Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

4U8N

Structure of Aspergillus fumigatus UDP-Galactopyranose mutase mutant F66A complexed with UDP

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0008767	molecular_function	UDP-galactopyranose mutase activity
A	0016853	molecular_function	isomerase activity
A	0071555	biological_process	cell wall organization
B	0000166	molecular_function	nucleotide binding
B	0008767	molecular_function	UDP-galactopyranose mutase activity
B	0016853	molecular_function	isomerase activity
B	0071555	biological_process	cell wall organization
C	0000166	molecular_function	nucleotide binding
C	0008767	molecular_function	UDP-galactopyranose mutase activity
C	0016853	molecular_function	isomerase activity
C	0071555	biological_process	cell wall organization
D	0000166	molecular_function	nucleotide binding
D	0008767	molecular_function	UDP-galactopyranose mutase activity
D	0016853	molecular_function	isomerase activity
D	0071555	biological_process	cell wall organization

Functional Information from PDB Data

site_id	AC1
Number of Residues	31
Details	binding site for residue FDA A 601

Chain	Residue
A	GLY14
A	ALA47
A	VAL60
A	GLY62
A	HIS63
A	VAL64
A	GLY240
A	VAL242
A	GLU373
A	GLY418
A	GLY446
A	GLY16
A	ARG447
A	GLY456
A	ASN457
A	GLN458
A	SER461
A	EDO608
A	HOH732
A	HOH737
A	HOH738
A	HOH775
A	PRO17
A	HOH781
A	HOH787
A	THR18
A	ASP38
A	SER39
A	GLY44
A	GLY45
A	LEU46

site_id	AC2
Number of Residues	20
Details	binding site for residue UDP A 602

Chain	Residue
A	VAL95
A	TYR104
A	PRO105
A	PHE106
A	GLN107
A	PHE158
A	MET159
A	ASN163
A	TRP167
A	ARG182
A	VAL183
A	TYR317
A	ARG327
A	TYR419
A	TYR453
A	EDO608
A	HOH726
A	HOH739
A	HOH741
A	HOH777

site_id	AC3
Number of Residues	6
Details	binding site for residue UDP A 603

Chain	Residue
A	LYS288
A	LEU290
A	PHE291
A	TYR292
A	SER377
A	SER378

site_id	AC4
Number of Residues	4
Details	binding site for residue SO4 A 604

Chain	Residue
A	PRO307
A	GLU308
A	ARG309
A	LYS402

site_id	AC5
Number of Residues	2
Details	binding site for residue SO4 A 605

Chain	Residue
A	LYS70
A	ARG496

site_id	AC6
Number of Residues	4
Details	binding site for residue SO4 A 606

Chain	Residue
A	ASN187
A	LYS189
A	HOH782
A	HOH804

site_id	AC7
Number of Residues	4
Details	binding site for residue EDO A 607

Chain	Residue
A	TRP443
A	ASN471
C	GLU494
C	HOH757

site_id	AC8
Number of Residues	6
Details	binding site for residue EDO A 608

Chain	Residue
A	VAL64
A	TRP315
A	ARG327
A	FDA601
A	UDP602
A	HOH723

site_id	AC9
Number of Residues	5
Details	binding site for residue EDO A 609

Chain	Residue
A	CYS97
A	GLN98
A	GLU117
A	LEU157
A	GLU320

site_id	AD1
Number of Residues	29
Details	binding site for residue FDA B 601

Chain	Residue
B	GLY418
B	GLY446
B	ARG447
B	GLY456
B	ASN457
B	GLN458
B	SER461
B	EDO611
B	HOH738
B	HOH756
B	HOH782
B	HOH795
B	GLY14
B	GLY16
B	PRO17
B	THR18
B	ASP38
B	SER39
B	GLY45
B	LEU46
B	ALA47
B	VAL60
B	GLY62
B	HIS63
B	VAL64
B	GLY240
B	VAL242
B	MET269
B	GLU373

site_id	AD2
Number of Residues	20
Details	binding site for residue UDP B 602

Chain	Residue
B	VAL95
B	TYR104
B	PRO105
B	PHE106
B	GLN107
B	PHE158
B	ASN163
B	TRP167
B	ARG182
B	VAL183
B	TYR317
B	ARG327
B	TYR419
B	TYR453
B	EDO611
B	HOH732
B	HOH743
B	HOH745
B	HOH752
B	HOH804

