Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 33 |
| Details | binding site for residue FDA A 601 |
| Chain | Residue |
| A | GLY14 |
| A | VAL60 |
| A | GLY62 |
| A | HIS63 |
| A | VAL64 |
| A | GLY240 |
| A | LYS241 |
| A | VAL242 |
| A | MET269 |
| A | THR295 |
| A | GLU373 |
| A | GLY16 |
| A | GLY418 |
| A | GLY446 |
| A | ARG447 |
| A | GLY456 |
| A | ASN457 |
| A | GLN458 |
| A | SER461 |
| A | EDO612 |
| A | HOH734 |
| A | HOH741 |
| A | PRO17 |
| A | HOH773 |
| A | HOH844 |
| A | HOH850 |
| A | HOH854 |
| A | THR18 |
| A | ASP38 |
| A | SER39 |
| A | GLY45 |
| A | LEU46 |
| A | ALA47 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 602 |
| Chain | Residue |
| A | PRO307 |
| A | GLU308 |
| A | ARG309 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 603 |
| Chain | Residue |
| A | ASN40 |
| A | ARG413 |
| A | HOH779 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 A 604 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 A 605 |
| Chain | Residue |
| A | LYS70 |
| A | ARG496 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 606 |
| Chain | Residue |
| A | VAL147 |
| A | THR152 |
| A | ARG160 |
| A | HOH704 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 A 607 |
| Chain | Residue |
| A | ARG91 |
| A | TYR104 |
| A | ASN203 |
| A | HOH742 |
| A | HOH868 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 608 |
| Chain | Residue |
| A | GLU494 |
| A | HOH832 |
| C | TRP443 |
| C | ASN471 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 609 |
| Chain | Residue |
| A | TRP443 |
| A | ASN471 |
| C | GLU494 |
| site_id | AD1 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 610 |
| Chain | Residue |
| A | TYR104 |
| A | MET159 |
| A | ASN163 |
| A | HOH878 |
| site_id | AD2 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 611 |
| Chain | Residue |
| A | ARG303 |
| A | ASP405 |
| A | GLU406 |
| site_id | AD3 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 612 |
| Chain | Residue |
| A | GLY62 |
| A | VAL64 |
| A | TRP315 |
| A | ARG327 |
| A | FDA601 |
| site_id | AD4 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 613 |
| Chain | Residue |
| A | PHE66 |
| A | SER67 |
| A | THR209 |
| A | HOH750 |
| site_id | AD5 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 614 |
| Chain | Residue |
| A | TYR453 |
| A | ASN457 |
| A | HOH857 |
| site_id | AD6 |
| Number of Residues | 31 |
| Details | binding site for residue FDA B 601 |
| Chain | Residue |
| B | ARG447 |
| B | GLY456 |
| B | ASN457 |
| B | GLN458 |
| B | SER461 |
| B | EDO611 |
| B | HOH764 |
| B | HOH774 |
| B | HOH789 |
| B | HOH816 |
| B | GLY14 |
| B | GLY16 |
| B | PRO17 |
| B | THR18 |
| B | ASP38 |
| B | SER39 |
| B | GLY45 |
| B | LEU46 |
| B | ALA47 |
| B | VAL60 |
| B | GLY62 |
| B | HIS63 |
| B | VAL64 |
| B | GLY240 |
| B | LYS241 |
| B | VAL242 |
| B | MET269 |
| B | THR295 |
| B | GLU373 |
| B | GLY418 |
| B | GLY446 |
| site_id | AD7 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 B 602 |
| Chain | Residue |
| B | GLU308 |
| B | ARG309 |
| B | LYS402 |
| B | HOH856 |
| site_id | AD8 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 B 603 |
| Chain | Residue |
| B | ASN40 |
| B | ASP50 |
| B | ARG413 |
| site_id | AD9 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 B 604 |
| Chain | Residue |
| B | PRO114 |
| B | LYS115 |
| B | ASN383 |
| B | THR386 |
| B | HOH703 |
| site_id | AE1 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 B 605 |
| Chain | Residue |
| B | ARG91 |
| B | TYR104 |
| B | ASN203 |
| B | TRP315 |
| B | HOH772 |
| B | HOH900 |
| site_id | AE2 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 B 606 |
| Chain | Residue |
| B | LYS70 |
| B | ARG496 |
| site_id | AE3 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 B 607 |
| Chain | Residue |
| B | VAL147 |
| B | THR152 |
| B | ARG160 |
| B | HOH931 |
| B | HOH938 |
| site_id | AE4 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 608 |
| Chain | Residue |
| B | PRO114 |
| B | GLU116 |
| B | ASP390 |
| B | EDO609 |
| B | EDO613 |
| B | HOH711 |
| site_id | AE5 |
| Number of Residues | 7 |
| Details | binding site for residue EDO B 609 |
