLY45
C	LEU46
C	ALA47
C	VAL60
C	GLY62
C	HIS63
C	VAL64
C	GLY240
C	VAL242
C	MET269
C	GLU373
C	GLY418
C	TYR419
C	GLY446
C	ARG447
C	GLY456
C	ASN457
C	GLN458
C	SER461
C	EDO611
C	HOH715
C	HOH794
C	HOH828
C	HOH845

site_id	AE7
Number of Residues	4
Details	binding site for residue SO4 C 602

Chain	Residue
C	PRO307
C	GLU308
C	ARG309
C	HOH793

site_id	AE8
Number of Residues	3
Details	binding site for residue SO4 C 603

Chain	Residue
C	VAL147
C	THR152
C	ARG160

site_id	AE9
Number of Residues	3
Details	binding site for residue SO4 C 604

Chain	Residue
C	PRO114
C	LYS115
C	HOH811

site_id	AF1
Number of Residues	2
Details	binding site for residue SO4 C 605

Chain	Residue
C	ARG306
C	ASP312

site_id	AF2
Number of Residues	4
Details	binding site for residue SO4 C 606

Chain	Residue
C	ARG91
C	TYR104
C	ASN203
C	HOH767

site_id	AF3
Number of Residues	3
Details	binding site for residue SO4 C 607

Chain	Residue
B	ASN248
C	LYS70
C	ARG496

site_id	AF4
Number of Residues	2
Details	binding site for residue SO4 C 608

Chain	Residue
C	TYR87
C	THR88

site_id	AF5
Number of Residues	6
Details	binding site for residue UDP C 609

Chain	Residue
C	LYS288
C	LEU290
C	PHE291
C	TYR292
C	SER377
C	SER378

site_id	AF6
Number of Residues	3
Details	binding site for residue EDO C 610

Chain	Residue
A	GLU494
A	HOH729
C	ASN471

site_id	AF7
Number of Residues	4
Details	binding site for residue EDO C 611

Chain	Residue
C	VAL64
C	PHE66
C	ARG91
C	FDA601

site_id	AF8
Number of Residues	3
Details	binding site for residue EDO C 612

Chain	Residue
C	ARG303
C	ASP405
C	GLU406

site_id	AF9
Number of Residues	30
Details	binding site for residue FDA D 601

Chain	Residue
D	GLY14
D	GLY16
D	PRO17
D	THR18
D	ASP38
D	SER39
D	GLY45
D	LEU46
D	ALA47
D	VAL60
D	GLY62
D	HIS63
D	VAL64
D	GLY240
D	VAL242
D	MET269
D	GLU373
D	GLY418
D	GLY446
D	ARG447
D	GLY456
D	ASN457
D	GLN458
D	SER461
D	EDO611
D	HOH729
D	HOH739
D	HOH791
D	HOH828
D	HOH857

site_id	AG1
Number of Residues	6
Details	binding site for residue SO4 D 602

Chain	Residue
D	PRO307
D	GLU308
D	ARG309
D	LYS402
D	HOH806
D	HOH870

site_id	AG2
Number of Residues	3
Details	binding site for residue SO4 D 603

Chain	Residue
D	PRO114
D	LYS115
D	HOH860

site_id	AG3
Number of Residues	4
Details	binding site for residue SO4 D 604

Chain	Residue
D	ARG91
D	TYR104
D	ASN203
D	HOH859

site_id	AG4
Number of Residues	2
Details	binding site for residue SO4 D 605

Chain	Residue
D	ARG306
D	ASP312

site_id	AG5
Number of Residues	3
Details	binding site for residue SO4 D 606

Chain	Residue
D	ASN40
D	ASP50
D	ARG413

site_id	AG6
Number of Residues	3
Details	binding site for residue SO4 D 607

Chain	Residue
D	TRP86
D	TYR87
D	THR88

site_id	AG7
Number of Residues	3
Details	binding site for residue SO4 D 608

Chain	Residue
D	THR152
D	ARG160
D	HOH827

site_id	AG8
Number of Residues	6
Details	binding site for residue UDP D 609

Chain	Residue
D	LYS288
D	LEU290
D	PHE291
D	TYR292
D	SER377
D	SER378

site_id	AG9
Number of Residues	4
Details	binding site for residue EDO D 610

Chain	Residue
B	GLU494
B	HOH762
D	TRP443
D	ASN471

site_id	AH1
Number of Residues	4
Details	binding site for residue EDO D 611

Chain	Residue
D	GLY62
D	TRP315
D	FDA601
D	HOH718

site_id	AH2
Number of Residues	5
Details	binding site for residue EDO D 612

Chain	Residue
D	MET125
D	MET149
D	ALA185
D	ASN187
D	HOH807

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	32
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22294687","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22334662","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3UKA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UKH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UKK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UKL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UKP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UTE","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22334662","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3UKP","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22334662","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3UKF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UKP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UKQ","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	28
Details	Binding site: {"evidences":[{"source":"PubMed","id":"23036087","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5VWT","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI5
Number of Residues	32
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22294687","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22334662","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3UKF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UKH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UKP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UKQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UTH","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI6
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22334662","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3UKH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UKP","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI7
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22294687","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22334662","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3UKH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UKQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UTH","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI8
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22294687","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22334662","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3UKF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UKH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UTH","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI9
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22334662","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3UKH","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)