site_id	AD3
Number of Residues	6
Details	binding site for residue UDP B 603

Chain	Residue
B	LYS288
B	LEU290
B	PHE291
B	TYR292
B	SER377
B	SER378

site_id	AD4
Number of Residues	5
Details	binding site for residue SO4 B 604

Chain	Residue
B	PRO307
B	GLU308
B	ARG309
B	LYS402
B	HOH823

site_id	AD5
Number of Residues	3
Details	binding site for residue SO4 B 605

Chain	Residue
B	ASN40
B	ASP50
B	ARG413

site_id	AD6
Number of Residues	1
Details	binding site for residue SO4 B 606

Chain	Residue
B	ARG496

site_id	AD7
Number of Residues	2
Details	binding site for residue SO4 B 607

Chain	Residue
B	ASN187
B	LYS189

site_id	AD8
Number of Residues	2
Details	binding site for residue EDO B 608

Chain	Residue
B	ASP321
B	EDO609

site_id	AD9
Number of Residues	5
Details	binding site for residue EDO B 609

Chain	Residue
B	ASN322
B	CYS323
B	PRO324
B	ASP390
B	EDO608

site_id	AE1
Number of Residues	3
Details	binding site for residue EDO B 610

Chain	Residue
B	TRP443
B	ASN471
D	GLU494

site_id	AE2
Number of Residues	7
Details	binding site for residue EDO B 611

Chain	Residue
B	GLY62
B	VAL64
B	TRP315
B	ARG327
B	FDA601
B	UDP602
B	HOH716

site_id	AE3
Number of Residues	28
Details	binding site for residue FDA C 601

Chain	Residue
C	GLY14
C	GLY16
C	PRO17
C	THR18
C	ASP38
C	SER39
C	GLY45
C	LEU46
C	ALA47
C	VAL60
C	GLY62
C	HIS63
C	VAL64
C	GLY240
C	VAL242
C	MET269
C	GLU373
C	GLY418
C	TYR419
C	GLY446
C	ARG447
C	GLY456
C	ASN457
C	GLN458
C	SER461
C	EDO607
C	HOH732
C	HOH744

site_id	AE4
Number of Residues	5
Details	binding site for residue SO4 C 602

Chain	Residue
C	PRO307
C	GLU308
C	ARG309
C	LYS402
C	HOH763

site_id	AE5
Number of Residues	3
Details	binding site for residue SO4 C 603

Chain	Residue
C	VAL147
C	THR152
C	ARG160

site_id	AE6
Number of Residues	2
Details	binding site for residue SO4 C 604

Chain	Residue
B	ASN248
C	ARG496

site_id	AE7
Number of Residues	2
Details	binding site for residue SO4 C 605

Chain	Residue
C	ASN40
C	ARG413

site_id	AE8
Number of Residues	4
Details	binding site for residue EDO C 606

Chain	Residue
A	GLU494
C	TRP443
C	ASN471
C	HOH765

site_id	AE9
Number of Residues	5
Details	binding site for residue EDO C 607

Chain	Residue
C	GLY62
C	TRP315
C	ARG327
C	FDA601
C	HOH710

site_id	AF1
Number of Residues	3
Details	binding site for residue EDO C 608

Chain	Residue
C	ARG303
C	ASP405
C	GLU406

site_id	AF2
Number of Residues	28
Details	binding site for residue FDA D 601

Chain	Residue
D	GLY14
D	GLY16
D	PRO17
D	THR18
D	ASP38
D	SER39
D	GLY45
D	LEU46
D	ALA47
D	VAL60
D	GLY62
D	HIS63
D	VAL64
D	GLY240
D	VAL242
D	MET269
D	GLU373
D	GLY418
D	GLY446
D	ARG447
D	GLY456
D	ASN457
D	GLN458
D	SER461
D	HOH716
D	HOH744
D	HOH767
D	HOH781

site_id	AF3
Number of Residues	4
Details	binding site for residue SO4 D 602

Chain	Residue
D	PRO307
D	GLU308
D	ARG309
D	LYS402

site_id	AF4
Number of Residues	2
Details	binding site for residue SO4 D 603

Chain	Residue
D	PRO114
D	LYS115

site_id	AF5
Number of Residues	4
Details	binding site for residue EDO D 604

Chain	Residue
B	GLU494
D	TRP443
D	ASN471
D	HOH748

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	32
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22294687","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22334662","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3UKA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UKH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UKK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UKL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UKP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UTE","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22334662","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3UKP","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22334662","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3UKF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UKP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UKQ","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	28
Details	Binding site: {"evidences":[{"source":"PubMed","id":"23036087","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5VWT","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI5
Number of Residues	32
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22294687","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22334662","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3UKF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UKH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UKP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UKQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UTH","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI6
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22334662","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3UKH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UKP","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI7
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22294687","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22334662","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3UKH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UKQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UTH","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI8
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22294687","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22334662","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3UKF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UKH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UTH","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI9
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22334662","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3UKH","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)