| Chain | Residue |
| B | ASN322 |
| B | CYS323 |
| B | PRO324 |
| B | ASP390 |
| B | ASN397 |
| B | EDO608 |
| B | HOH706 |
| site_id | AE6 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 610 |
| Chain | Residue |
| B | TRP443 |
| B | ASN471 |
| D | GLU494 |
| site_id | AE7 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 611 |
| Chain | Residue |
| B | GLY62 |
| B | VAL64 |
| B | TRP315 |
| B | ARG327 |
| B | FDA601 |
| B | HOH740 |
| site_id | AE8 |
| Number of Residues | 2 |
| Details | binding site for residue EDO B 612 |
| Chain | Residue |
| B | TYR453 |
| B | ASN457 |
| site_id | AE9 |
| Number of Residues | 7 |
| Details | binding site for residue EDO B 613 |
| Chain | Residue |
| B | GLN98 |
| B | GLU116 |
| B | GLU117 |
| B | ASP321 |
| B | CYS323 |
| B | PRO324 |
| B | EDO608 |
| site_id | AF1 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 614 |
| Chain | Residue |
| B | GLU117 |
| B | LYS120 |
| B | HOH710 |
| site_id | AF2 |
| Number of Residues | 28 |
| Details | binding site for residue FDA C 601 |
| Chain | Residue |
| C | GLY14 |
| C | GLY16 |
| C | PRO17 |
| C | THR18 |
| C | ASP38 |
| C | SER39 |
| C | GLY45 |
| C | LEU46 |
| C | ALA47 |
| C | VAL60 |
| C | GLY62 |
| C | HIS63 |
| C | VAL64 |
| C | GLY240 |
| C | VAL242 |
| C | MET269 |
| C | GLU373 |
| C | TYR419 |
| C | GLY446 |
| C | ARG447 |
| C | GLY456 |
| C | ASN457 |
| C | GLN458 |
| C | SER461 |
| C | EDO608 |
| C | HOH723 |
| C | HOH738 |
| C | HOH824 |
| site_id | AF3 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 C 602 |
| Chain | Residue |
| C | PRO307 |
| C | GLU308 |
| C | ARG309 |
| C | LYS402 |
| C | HOH733 |
| site_id | AF4 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 C 603 |
| Chain | Residue |
| C | THR152 |
| C | ARG160 |
| site_id | AF5 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 C 604 |
| Chain | Residue |
| C | PRO114 |
| C | LYS115 |
| C | HOH792 |
| site_id | AF6 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 C 605 |
| Chain | Residue |
| C | LYS70 |
| C | ARG496 |
| site_id | AF7 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 C 606 |
| Chain | Residue |
| C | ARG91 |
| C | TYR104 |
| C | ASN203 |
| C | HOH814 |
| site_id | AF8 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 C 607 |
| Chain | Residue |
| C | ASN40 |
| C | ASP50 |
| C | ARG413 |
| site_id | AF9 |
| Number of Residues | 5 |
| Details | binding site for residue EDO C 608 |
| Chain | Residue |
| C | VAL64 |
| C | PHE66 |
| C | ARG91 |
| C | ASN457 |
| C | FDA601 |
| site_id | AG1 |
| Number of Residues | 28 |
| Details | binding site for residue FDA D 601 |
| Chain | Residue |
| D | GLY14 |
| D | GLY16 |
| D | PRO17 |
| D | THR18 |
| D | ASP38 |
| D | SER39 |
| D | GLY45 |
| D | LEU46 |
| D | ALA47 |
| D | VAL60 |
| D | GLY62 |
| D | HIS63 |
| D | VAL64 |
| D | GLY240 |
| D | VAL242 |
| D | MET269 |
| D | THR295 |
| D | GLU373 |
| D | GLY418 |
| D | TYR419 |
| D | GLY446 |
| D | ARG447 |
| D | GLY456 |
| D | ASN457 |
| D | GLN458 |
| D | SER461 |
| D | HOH752 |
| D | HOH753 |
| site_id | AG2 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 D 602 |
| Chain | Residue |
| D | PRO307 |
| D | GLU308 |
| D | ARG309 |
| D | LYS402 |
| site_id | AG3 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 D 603 |
| Chain | Residue |
| D | THR152 |
| D | ARG160 |
| site_id | AG4 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 D 604 |
| Chain | Residue |
| A | VAL382 |
| A | ASN383 |
| A | GLN384 |
| A | GLU385 |
| D | LYS199 |
| D | THR200 |
| D | HOH703 |
| site_id | AG5 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 D 605 |
| Chain | Residue |
| D | ASN40 |
| D | ASP50 |
| D | ARG413 |
| site_id | AG6 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 D 606 |
| Chain | Residue |
| D | PRO114 |
| D | LYS115 |
| site_id | AG7 |
| Number of Residues | 3 |
| Details | binding site for residue EDO D 607 |
| Chain | Residue |
| B | GLU494 |
| D | TRP443 |
| D | ASN471 |
| site_id | AG8 |
| Number of Residues | 4 |
| Details | binding site for residue EDO D 608 |
| Chain | Residue |
| D | GLN107 |
| D | MET149 |
| D | PRO186 |
| D | ASN187 |
