4U7B

Crystal structure of a pre-cleavage Mos1 transpososome

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000014	molecular_function	single-stranded DNA endodeoxyribonuclease activity
A	0000729	biological_process	DNA double-strand break processing
A	0000793	cellular_component	condensed chromosome
A	0003676	molecular_function	nucleic acid binding
A	0003677	molecular_function	DNA binding
A	0003690	molecular_function	double-stranded DNA binding
A	0003697	molecular_function	single-stranded DNA binding
A	0004518	molecular_function	nuclease activity
A	0004519	molecular_function	endonuclease activity
A	0005634	cellular_component	nucleus
A	0006303	biological_process	double-strand break repair via nonhomologous end joining
A	0006310	biological_process	DNA recombination
A	0006338	biological_process	chromatin remodeling
A	0015074	biological_process	DNA integration
A	0016787	molecular_function	hydrolase activity
A	0031297	biological_process	replication fork processing
A	0035861	cellular_component	site of double-strand break
A	0042800	molecular_function	histone H3K4 methyltransferase activity
A	0044547	molecular_function	DNA topoisomerase binding
A	0044774	biological_process	mitotic DNA integrity checkpoint signaling
A	0046872	molecular_function	metal ion binding
A	0046975	molecular_function	histone H3K36 methyltransferase activity
B	0000014	molecular_function	single-stranded DNA endodeoxyribonuclease activity
B	0000729	biological_process	DNA double-strand break processing
B	0000793	cellular_component	condensed chromosome
B	0003676	molecular_function	nucleic acid binding
B	0003677	molecular_function	DNA binding
B	0003690	molecular_function	double-stranded DNA binding
B	0003697	molecular_function	single-stranded DNA binding
B	0004518	molecular_function	nuclease activity
B	0004519	molecular_function	endonuclease activity
B	0005634	cellular_component	nucleus
B	0006303	biological_process	double-strand break repair via nonhomologous end joining
B	0006310	biological_process	DNA recombination
B	0006338	biological_process	chromatin remodeling
B	0015074	biological_process	DNA integration
B	0016787	molecular_function	hydrolase activity
B	0031297	biological_process	replication fork processing
B	0035861	cellular_component	site of double-strand break
B	0042800	molecular_function	histone H3K4 methyltransferase activity
B	0044547	molecular_function	DNA topoisomerase binding
B	0044774	biological_process	mitotic DNA integrity checkpoint signaling
B	0046872	molecular_function	metal ion binding
B	0046975	molecular_function	histone H3K36 methyltransferase activity
G	0000014	molecular_function	single-stranded DNA endodeoxyribonuclease activity
G	0000729	biological_process	DNA double-strand break processing
G	0000793	cellular_component	condensed chromosome
G	0003676	molecular_function	nucleic acid binding
G	0003677	molecular_function	DNA binding
G	0003690	molecular_function	double-stranded DNA binding
G	0003697	molecular_function	single-stranded DNA binding
G	0004518	molecular_function	nuclease activity
G	0004519	molecular_function	endonuclease activity
G	0005634	cellular_component	nucleus
G	0006303	biological_process	double-strand break repair via nonhomologous end joining
G	0006310	biological_process	DNA recombination
G	0006338	biological_process	chromatin remodeling
G	0015074	biological_process	DNA integration
G	0016787	molecular_function	hydrolase activity
G	0031297	biological_process	replication fork processing
G	0035861	cellular_component	site of double-strand break
G	0042800	molecular_function	histone H3K4 methyltransferase activity
G	0044547	molecular_function	DNA topoisomerase binding
G	0044774	biological_process	mitotic DNA integrity checkpoint signaling
G	0046872	molecular_function	metal ion binding
G	0046975	molecular_function	histone H3K36 methyltransferase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	binding site for residue SO4 C 101

Chain	Residue
C	DG13
C	DT14
D	DT45

---

site_id	AC2
Number of Residues	5
Details	binding site for residue SO4 D 101

Chain	Residue
C	DA11
C	DA12
D	DT46
D	DG47
D	DT48

---

site_id	AC3
Number of Residues	2
Details	binding site for residue SO4 E 101

Chain	Residue
E	DT14
E	DG13

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	156
Details	DNA binding: {"description":"H-T-H motif"}

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Residue

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site_id	SWS_FT_FI2
Number of Residues	36
Details	Region: {"description":"Linker"}

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Residue

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site_id	SWS_FT_FI3
Number of Residues	657
Details	Region: {"description":"Catalytic"}

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Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	9
Details	Binding site: {}

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Residue

Details

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site_id	SWS_FT_FI5
Number of Residues	12
Details	Site: {"description":"Important for base-specific DNA-binding"}

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Residue

Details

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site_id	SWS_FT_FI6
Number of Residues	3
Details	Site: {"description":"Important for target DNA recognition and for strand transfer activity"}

Chain

Residue

Details

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